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N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry
Of the Siberian Branch of Russian Academy of Science

 

Department of Medicinal Chemistry

salahutdinov


Head - Corresponding Member of the Russian Academy of Sciences,
Doctor of Chemical Sciences, Professor
Nariman F. Salakhutdinov

phone +7 (383) 330-97-33,
Fax: +7 (383) 330-97-52,
internal phone: 3-75,
email:This email address is being protected from spambots. You need JavaScript enabled to view it.

Short history

Laboratory of physiologically active substances (up to 2012 – Laboratory of forest chemistry and natural biologically active compounds) was established as a division of the Department of Medical Chemistry, Novosibirsk Institute of Organic Chemistry SB RAS. Its personnel is based on the staff of the laboratory of cationic reactions NIOCh SB RAS (before 2004 – head Prof. V. A. Barkhash). At present, it is a unit equipped with modern scientific instruments and personnel of  high qualification. The staff of the lab has 20 employees, including two full professors and 14 PhD’s.


Current projects

  • RFBR Projects:
    • Creation of a basic foundation for the development of technological methods for the synthesis of physiologically active compounds from the available monoterpenoids using supercritical solvents (11-08-00171-a);
    • Creation of anti-cancer polysulfide compounds PPAR1 inhibitors (11-04-12099-ofi-m-2011);
    • The study of the fundamental laws of interaction of monoterpenoids with aromatic aldehydes to detect antiparkinsonian agents of a new structural type (11-03-00010-a);
    • Identification of the fundamental laws of the reactivity of pinane terpenoids in the presence of acidic crystalline aluminosilicate catalysts to discover new pharmacologically active compounds (10-03-00230-a);
    • The development of selective functionalization methods of (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol at the methyl groups to study the effects of substituents on the antiparkinsonian activity (12-03-31257 mol_a);
    • The reactivity study of carbonyl compounds of monoterpene type in the reactions with different nitrogen-containing derivatives of adamantane to find new anxiolytic agents (12-03-31392 mol_a). Integration projects:
    • A study of genetic and neurophysiological mechanisms of actions of the brain-derived neurotrophic factor and its synthetic agonists);
    • A study of metabolites of marine and plant origin as a scientific basis for the development of important drugs;
    • Integration project of SB RAS on partner basic research No 30 (2012-2013 years) "Development of long-acting form of the neurotoxin to relieve arrhythmia on in vivo model of atrial fibrillation";
    • Search and creation of products for cancer therapy based on modified natural compounds.
  • RAS and SB RAS presidium programmes:
    • The origin of life and the formation of the biosphere (Natural clays as catalysts for prebiotic reactions of chiral compounds);
    • Development of effective anticancer agents based on modified natural triterpene acids (the program "Basic Sciences for Medicine" of SB RAS);
    • Expedition project "Survey of plants of Siberia and Altai as a scientific basis for the development of domestic medicinal and preventive drugs." State contract.
    • "Preclinical studies of TB drugs based on semi-synthetic derivatives of usnic acid" (within the Federal Target Program "Development of the medical and pharmaceutical industry of the Russian Federation for the period up to 2020 and beyond"). 12411.1008799.13.002 (2012).

 

Selected publications

 

