Сотрудник:
Лузина Ольга Анатольевна
Занимаемые должности:
внс(дхн) ЛФАВ
Публикации (по IF ) сотрудника подразделения БД НИОХ СО РАН
- M.V. Khvostov, E.D. Gladkova, S.A. Borisov, M.S. Fedotova, N.A. Zhukova, M.K. Marenina, Yu.V. Meshkova, N. Valutsa, O.A. Luzina, T.G. Tolstikova, N.F. Salakhutdinov
9-N-n-alkyl Berberine Derivatives: Hypoglycemic Activity Evaluation
Pharmaceutics 2023, 15(1), 44; doi:10.3390/pharmaceutics15010044, IF=6.525
- M.V. Khvostov, E.D. Gladkova, S.A. Borisov, N.A. Zhukova, M.K. Marenina, Yu.V. Meshkova, O.A. Luzina, T.G. Tolstikova, N.F. Salakhutdinov
Discovery of the First in Class 9-N-Berberine Derivative as Hypoglycemic Agent with Extra-Strong Action
Pharmaceutics 2021, 13(12), 2138 doi:10.3390/pharmaceutics13122138, IF=6.321
- M.V. Khvostov, E.D. Gladkova, S.A. Borisov, M.S. Fedotova, N.A. Zhukova, M.K. Marenina, Yu.V. Meshkova, O.A. Luzina, T.G. Tolstikova, N.F. Salakhutdinov
Study of Hypoglycemic Activity of Novel 9-N-alkyltetrahydroberberine Derivatives
Int. J. Mol. Sci. 2022, 23(22), 14186 doi:10.3390/ijms232214186, IF=6.208
- N.S. Dyrkheeva, A.S. Filimonov, O.A. Luzina, K.A. Orlova, I.A. Chernyshova, T.E. Kornienko, A.A. Malakhova, S.P. Medvedev, A.L. Zakharenko, E.S. Ilina, R.O. Anarbaev, K.N. Naumenko, K.V. Klabenkova, E.A. Burakova, D.A. Stetsenko, S.M. Zakian, N.F. Salakhutdinov, O.I. Lavrik
New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1
Int. J. Mol. Sci. 2021, 22(21), 11336 doi:10.3390/ijms222111336, IF=5.922
- A.S. Filimonov, O.I. Yarovaya, A.V. Zaykovskaya, N.B. Rudometova, D.N. Shcherbakov, V.Yu. Chirkova, D.S. Baev, S.S. Borisevich, O.A. Luzina, O.V. Pyankov, R.A. Maksyutov, N.F. Salakhutdinov
(+)-Usnic Acid and Its Derivatives as Inhibitors of a Wide Spectrum of SARS-CoV-2 Viruses
Viruses 2022, 14(10), 2154 doi:10.3390/v14102154, IF=5.817
- V.P. Nikolin, N.A. Popova, V.I. Kaledin, O.A. Luzina, A.L. Zakharenko, N.F. Salakhutdinov, O.I. Lavrik
The influence of an enamine usnic acid derivative (a tyrosyl-DNA phosphodiesterase 1 inhibitor) on the therapeutic effect of topotecan against transplanted tumors in vivo
Clinical & Experimental Metastasis, 2021, 38, Pp 431-440 doi:10.1007/s10585-021-10113-y, IF=5.15
- D. Pon'kina, S. Kuranov, M. Khvostov, N. Zhukova, Yu. Meshkova, M. Marenina, O. Luzina, T. Tolstikova, N. Salakhutdinov
Hepatoprotective Effect of a New FFAR1 Agonist-N-Alkylated Isobornylamine
Molecules 2023, 28(1), 396; doi:10.3390/molecules28010396, IF=4.927
- D.S. Baev, M.E. Blokhin, V.Yu. Chirkova, S.V. Belenkaya, O.A. Luzina, O.I. Yarovaya, N.F. Salakhutdinov, D.N. Shcherbakov
Triterpenic Acid Amides as Potential Inhibitors of the SARS-CoV-2 Main Protease
Molecules 2023, 28(1), 303 doi:10.3390/molecules28010303, IF=4.927
- S. Kuranov, M. Marenina, D. Ivankin, M. Blokhin, S. Borisov, T. Khomenko, O. Luzina, M. Khvostov, K. Volcho, T. Tolstikova, N. Salakhutdinov
The Study of Hypoglycemic Activity of 7-Terpenylcoumarins
Molecules 2022, 27(24), 8663 doi:10.3390/molecules27248663, IF=4.927
- S. Wang, Ya.V. Zonov, V.M. Karpov, O.A. Luzina, T.V. Mezhenkova
Carbonylation of Polyfluorinated 1-Arylalkan-1-ols and Diols in Superacids
Molecules 2022, 27(24), 8757 doi:10.3390/molecules27248757, IF=4.927
- A.L. Zakharenko, O.A. Luzina, D.N. Sokolov, V.I. Kaledin, V.P. Nikolin, N.A. Popova, J. Patel, O.D. Zakharova, A.A. Chepanova, A. Zafar, J. Reynisson, E. Leung, I.K-H. Leung, K.P. Volcho, N.F. Salakhutdinov, O.I. Lavrik
Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models
European Journal of Medicinal Chemistry, 2019, V. 161, Pages 581-593 doi:10.1016/j.ejmech.2018.10.055, IF=4.833
- N.S. Dyrkheeva, A.S. Filimonov, O.A. Luzina, A.L. Zakharenko, E.S. Ilina, A.A. Malakhova, S.P. Medvedev, J. Reynisson, K.P. Volcho, S.M. Zakian, N.F. Salakhutdinov, O.I. Lavrik
New Hybrid Compounds Combining Fragments of Usnic Acid and Monoterpenoids for Effective Tyrosyl-DNA Phosphodiesterase 1 Inhibition
Biomolecules, 2021, 11(7), 973 doi:10.3390/biom11070973, IF=4.81
- S.O. Kuranov, O.A. Luzina, O. Onopchenko, I. Pishel, S. Zozulya, M. Gureev, N.F. Salakhutdinov, M. Krasavin
Exploring bulky natural and natural-like periphery in the design of p-(benzyloxy)phenylpropionic acid agonists of free fatty acid receptor 1 (GPR40)
Bioorganic Chemistry Volume 99, June 2020, 103830 doi:10.1016/j.bioorg.2020.103830, IF=4.567
- E.D. Gladkova, I.V. Nechepurenko, R.A. Bredikhin, A.A. Chepanova, A.L. Zakharenko, O.A. Luzina, E.S. Ilina, N.S. Dyrkheeva, E.M. Mamontova, R.O. Anarbaev, J. Reynisson, K.P. Volcho, N.F. Salakhutdinov, O.I. Lavrik
The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme
Int. J. Mol. Sci. 2020, 21(19), 7162 doi:10.3390/ijms21197162, IF=4.556
- Yu.N. Antonenko, L.S. Khailova, T.I. Rokitskaya, E.S. Nosikova, P.A. Nazarov, O.A. Luzina, N.F. Salakhutdinov, E.A. Kotova
Mechanism of action of an old antibiotic revisited: Role of calcium ions in protonophoric activity of usnic acid
Biochimica et Biophysica Acta (BBA) - Bioenergetics, V. 1860, N 4, 1 April 2019, Pp 310-316 doi:10.1016/j.bbabio.2019.01.005, IF=4.441
- E.D. Gladkova,A. A. Chepanova,E. S. Ilina,A. L. Zakharenko,J. Reynisson,O. A. Luzina,K. P. Volcho,O. I. Lavrik, N. F. Salakhutdinov
Discovery of Novel Sultone Fused Berberine Derivatives as Promising Tdp1 Inhibitors
Molecules 2021, 26(7), 1945 doi:10.3390/molecules26071945, IF=4.411
- S. Kuranov, O. Luzina, M. Khvostov, D. Baev, D. Kuznetsova, N. Zhukova, P. Vassiliev, A. Kochetkov, T. Tolstikova, N. Salakhutdinov
Bornyl Derivatives of p-(Benzyloxy)Phenylpropionic Acid: In Vivo Evaluation of Antidiabetic Activity
Pharmaceuticals 2020, 13(11), 404 doi:10.3390/ph13110404, IF=4.285
- O. Luzina, A. Filimonov, A. Zakharenko, A. Chepanova, O. Zakharova, E. Ilina, N. Dyrkheeva, G. Likhatskaya, N. Salakhutdinov, O. Lavrik
Usnic Acid Conjugates with Monoterpenoids as Potent Tyrosyl-DNA Phosphodiesterase 1 Inhibitors
Journal of Natural Products, 2020, 83, 8, 2320–2329 doi:10.1021/acs.jnatprod.9b01089, IF=3.779
- A.Zakharenko, O. Luzina, O.Koval, D. Nilov, I. Gushchina, N. Dyrkheeva, V. Svedas, N. Salakhutdinov, O. Lavrik
Tyrosyl-DNA phosphodiesterase 1 inhibitors: usnic acid enamines enhance the cytotoxic effect of camptothecin
J. Nat. Prod., 2016, 79 (11), pp 2961-2967 doi:10.1021/acs.jnatprod.6b00979, IF=3.661
- A.S. Filimonov, A.A. Chepanova, O.A. Luzina, A.L. Zakharenko, O.D. Zakharova, E.S. Ilina, N.S. Dyrkheeva, M.S. Kuprushkin, A.V. Kolotaev, D.S. Khachatryan, J. Patel, I.K. H. Leung, R. Chand, D.M. Ayine-Tora, J. Reynisson, K.P. Volcho, N.F. Salakhutdinov, O.I. Lavrik
New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors
Molecules 2019, 24(20), 3711 doi:10.3390/molecules24203711, IF=3.59