  1. Tatyana G. Tolstikova, Alla V. Pavlova, Ekaterina A. Morozova, Tatyana M. Khomenko, Konstantin P. Volcho, Nariman F. Salakhutdinov. The Analgesic Activity of 8-(Trifluoromethyl)-1,2,3,4,5-benzopentathiepine-6-amine and Its Hydrochloride. Letters in Drug Design & Discovery, 2012, 9, 513-516.
  2. Zakharenko A., Sokolov D., Luzina O., Sukhanova M., Khodyreva S., Zakharova O., Salakhutdinov N., Lavrik O. Influence of Usnic Acid and its Derivatives on the Activity of Mammalian Poly(ADP-ribose)polymerase 1 and DNA Polymerase. Medicinal Chemistry, 2012, 8, 883-893.
  3. I. V. Il`ina, V. P. Sivcev, K. P. Volcho, N. F. Salakhutdinov, V. I. Anikeev. The Meerwein-Ponndorf-Verley type reaction in a mixture of supercritical isopropanol/CO2 in a continuous flow reactor in the presence of alumina. J. Supercritical Fluids, 2012, 61, 115–118.
  4. Dmitriy N. Sokolov, Vladimir V. Zarubaev, Anna A. Shtro, Marina P. Polovinka, Olga A. Luzina, Nina I. Komarova, Nariman F. Salakhutdinov, Oleg I. Kiselev. Anti-viral activity of (-)- and (+)-usnic acids and their derivatives against influenza virus A(H1N1)2009. Bioorg. Med. Chem. Letters, 2012, 22, 7060–7064
  5. V. P. Sivcev, K. P. Volcho, N. F. Salakhutdinov, V. I. Anikeev. Transformations of acetophenone and its derivatives in supercritical fluid isopropanol/CO2 in a continuous flow reactor in the presence of alumina. J. of Supercritical Fluids, 2012, 70, 35–39.
  6. Alexander V. Kulikov, Maria A. Tikhonova, Elizabeth A. Kulikova, Konstantin P. Volcho, Tatyana M. Khomenko, Nariman F. Salakhutdinov, Nina K. Popova. A new synthetic varacin analogue, 8-(trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine hydrochloride (TC-2153), decreased hereditary catalepsy and increased the BDNF gene expression in the hippocampus in mice. Psychopharmacology, 2012, 221, 469–478.
  7. Рогачев А. Д., Комарова Н. И., Поздеева А. В., Корчагина Д. В., Васильев В. Г., Салахутдинов Н. Ф., Толстиков Г. А. Взаимодействие некоторых производных гликозидов резвератрола с гипохлоритами в различных средах. Химия Природ. Соедин., 2012, №1, 5-11.
  8. Zakharenko A. L., Salomatina O. V., Sukhanova M. V., Kutuzov M. M., Ilina E. S., Khodyreva S. N., Schreiber V., Salakhutdinov N. F., Lavrik O. I. Glycyrrhetinic acid and its derivatives as inhibitors of poly(ADP-ribose)polymerases 1 and 2, apurinic/apyrimidinic endonuclease 1 and DNA polymerase. Biopolymers and Cell, 2012, 28, 223–228.
  9. И. В. Нечепуренко, Н. И. Комарова, В. Г. Васильев, Н. Ф. Салахутдинов. Синтез аналогов берберинбромида, содержащих фрагмент третичных амидов уксусной кислоты в 9-О-положениии. Химия Природ. Соедин., 2012, №6, 924-929.
  10. Ardashov O. V., Pavlova A. V., Il’ina I. V., Morozova E. A., Korchagina D. V., Karpova E. V., Volcho K. P., Tolstikova T. G., Salakhutdinov N. F. Highly Potent Activity of (1R,2R,6S)-3-Methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in Animal Models of Parkinson’s Disease. J. Med. Chem., 2011, 54, 3866-3874.
  11. И. В. Нечепуренко, У. А. Боярских, Н. И. Комарова, М. П. Половинка, М. Л. Филипенко, Г. И. Лифшиц, Н. Ф. Салахутдинов, Г. А. Толстиков. Влияние берберина и его бром- и иодпроизводных на уровень экспрессии гена рецептора ЛПНП в клетках HepG2. Доклады АН, 2011, 439, 346–350.
  12. Ekaterina A. Koneva, Evgeniy V. Suslov, Dina V. Korchagina, Alexander M. Genaev, Konstantin P. Volcho, Nariman F. Salakhutdinov. Catalytic asymmetric addition of diethylzinc to benzaldehyde using ?-pinene-derived ligands. The Open Catalysis Journal, 2011, 4, 107-112.
  13. Irina V. Il’ina, Konstantin P. Volcho, Oksana S. Mikhalchenko, Dina V. Korchagina and Nariman F. Salakhutdinov. Reactions of Verbenol Epoxide with Aromatic Aldehydes Containing Hydroxy or Methoxy Groups in the Presence of Montmorillonite Clay. Helvetica Chimica Acta, 2011, 94, 502-513.
  14. Ardashov O. V., Zarubaev V. V., Shtro A. A., Korchagina D. V., Volcho K. P., Salakhutdinov N. F., Kiselev O. I. Antiviral activity of 3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol and its derivatives against influenza A(H1N1)2009 virus. Letters in Drug Design & Discovery, 2011, 8, 375-380.
  15. Logashenko E.B., Salomatina O.V., Markov A.V., Korchagina D.V., Salakhutdinov N.F., Tolstikov G.A., Vlassov V.V., Zenkova M.A. Synthesis and Pro-Apoptotic Activity of Novel Glycyrrhetinic Acid Derivatives. ChemBioChem, 2011, 12, 784-794.
  16. D. N. Sokolov, O. A. Luzina, D. V. Korchagina, M. P. Polovinka, N. F. Salakhutdinov. Reaction of (+)-usninic acid and several of its derivatives with diazomethane. Chemistry of Natural Compounds, 2011, 47, 708-712.
  17. И. В. Нечепуренко, М. П. Половинка, Н. И Комарова, Н. Ф. Салахутдинов, Г. А. Толстиков. Способ получения пакистанамина и берберина хлорида из Berberis sibirica. Патент РФ, 2010, RU2423992 C1.
  18. Salomatina O.V., Logashenko E.B., Korchagina D.V., Salakhutdinov N.F., Tolstikov G.A., Vlassov V.V., Zenkova M.A. Synthesis and Biological Activity of Novel Glycyrrhetic Acid Derivatives. Doklady Chemistry, 2010, 430, 35–38.
  19. Саломатина О. В., Салахутдинов Н. Ф., Толстиков Г. А., Логашенко Е. Б., Зенкова М. А., Власов В. В. Противоопухолевое средство тритерпеновой природы, полученное путем модификации глицирретовой кислоты. Патент РФ № 2401273, 2010.
  20. И. В. Нечепуренко, Н. Ф. Салахутдинов, Г. А. Толстиков. Берберин: химия и биологическая активность. Химия в интересах устойчивого развития, 2010, 18, 1-23.
  21. Толстикова Т. Г., Павлова А. В., Морозова Е. А., Ардашов О. В., Ильина И. В., Волчо К. П., Салахутдинов Н. Ф., Толстиков Г. А. Высокоэффективное противопаркинсоническое средство нового структурного типа. Доклады АН. Физиология, 2010, 435, 708–710.
  22. Толстикова Т. Г., Павлова А. В., Долгих М. П., Ильина И. В., Ардашов О. В., Волчо К. П., Салахутдинов Н. Ф., Толстиков Г. А. Новый высокоэффективный противосудорожный агент – (4S,5R,6R)-пара-мента-1,8-диен-5,6-диол. Доклады АН. Физиология, 2009, 429, 139–141.
  23. Suslov E. V., Volcho K. P., Salakhutdinov N. F. Basic zeolites and mesoporous materials in Knoevenagel and Michael reactions. Handbook of Zeolites: Structure, Properties and Applications. Ed. T. W. Wong. Hauppauge: Nova Science Publishers, 2009. ISBN 9781607410461, 676 p.
  24. И. В. Нечепуренко, Н. И. Комарова, Ю. В. Герасимова, В. В. Коваль, М. П. Половинка, Д. В. Корчагина, Н. Ф. Салахутдинов. Изучение структуры олигомерных проантоцианидинов корней Hedysarum theinum методами тиолиза и МС MALDI-TOF. Химия Природ. Соедин., 2009, №1, 30-36.
  25. Суслов Е. В., Волчо К. П., Покровский А. Г., Салахутдинов Н. Ф. Ингибитор репродукции вируса иммунодефицита. Патент РФ №2007139397б 2009.
  26. Ilina I. V., Suslov E. V., Khomenko T. M., Korchagina D. V., Volcho K. P., Salakhutdinov N. F. Natural montmorillonite clay as prebiotic catalyst. Paleontological Journal, 2009, 43, 958–964.
  27. T. M. Khomenko, T. G. Tolstikova, A. V. Bolkunov, M. P. Dolgikh, A. V. Pavlova, D. V. Korchagina, K. P. Volcho, N. F. Salakhutdinov. 8-(Trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine: Novel Aminobenzopentathiepine having In Vivo Anticonvulsant and Anxiolytic Activities. Letters in Drug Design & Discovery, 2009, 6, 464-467.
  28. Ekaterina A. Koneva, Konstantin P. Volcho, Yuri V. Gatilov, Dina V. Korchagina, Georgi E. Salnikov, Nariman F. Salakhutdinov. Synthesis of the Derivatives of the Optically Active b-Amino Acids from (+)-2-Carene. Helvetica Chimica Acta, 2008, 91, 1849-1856.
  29. K. P. Volcho, N. F. Salakhutdinov. Transformations of Terpenoids on Acidic Clays. Mini Reviews in Organic Chemistry, 2008, 5, 345-354.
  30. Хоменко Т. М., Волчо К. П., Комарова Н. И., Салахутдинов Н. Ф. Эффективный способ получения эзомепразола с использованием комплекса хиральных лигандов. ЖОрХ, 2008, 44, 126–129.
  31. Ильина И. В., Волчо К. П., Салахутдинов Н. Ф. Кислотно-катализируемые превращения терпеноидов пинанового ряда – новые возможности. ЖОрХ, 2008, 44, 11–31.
  32. Конева Е. А., Хоменко Т. М., Курбакова С. Ю., Комарова Н. И., Корчагина Д. В., Волчо К. П., Салахутдинов Н. Ф., Толстиков А. Г., Толстиков Г. А. Получение оптически активного омепразола с использованием каталитических комплексов ионов ванадия с хиральными основаниями Шиффа. Изв. РАН. Сер. Хим., 2008, №8, 1648-1653.
  33. Irina V. Il’ina, Konstantin P. Volcho, Dina V. Korchagina, Vladimir A. Barkhash, Nariman F. Salakhutdinov. Reactions of Allyl Alcohols of the Pinane Series and of Their Epoxides in the Presence of Montmorillonite Clay. Helvetica Chimica Acta, 2007, 90, 353-368.
  34. Salomatina O. V., Kuznetsova Т. G., Korchagina D. V., Paukshtis E. A., Moroz E. M., Volcho K. P., Barkhash V. A., Salakhutdinov N. F. Effects of the properties of ZrO2/SO4 solid-phase catalysts on the products of (+)-limonene diepoxides transformation and reaction mechanism. J. Mol. Cat. A: Chemical, 2007, 269, 72-80.
  35. Саломатина О. В., Салахутдинов Н. Ф., Толстиков Г. А., Логашенко Е. Б., Зенкова М. А., Власов В. В. Противоопухолевое средство тритерпеновой природы. Патент РФ № 2393165, 2008.

 

Research areas:

Research areas:



The major scientific trends

 

  • Development of new leading compounds in the most popular therapeutic areas – oncology, cardiovascular diseases, neurodegenerative diseases, analgesics, and infectious disease.
  • Reactivity study of monoterpenoids in the presence of heterogeneous catalysts. Development of effective methods of catalytic conversions of organic compounds in supercritical fluids.
  • Development of methods for the stereoselective synthesis, including new catalytically asymmetric systems.
  • Directed chemical modification of metabolites of plant and animal origin in order to obtain new semisynthetic derivatives of valuable biological properties.
  • The study of Siberian and Altai plants as a scientific basis for the development of Russian medical and preventive medications.

 

Main scientific results

 

  • A new promising agent for the treatment of Parkinson's disease, who is at the stage of pre-clinical trials, was developed. Based on polysulfur compounds, an agent having high antidepressant activity, superior to that of some commercial products, was created. Compounds perspective for the development of a new structural type of analgesics, anticonvulsants were found.
  • As a result of the reactivity study of the usnic acid which is a metabolite of a number of lichens, new highly active anti-TB and anti-influenza agents have been developed.
  • New catalytic systems for the asymmetric oxidation of sulfides to sulfoxides and asymmetric chiral addition of diethylzink to aldehydes were created. Patent collision-free methods of asymmetric synthesis of the modern anti-ulcer drug "Esomeprazole" with the use of original catalytic systems were developed.
  • As a result of phytochemical studies it was found that the roots of barberry Berberis sibirica Pall, both natural and introduced populations growing in Russia, are a practical source of isoquinoline alkaloid berberine. A technique which allows the isolation of berberine chloride with the yield up to 0.62% on the dry weight of roots was developed and patented. A review summarizing the reactions of berberine and its hydrogenated derivatives, as well as information on the biological activity of berberine and some of its derivatives was published. Methods of the direct introduction of bromine and iodine in the molecule of berberine were developed in first time.
  • New semisynthetic derivative of glycyrrhetic acid, methyl soloksolon, having anticancer and anti-inflammatory activities was obtained. Its preclinical in vitro and in vivo tests have shown a high potential of this compound as a high-performance low-toxic agent in the drug development.
  • Chemical transformations of stilbene glycosides, resveratroloside and pinostilbenoside  were performed and their derivatives were obtained. It was found that resveratroloside had cardioprotective properties comparable to those of resveratrol.

 

List of priority investigations

 

  • Scientific basis of isolation technologies of plant metabolites of Siberian flora as a raw material source promising synthons for medicinal chemistry and pharmaceutical industries.
  • Synthetic transformation of plant alkaloids, terpenoids and coumarins. The total synthesis of the substances of high pharmacological importance

 







STAFF


Staff

Employee Position Room Phone Phone in. email Publications
by years
1 Salakhutdinov Nariman Faridovich Head of Depart. (Doct. Chem.) 310 НТК 330-97-33 3-75 This email address is being protected from spambots. You need JavaScript enabled to view it.
2 Volcho Konstantin Petrovich Chief Researcher (Doct. Chem.) 129, 311 НТК 330-88-70 3-96, 3-01 This email address is being protected from spambots. You need JavaScript enabled to view it.
3 Lavrik Olga Ivanovna Chief Researcher (Doct. Chem.)
4 Luzina Olga Anatolievna Leading Researcher (Doct. Chem) 204 330-88-70 2-57, 2-21 This email address is being protected from spambots. You need JavaScript enabled to view it.
5 Yarovaya Olga Ivanovna Leading Researcher (Doct. Chem) 205 330-88-70 2-25 This email address is being protected from spambots. You need JavaScript enabled to view it.
6 Ardashov Oleg Vasilievich Senior Researcher (Cand. Chem.) 129 330-88-70 3-96 This email address is being protected from spambots. You need JavaScript enabled to view it.
7 Il'ina Irina Viktorovna Senior Researcher (Cand. Chem.) 129 330-88-70 3-96 This email address is being protected from spambots. You need JavaScript enabled to view it.
8 Rogachev Artem Dmitrievich Senior Researcher (Cand. Chem.) 330 330-97-47 2-36 This email address is being protected from spambots. You need JavaScript enabled to view it.
9 Salomatina Oksana Vladimirovna Senior Researcher (Cand. Chem.) П-042 330-88-70 2-55 This email address is being protected from spambots. You need JavaScript enabled to view it.
10 Sokolova Anastasiya Sergeevna Senior Researcher (Cand. Chem.) 205 330-88-70 2-25 This email address is being protected from spambots. You need JavaScript enabled to view it.
11 Khomenko Tatyana Mikhailovna Senior Researcher (Cand. Chem.) 103 330-88-70 4-46 This email address is being protected from spambots. You need JavaScript enabled to view it.
12 Dyrkheeva Nadezda Sergeevna Researcher (Cand. Chem.)
13 Zakharenko Alexandra Dmitrievna Researcher (Cand. Chem.)
14 Laev Sergey Sergeevich Researcher (Cand. Chem.) 409 НТК 2-38 This email address is being protected from spambots. You need JavaScript enabled to view it.
15 Nechepurenko Ivan Vasilievich Researcher (Cand. Chem.) 330 330-88-70; 8-983-124-30-49 2-36 This email address is being protected from spambots. You need JavaScript enabled to view it., This email address is being protected from spambots. You need JavaScript enabled to view it.
16 Patrusheva Oxana Stanislavovna Researcher (Cand. Chem.) 129 330-88-70 3-96 This email address is being protected from spambots. You need JavaScript enabled to view it.
17 Popadyuk Irina Igorevna Researcher (Cand. Chem.) П-042 330-88-70 2-55 This email address is being protected from spambots. You need JavaScript enabled to view it.
18 Fomenko Vladislav Viktorovich Researcher (Cand. Chem.) 302 330-97-47 2-02 This email address is being protected from spambots. You need JavaScript enabled to view it.
19 Komarova Nina Ivanovna Leading Engineer 308 330-97-47 2-84 This email address is being protected from spambots. You need JavaScript enabled to view it.
20 Kurbakova Svetlana Yurievna Leading Engineer 129 330-88-70 3-96 This email address is being protected from spambots. You need JavaScript enabled to view it.
21 Mainagashev Ilia Yakovlevich Leading Engineer 330 330-88-70 2-36 This email address is being protected from spambots. You need JavaScript enabled to view it.
22 Blokhin Mikhail Evgenievich engineer 204 330-88-70 2-21 This email address is being protected from spambots. You need JavaScript enabled to view it.
23 Vyazovkin Ivan Vladimirovich Leading Engineer
Students
24 Baranova Darya Vitalievna laboratory assistant 205 330-88-70 2-25 This email address is being protected from spambots. You need JavaScript enabled to view it.
25 Okhina Alina Aleksandrovna laboratory assistant 330 330-88-70 2-36
26 Putilova Valentina Pavlovna laboratory assistant 205 330-88-70 2-25 This email address is being protected from spambots. You need JavaScript enabled to view it.
27 Mordvinova Ekaterina Borisovna laboratory assistant
PHD Students
28 Ivankin Dmitry Igorevich engineer 302, 330 330-97-47 2-02, 2-36 This email address is being protected from spambots. You need JavaScript enabled to view it.

PUBLICATIONS

Publications over the past years

 

Laboratory staff publications (DB NIOCh)

Reviews, Articles


2020
  1. O. Luzina, A. Filimonov, A. Zakharenko, A. Chepanova, O. Zakharova, E. Ilina, N. Dyrkheeva, G. Likhatskaya, N. Salakhutdinov, O. Lavrik
    Usnic Acid Conjugates with Monoterpenoids as Potent Tyrosyl-DNA Phosphodiesterase 1 Inhibitors
    Journal of Natural Products, Articles ASAP (Article), Publication Date (Web):July 28, 2020 doi:10.1021/acs.jnatprod.9b01089, IF=3.779
  2. V.V. Chernyshov, O.I. Yarovaya, R.Yu. Peshkov, N.F. Salakhutdinov
    Synthesis of cyclic D-(+)-camphoric acid imides and study of their antiviral activity
    Chemistry of Heterocyclic Compounds, Published: 22 July 2020 doi:10.1007/s10593-020-02728-y, IF=1.491
  3. I.V. Il'ina, N.S. Dyrkheeva, A.L. Zakharenko, A.Yu. Sidorenko, N.S. Li-Zhulanov, D.V. Korchagina, R. Chand, D.M. Ayine-Tora, A.A. Chepanova, O.D. Zakharova, E.S. Ilina, J. Reynisson, A.A. Malakhova, S.P. Medvedev, S.M. Zakian, K.P. Volcho, N.F. Salakhutdinov, O.I. Lavrik
    Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1
    Molecules 2020, 25(15), 3496 doi:10.3390/molecules25153496, IF=3.267
  4. E.A. Kulikova, O.S. Kozhevnikova, A.V. Kulikov, N.G. Kolosova, T.M. Khomenko, K.P. Volcho, N.F. Salakhutdinov, D.V. Telegina
    Alterations of STEP46 and STEP61 Expression in the Rat Retina with Age and AMD-Like Retinopathy Development
    Int. J. Mol. Sci. 2020, 21(15), 5182 doi:10.3390/ijms21155182, IF=4.556
  5. A.Yu. Sidorenko, A.V. Kravtsova, P. Maki-Arvela, A. Aho, T. Sandberg, I.V. Il'ina, N.S. Li-Zhulanov, D.V. Korchagina, K.P. Volcho, N.F. Salakhutdinov, D.Yu. Murzin, V.E. Agabekov
    Synthesis of isobenzofuran derivatives from renewable 2-carene over halloysite nanotubes
    Molecular Catalysis, 2020, V. 490, 110974 doi:10.1016/j.mcat.2020.110974, IF=3.687
  6. S.O. Kuranov, O.A. Luzina, O. Onopchenko, I. Pishel, S. Zozulya, M. Gureev, N.F. Salakhutdinov, M. Krasavin
    Exploring bulky natural and natural-like periphery in the design of p-(benzyloxy)phenylpropionic acid agonists of free fatty acid receptor 1 (GPR40)
    Bioorganic Chemistry Volume 99, June 2020, 103830 doi:10.1016/j.bioorg.2020.103830, IF=4.567
  7. Features of lipidomic profile of erythrocyte membranes and blood serum in patients with fatty liver disease/ Kkruchinina M.V., Parulikova M.V., Kurilovich S.A., Gromov A.A., Shashkov M.V., Sokolova A.S., Kruchinin V.N.// doi:10.15372/ATER20200202
  8. A.V. Markov, A.V. Sen’kova, O.V. Salomatina, E.B. Logashenko, D.V. Korchagina, N.F. Salakhutdinov, M.A. Zenkova
    Trioxolone Methyl, a Novel Cyano Enone-Bearing 18βH-Glycyrrhetinic Acid Derivative, Ameliorates Dextran Sulphate Sodium-Induced Colitis in Mice
    Molecules 2020, 25(10), 2406 doi:10.3390/molecules25102406, IF=3.267
  9. A.V. Markov, Al.V. Sen'kova, I.I. Popadyuk, O.V. Salomatina, E.B. Logashenko, N.I. Komarova, A.A. Ilyina, N.F. Salakhutdinov, M.A. Zenkova
    Novel 3'-Substituted-1'2',4'-Oxadiazole Derivatives of 18βH-Glycyrrhetinic Acid and Their O-Acylated Amidoximes: Synthesis and Evaluation of Antitumor and Anti-Inflammatory Potential In Vitro and In Vivo
    Int. J. Mol. Sci. 2020, 21(10), 3511 doi:10.3390/ijms21103511, IF=4.556
  10. A. Sidorenko, N. Li-Zhulanov, P. Mäki-Arvela, T. Sandberg, A. Kravtsova, A. Peixoto, C. Freire, K. Volcho, N. Salakhutdinov, V. Agabekov, D. Murzin
    Stereoselectivity inversion by water addition in the -SO3H catalyzed tandem Prins-Ritter reaction for synthesis of 4-amidotetrahydropyran derivatives
    ChemCatChem, 2020, V. 12, N. 9, Pp 2605- 2609 doi:10.1002/cctc.202000070, IF=4.853
  11. M. Laluc, P. Maki-Arvela, A.F. Peixoto, N. Li-Zhulanov, T. Sandberg, N.F. Salakhutdinov, K. Volcho, C. Freire, A.Yu. Sidorenko, D.Yu. Murzin
    Catalytic synthesis of bioactive 2H-chromene alcohols from (-)-isopulegol and acetone on sulfonated clays
    Reaction Kinetics, Mechanisms and Catalysis, 2020, V. 129, N 2, Pp 627-644 doi:10.1007/s11144-020-01740-9, IF=1.52
  12. I. Il'ina, E. Morozova, A. Pavlova, D. Korchagina, T. Tolstikova, K. Volcho, N. Salakhutdinov
    Synthesis and analgesic activity of aliphatic ketones-derived chiral hexahydro-2H-chromenes
    Medicinal Chemistry Research, 2020, V. 29, N 4, pp 738-747 doi:10.1007/s00044-020-02518-3, IF=1.783
  13. Yu.S. Demidova, E.S. Mozhaitsev, A.A. Munkuev, E.V. Suslov, A.A. Saraev, K.P. Volcho, N.F. Salakhutdinov, I.L. Simakova, D.Yu. Murzin
    Monoterpenoid Oximes Hydrogenation Over Platinum Catalysts
    Topics in Catalysis, 2020, V. 63, N 1-2, pages187-195 doi:10.1007/s11244-020-01234-x, IF=2.406
  14. Yu.S. Demidova, E.S. Mozhaitsev, A.A. Munkuev, E.V. Suslov, A.A. Saraev, K.P. Volcho, N.F. Salakhutdinov, I.L. Simakova, D.Yu. Murzin
    Monoterpenoid Oximes Hydrogenation Over Platinum Catalysts
    Topics in Catalysis, 2020, V. 63, N 1-2, Pp 187-195 doi:10.1007/s11244-020-01234-x, IF=2.406
  15. A.A. Kotlyarova, K.Yu. Ponomarev, E.A. Morozova, D.V. Korchagina, E.V. Suslov, A.V. Pavlova, T.G. Tolstikova, K.P. Volcho, N.F. Salakhutdinov
    The effect of 3,7-diazabicyclo[3.3.1]nonanes containing monoterpenoid moieties on the physical activity of mice
    Journal of research in pharmacy, 2020, V. 24, N 2, Pp 196-204 doi:10.35333/jrp.2020.136
  16. A.D. Rogachev, D.V. Trebushat, A.N. Kudryashov, A.G. Pokrovsky
    Study of Sirolimus Adsorption and Preparation of Its Samples in Methanol, Acetonitrile and Their Mixtures with Water for HPLC-MS/MS Analysis
    Chromatographia, 2020, V. 83, N 2, pp 299-304 doi:10.1007/s10337-019-03835-5, IF=1.596
  17. V.V. Chernyshov, O.I. Yarovaya, D.S. Fadeev, Yu.V. Gatilov, Ya.L. Esaulkova, A.S. Muryleva, K.O. Sinegubova, V.V. Zarubaev, N.F. Salakhutdinov
    Single-stage synthesis of heterocyclic alkaloid-like compounds from (+)-camphoric acid and their antiviral activity
    Molecular Diversity, 2020, V. 24, N 1, Pp 61-67 doi:10.1007/s11030-019-09932-9, IF=2.013
  18. Analytical Control of Impurities and Active Components in (-)-Isopulegol Derivative - Highly Potent Analgesic Agent/ Lastovka A.V, Fadeeva V.P., Il'ina I.V., Salakhutdinov N.F.// Pharmaceutical Chemistry Journal doi:10.1007/s11094-020-02176-0, IF=0.538
  19. T. M. Khomenko , A. L. Zakharenko , A. A. Chepanova , E. S. Ilina , O. D. Zakharova , V. I. Kaledin , V. P. Nikolin , N. A. Popova , D. V. Korchagina , J. Reynisson , R. Chand , D.l M. Ayine-Tora , J. Patel , I. K. H. Leung , K. P. Volcho , N. F. Salakhutdinov,O I. Lavrik
    Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy
    Int. J. Mol. Sci. 2020, 21(1), 126. This article belongs to the Special Issue Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach) doi:10.3390/ijms21010126, IF=4.556
  20. E.M. Mamontova, A.L. Zakharenko, O.D. Zakharova, N.S. Dyrkheeva, K.P. Volcho, J. Reynisson, H.J. Arabshahi, N.F. Salakhutdinov, O.I. Lavrik
    Identification of novel inhibitors for the tyrosyl-DNA-phosphodiesterase 1 (Tdp1) mutant SCAN1 using virtual screening
    Bioorganic & Medicinal Chemistry, 2020, V. 28, N 1, 115234 doi:10.1016/j.bmc.2019.115234, IF=3.073
  21. I. Il'ina, E. Morozova, D. Korсhagina, K. Volсho, T. Tolstikova, N. Salakhutdinov
    Synthesis and Analgesic Activity of Monoterpenoid Aldehyde-derived Hydro-2H-chromeneols
    Letters in Drug Design & Discovery, 2020, V. 17, N 1, Pp 68-78 doi:10.2174/1570180816666181114131220, IF=1.169
  22. A.A. Okhina, A.D. Rogachev, O.I. Yarovaya, M.V. Khvostov, T.G. Tolstikova, A.G. Pokrovsky, V.A. Khazanov, N.F. Salakhutdinov
    Development and validation of an LC-MS/MS method for the quantitative analysis of the anti-influenza agent camphecene in rat plasma and its application to study the blood-to-plasma distribution of the agent
    Journal of Pharmaceutical and Biomedical Analysis, 2020, V. 180, 113039 doi:10.1016/j.jpba.2019.113039, IF=3.209

2019
  1. Yu.S. Demidova, I.L. Simakova, M. Estrada, S. Beloshapkin, E.V. Suslov, K.P. Volcho, N.F. Salakhutdinov, A. Simakov, D.Yu. Murzin
    One-Pot Myrtenol Amination over Au, Au-Pd and Pd Nanoparticles Supported on Alumina
    Catalysis Letters, 2019, V. 149, N 12, pp 3454-3464 doi:10.1007/s10562-019-02958-6, IF=2.371
  2. A.Yu.Sidorenko,A.V.Kravtsova,I.V.Il'ina,J.Warna,D.V.Korchagina,Yu.V.Gatilov,K.P.Volcho,N.F.Salakhutdinov,D.Yu.Murzin, V.E.Agabekov
    Clay nanotubes catalyzed solvent-free synthesis of octahydro-2H-chromenols with pharmaceutical potential from (-)-isopulegol and ketones
    Journal of Catalysis, 2019, V. 380, Pp 145-152 doi:10.1016/j.jcat.2019.10.015, IF=7.723
  3. V.V. Chernyshov, Y.V. Gatilov, O.I. Yarovaya, I.P. Koskin, S.S. Yarovoy, K.A. Brylev, N.F. Salakhutdinov
    The first example of the stereoselective synthesis and crystal structure of a spirobi­cyclo­quinazolinone based on (–)-fenchone and anthranilamide
    Acta Crystallographica Section C, V. C75, Part 12, Pp 1675-1680 doi:10.1107/S2053229619015766, IF=0.93
  4. A. Kulikov, N. Sinyakova, E. Kulikova, T. Khomenko, N. Salakhutdinov, V. Kulikov, K. Volcho
    Effects of Acute and Chronic Treatment of Novel Psychotropic Drug, 8- (Trifluoromethyl)-1, 2, 3, 4, 5-benzopentathiepin-6-amine Hydrochloride (TC-2153), on the Behavior of Zebrafish (Danio Rerio): A Comparison with Fluoxetine
    Letters in Drug Design & Discovery, 2019, V.16, N 12, Pp.1321-1328 doi:10.2174/1570180816666190221162952, IF=0.953
  5. O.I. Yarovaya, A.S. Sokolova, I.Ya. Mainagashev, A.S. Volobueva, K. Lantsev, S.S. Borisevich, A.A. Shtro, V.V. Zarubaev, N.F. Salakhutdinov
    Synthesis and structure-activity relationships of novel camphecene analogues as anti-influenza agents
    Bioorganic & Medicinal Chemistry Letters, 1019, V. 29, N 23, 126745 doi:10.1016/j.bmcl.2019.126745, IF=2.447
  6. A. V.Lastovka,A. D.Rogachev,I. V.Il'ina,A.Kabir,K.P.Volcho,V. P.Fadeeva,A.G.Pokrovsky,N. F.Salakhutdinov,K. G.Furtonc
    Comparison of dried matrix spots and fabric phase sorptive extraction methods for quantitation of highly potent analgesic activity agent (2R,4aR,7R,8aR)-4,7-dimethyl-2-(thiophen-2-yl)octahydro-2H-chromen-4-ol in rat whole blood and plasma using LC–MS/MS
    Journal of Chromatography B, 2019, V. 1132, Art. Number 121813 doi:10.1016/j.jchromb.2019.121813, IF=2.789
  7. M.V. Kruchinina, A.A. Gromov, Ya.I. Prudnikova, S.A. Kurilovich, V.N. Kruchinin, V.M. Generalov, M.V. Shashkov, A.S. Sokolova, I.N. Yakovina, N.A. Bannova, G.V. Shuvalov
    Electrical and viscoelastic parameters of erythrocytes in combination with the fatty acid profile of their membranes and serum as potentialbiomarkers for the diagnosis of colorectal cancer
    UNITED EUROPEAN GASTROENTEROLOGY JOURNAL, 2019, V. 7, N S8, P. 387 (27th United European Gastroenterology Week Barselona 2019) doi:10.1177/2050640619854671, IF=3.453
  8. N. Li-Zhulanov, P. Maki-Arvela, M. Laluc, A.F. Peixoto, E. Kholkina, T. Sandberg, A. Aho, K. Volcho, N. Salakhutdinov, C. Freire, A.Yu. Sidorenko, D.Yu. Murzin
    Prins cyclization of (-)-isopulegol with benzaldehyde for production of chromenols over organosulfonic clays
    Molecular Catalysis, 2019, V. 478, 110569 doi:10.1016/j.mcat.2019.110569, IF=2.937
  9. O.I. Artyushin, Al.A. Moiseeva, V.V. Zarubaev, Al.V. Slita, A.V. Galochkina, A.A. Muryleva, S.S. Borisevich, O.I. Yarovaya, N.F. Salakhutdinov, V.K. Brel
    Synthesis of Camphecene and Cytisine Conjugates Using Click Chemistry Methodology and Study of Their Antiviral Activity
    Chemistry & Biodiversity, 2019, V. 16, N 11, e1900340 doi:10.1002/cbdv.201900340, IF=1.449
  10. Effective Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 Based on Monoterpenoids as Potential Agents for Antitumor Therapy/ A.A. Chepanova, N.S. Li-Zhulanov, A.S. Sukhikh, A. Zafar, J. Reynisson, A.L. Zakharenko, O.D. Zakharova, D.V. Korchagina, K.P. Volcho, N.F. Salakhutdinov, O.I. Lavrik// Russian Journal of Bioorganic Chemistry, 2019, Vol. 45, No. 6, pp. 647-655. doi:10.1134/S1068162019060104, IF=0.794
  11. Studying dependences between the chemotype structure of some natural compounds and the spectrum of their targeted activities correlated with the hypoglycemic effect/ P.M. Vasilyev, O.A. Luzina, D.A. Babkov, D.T. Appazova, N.F. Salakhutdinov, A.A. Spasov// J Struct Chem., 2019, V. 60, N 11, Pp 1827-1832 doi:10.1134/S0022476619110179, IF=0.541
  12. A.S. Filimonov, A.A. Chepanova, O.A. Luzina, A.L. Zakharenko, O.D. Zakharova, E.S. Ilina, N.S. Dyrkheeva, M.S. Kuprushkin, A.V. Kolotaev, D.S. Khachatryan, J. Patel, I.K. H. Leung, R. Chand, D.M. Ayine-Tora, J. Reynisson, K.P. Volcho, N.F. Salakhutdinov, O.I. Lavrik
    New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors
    Molecules 2019, 24(20), 3711 doi:10.3390/molecules24203711, IF=3.59
  13. O.V. Ardashov, A.V. Pavlova, A.K. Mahato, Yu. Sidorova, E.A. Morozova, D.V. Korchagina, G.E. Salnikov, A.M. Genaev, O.S. Patrusheva, N. Li-Zhulanov, T.G. Tolstikova, K.P. Volcho, N. Salakhutdinov
    A novel small molecule supports the survival of cultured dopamine neurons and may restore the dopaminergic innervation of the brain in the MPTP mouse model of Parkinson's disease
    ACS Chemical Neuroscience, 2019, V. 10, N 10, Pp 4337-4349 doi:10.1021/acschemneuro.9b00396, IF=3.861
  14. M.F. Kasakin, A.D. Rogachev, E.V. Predtechenskaya, V.J. Zaigraev, V.V. Koval, A.G. Pokrovsky
    Targeted metabolomics approach for identification of relapsing–remitting multiple sclerosis markers and evaluation of diagnostic models
    Med. Chem. Commun., 2019, N. 10, 1803-1809 doi:10.1039/C9MD00253G, IF=2.394
  15. A.V. Markov, A.E. Kel, O.V. Salomatina, N.F. Salakhutdinov, M.A. Zenkova, E.B. Logashenko
    Deep insights into the response of human cervical carcinoma cells to a new cyano enone-bearing triterpenoid soloxolone methyl: A transcriptome analysis
    Oncotarget, 2019, V. 10, N 51, Pp 5267-5297 doi:10.18632/oncotarget.27085
  16. E. Kulikova, N. Khotskin, N. Illarionova, I. Sorokin, K. Volcho, A. Kulikov
    The antidepressant effect of STEP inhibitor (TC-2153) and its influence on the serotoninergic 5-HT2A receptors in the brain
    IBRO Reports, V. 6, Supplement, September 2019, Page S492. P32.59 doi:10.1016/j.ibror.2019.07.1544
  17. A. Kulikov, V. Moskaliuk, R. Kozhemyakina, D. Bazovkina, E. Terenina, K. Volcho, V. Naumenko, E. Kulikova
    Effects of drug TC-2153 on the behavior and striatal-enriched tyrosine protein phosphatase in the brain of rats selectively bred for high and low aggression towards humans
    IBRO Reports, 2019, V. 6, Supplement, Page S115 doi:10.1016/j.ibror.2019.07.368
  18. K. Kovaleva, O. Oleshko, E. Mamontova, O. Yarovaya, O. Zakharova, A. Zakharenko, A. Kononova, N. Dyrkheeva, S. Cheresiz, A. Pokrovsky, O. Lavrik, N. Salakhutdinov
    Dehydroabietylamine Ureas and Thioureas as Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Enhance the Antitumor Effect of Temozolomide on Glioblastoma Cells
    Journal of Natural Products, 2019, V. 82, N 9, Pp 2443-2450 doi:10.1021/acs.jnatprod.8b01095, IF=4.256
  19. М.В. Кручинина, А.В. Азгалдян, И.О. Светлова, М.В. Шашков, А.С. Соколова, В.Н. Кручинин
    Особенности состава жирных кислот сыворотки крови и мембран эритроцитов у пациентов с воспалительными заболеваниями кишечника (пилотное исследование)
    Современные проблемы науки и образования. 2019. № 3. С. 127. doi:10.17513/spno.28868
  20. Synthesis and Hypoglycemic Activity of Aryl(Hetaryl)Propenoic Cyanopyrrolidine Amides/ S. O. Kuranov, M. E. Blokhin, S. A. Borisov, M. V. Khvostov, O. A. Luzina, N. F. Salakhutdinov// Russian Journal of Bioorganic Chemistry, 2019, V. 45, N 5, pp 374-380 doi:10.1134/S1068162019050078, IF=0.794
  21. K. Volcho, A. Zakharenko, O. Luzina, T. Khomenko, E. Suslov, O. Salomatina, O. Zakharova, N. Li-Zhulanov, J. Reynisson, O. Lavrik, N. Salakhutdinov
    Tdp1 Inhibition as a Promising Approach to New Anticancer Drugs
    Proceedings 2019, 22(1), 35 (This article belongs to the Proceedings of The Molecules Medicinal Chemistry Symposium-Challenges in Drug Discovery Barcelona, Spain | 15-17 May 2019) doi:10.3390/proceedings2019022035
  22. A.V. Markov, V.O. Babich, I.I. Popadyuk, O.V. Salomatina, E.B. Logashenko, N.F. Salakhutdinov, M.A. Zenkova
    Novel Derivatives of Deoxycholic Acid Bearing Linear Aliphatic Diamine and Aminoalcohol Moieties and their Cyclic Analogs at the C3 Position: Synthesis and Evaluation of Their In Vitro Antitumor Potential
    Molecules 2019, 24(14), 2644 doi:10.3390/molecules24142644, IF=3.59
  23. A.A. Chepanova, E.S. Mozhaitsev, A.A. Munkuev, E.V. Suslov, D.V. Korchagina, O.D. Zakharova, A.L. Zakharenko, Ji. Patel, D.M. Ayine-Tora, J. Reynisson, I.K. H. Leung, K.P. Volcho, N.F. Salakhutdinov, O.I. Lavrik
    The Development of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors. Combination of Monoterpene and Adamantine Moieties via Amide or Thioamide Bridges
    Applied Sciences, 2019, 9(13), 2767 doi:10.3390/app9132767, IF=2.217
  24. M.V. Kruchinina, A.A. Gromov, M.V. Shashkov, A.S. Sokolova, V.N. Kruchinin
    Peculiarities of fatty acid profile of erythrocyte membranes in patients with resistant arterial hypertension: possible contribution to pathogenesis of the disease
    JOURNAL OF HYPERTENSION, 2019, V. 37 , Pp E108-E108, Sup. 1 (29th European Meeting of Hypertension and Cardiovascular Protection of the European-Society-of-Hypertension (ESH), Milan, ITALY, JUN 21-24, 2019) doi:10.1097/01.hjh.0000571388.53224.97
  25. M.V. Kruchinina, A.A. Gromov, Ya.I. Prudnikova, M.V. Shashkov, A.S. Sokolova, V.N. Kruchinin, I.N. Yakovina, N.A. Bannova
    Perturbation of fatty acids of erythrocyte membranes and blood serum in patients with colorectal cancer: new opportunities for diagnostics
    Annals of Oncology. 2019. Т. 30. № S4. С. 109. Аннотация к встрече: P - 003 doi:10.1093/annonc/mdz155, IF=14.196
  26. Complexes of Zn(II) and Сu(II) with the Amino Derivatives of Deoxycholic Acid: Syntheses, Structures, and Properties/ T. E. Kokina, O. V. Salomatina, I. I. Popadyuk, L. A. Glinskaya, I. V. Korol'kov, L. A. Sheludyakova, M. I. Rakhmanova, N. F. Salakhutdinov// Russian Journal of Coordination Chemistry, July 2019, V. 45, N 7, pp 505-511 doi:10.1134/S1070328419070030, IF=0.636
  27. A.Yu.Sidorenko, A.V.Kravtsova, A.Aho, I.Heinmaa, J.Warna, H.Pazniak, K.P.Volcho, N.F.Salakhutdinov, D.Yu.Murzin, V.E.Agabekov
    Highly selective Prins reaction over acid-modified halloysite nanotubes for synthesis of isopulegol-derived 2H-chromene compounds
    Journal of Catalysis, 2019, V. 374, Pp 360-377 doi:10.1016/j.jcat.2019.05.009, IF=7.723
  28. T.M. Khomenko, D.V. Korchagina, D.S. Baev, P.M. Vassiliev, K.P. Volcho, N.F. Salakhutdinov
    Antimicrobial Activity of Substituted Benzopentathiepin-6-amines
    Journal of Antibiotics, 2019, V. 72, pp 590-599 doi:10.1038/s41429-019-0191-y, IF=2.446
  29. P. Maki-Arvela, N. Shcherban, Ch. Lozachmeur, K. Eranen, A. Aho, A. Smeds, N. Kumar, J. Peltonen, M. Peurla, V. Russo, K.P. Volcho, D.Yu. Murzin
    Aldol Condensation of Cyclopentanone with Valeraldehyde Over Metal Oxides
    Catalysis Letters, 2019, V. 149, N 5, pp 1383-1395 doi:10.1007/s10562-019-02701-1, IF=2.372
  30. Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones/ I. V. Il'ina, D. V. Korchagina, E. A. Morozova, T. G. Tolstikova, K. P. Volcho, N. F. Salakhutdinov// Russian Chemical Bulletin, 2019, V. 68, N 5, pp 1061-1066 doi:10.1007/s11172-019-2520-5, IF=1.014
  31. Synthesis, hypolipidemic and antifungal activity of tetrahydroberberrubine sulfonates/ I. V. Nechepurenko, E. D. Shirokova, M. V. Khvostov, T. S. Frolova, O. I. Sinitsyna, A. M. Maksimov, R. A. Bredikhin, N. I. Komarova, D. S. Fadeev, O. A. Luzina, T. G. Tolstikova, N. F. Salakhutdinova// Russian Chemical Bulletin, 2019, V. 68, N 5, pp 1052-1060 doi:10.1007/s11172-019-2519-y, IF=1.014
  32. Synthesis of (1S)-(+)-camphor-10-sulfonic acid derivatives and investigations in vitro and in silico of their antiviral activity as the inhibitors of fi lovirus infections/ A. S. Sokolova, D. V. Baranova, O. I. Yarovaya, D. S. Baev, O. A. Polezhaeva, A. V. Zybkina, D. N. Shcherbakov, T. G. Tolstikova, N. F. Salakhutdinov// Russian Chemical Bulletin, 2019, V 68, N 5, pp 1041-1046 doi:10.1007/s11172-019-2517-0, IF=1.014
  33. E.Mozhaitsev,E.Suslov,Yu. Demidova,D. Korchagina,K.Volcho,A. Zakharenko,I. Vasi'eva,M.Kupryushkin,A. Chepanova,D. M. Ayine-Tora,J.Reynisson,N. Salakhutdinov,O. Lavrik
    The Development of Tyrosyl-DNA Phosphodyesterase 1 (TDP1) Inhibitors Based on the Amines Combining Aromatic/Heteroaromatic and Monoterpenoid Moieties
    Letters in Drug Design & Discovery, 2019, V. 6, N 5, Pp 597-605 doi:10.2174/1570180816666181220121042, IF=0.953
  34. E.S. Mozhaitsev, A.L. Zakharenko, E.V. Suslov, D.V. Korchagina, O.D. Zakharova, I.A. Vasil’eva, A.A. Chepanova, E. Black, J. Patel, R. Chand, J. Reynisson, I.K. H. Leung, K.P. Volcho, N.F. Salakhutdinov, O.I. Lavrik
    Novel Inhibitors of DNA Repair Enzyme TDP1 Combining Monoterpenoid and Adamantane Fragments
    Anti-Cancer Agents in Medicinal Chemistry, 2019, V. 19 , N 4 , Pp 463-472 doi:10.2174/1871520619666181207094243, IF=2.18
  35. N.S. Li-Zhulanov, I.V. Il’ina, A. Chicca, P. Schenker, O.S. Patrusheva, E.V. Nazimova, D.V. Korchagina, M. Krasavin, K.P. Volcho, N.F. Salakhutdinov
    Effect of chiral polyhydrochromenes on cannabinoid system
    Medicinal Chemistry Research, 2019, V. 28, N 4, pp 450-464 doi:10.1007/s00044-019-02294-9, IF=1.72
  36. Yu.N. Antonenko, L.S. Khailova, T.I. Rokitskaya, E.S. Nosikova, P.A. Nazarov, O.A. Luzina, N.F. Salakhutdinov, E.A. Kotova
    Mechanism of action of an old antibiotic revisited: Role of calcium ions in protonophoric activity of usnic acid
    Biochimica et Biophysica Acta (BBA) - Bioenergetics, V. 1860, N 4, 1 April 2019, Pp 310-316 doi:10.1016/j.bbabio.2019.01.005, IF=4.441
  37. Ju.A. Sidorova, K.P. Volcho, N.F. Salakhutdinov
    Neuroregeneration in Parkinson’s Disease: From Proteins to Small Molecules
    Current Neuropharmacology, 2019,V. 17 , N 3 , Pp. 268 - 287 doi:10.2174/1570159X16666180905094123, IF=4.568
  38. Synthesis of diazaadamantanes from 1,5-dimethylbispidinone and some natural ketones/ Suslov E.V.1, Ponomarev K. Yu.1, Korchagina D.V.1, Volcho K.P.1,2, Salakhutdinov N.F.// Russian Chemical Bulletin, 2019, V. 68, N 3, pp 601-605 doi:10.1007/s11172-019-2461-z, IF=1.014
  39. A.Kulikov,N.Sinyakova,E.Kulikova,N.Evglevsky,I.Kolotygin,K.Volcho,N.Salakhutdinov,V.Kulikov,A.Romaschenko,M.Moshkin
    Effects of acute and chronic treatment of STEP inhibitor, TC-2153, on the nervous system and behaviour of zebrafish (Danio rerio)
    European Neuropsychopharmacology, V. 29, Supplement 1, 2019, Pp S198-S199, P.216 doi:10.1016/j.euroneuro.2018.11.330, IF=4.468
  40. A.G. Ogienko, A.V. Markov, A.V. Sen'kova, E.B. Logashenko, O.V. Salomatina, S.A. Myz, A.A. Ogienko, A.A. Nefedov, E.A. Losev, T.N. Drebushchak, N.F. Salakhutdinov, V.V. Boldyrev, V.V. Vlasov, M.A. Zenkova, E.V. Boldyreva
    Increasing bioavailability of very poorly water-soluble compounds. A case study of an anti-tumor drug, soloxolon methyl
    Journal of Drug Delivery Science and Technology, 2019, V. 49, Pages 35-42 doi:10.1016/j.jddst.2018.10.025, IF=2.606
  41. N. Dyrkheeva, O. Luzina, A. Filimonov, O. Zakharova, E. Ilina, A. Zakharenko, M. Kuprushkin, D. Nilov, I. Gushchina, V. Svedas, N. Salakhutdinov, O. Lavrik
    Inhibitory Effect of New Semisynthetic Usnic Acid Derivatives on Human Tyrosyl-DNA Phosphodiesterase 1
    Planta Medica, 2019, V. 85, N 2, Pp 103-111 doi:10.1055/a-0681-7069, IF=2.746
  42. A.L. Zakharenko, O.A. Luzina, D.N. Sokolov, V.I. Kaledin, V.P. Nikolin, N.A. Popova, J. Patel, O.D. Zakharova, A.A. Chepanova, A. Zafar, J. Reynisson, E. Leung, I.K-H. Leung, K.P. Volcho, N.F. Salakhutdinov, O.I. Lavrik
    Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models
    European Journal of Medicinal Chemistry, 2019, V. 161, Pages 581-593 doi:10.1016/j.ejmech.2018.10.055, IF=4.833

2018
  1. E.A. Kulikova, N.V. Khotskin, N.B. Illarionova, I.E. Sorokin, E.Y. Bazhenova, E.M. Kondaurova, K.P. Volcho, T.M. Khomenko, N.F. Salakhutdinov, E. Ponimaskin, V.S. Naumenko, A.V. Kulikov
    Inhibitor of striatal-enriched protein tyrosine phosphatase, 8-(trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine hydrochloride (TC-2153), produces antidepressant-like effect and decreases functional activity and protein level of 5-HT2A receptor in the brain
    Neuroscience, 2018, V. 394, Pp 220-231 doi:10.1016/j.neuroscience.2018.10.031, IF=3.381
  2. K.S. Kovaleva, F.I. Zubkov, N.I. Bormotov, R.A. Novikov, P.V. Dorovatovskii, V.N. Khrustalev, Yu.V. Gatilov, V.V. Zarubaev, O.I. Yarovaya, L.N. Shishkin, N.F. Salakhutdinov
    Synthesis of D-(+)-camphor-based N-acylhydrazones and their antiviral activity
    Med. Chem. Commun., 2018, V. 9, N 12, Pp 2072-2082 doi:10.1039/C8MD00442K, IF=2.342
  3. A.D. Rogachev, O.I. Yarovaya, A.V. Fatianova, V.A. Lavrinenko, E.V. Amosov, V.V. Zarubaev, A.G. Pokrovsky, N.F. Salakhutdinov
    Untargeted search and identification of metabolites of antiviral agent camphecene in rat urine by liquid chromatography and mass spectrometry and studying their distribution in organs following peroral administration of the compound
    Journal of Pharmaceutical and Biomedical Analysis, 2018, V. 161, Pp 383-392 doi:10.1016/j.jpba.2018.09.003, IF=2.831
  4. V.V. Zarubaev, E.A. Pushkina, S.S. Borisevich, A.V. Galochkina, A.V. Garshinina, A.A. Shtro, A.A. Egorova, A.S. Sokolova, S.L. Khursan, O.I. Yarovaya, N.F. Salakhutdinov
    Selection of influenza virus resistant to the novel camphor-based antiviral camphecene results in loss of pathogenicity
    Virology, V. 524, November 2018, Pp 69-77 doi:10.1016/j.virol.2018.08.011, IF=3.374
  5. A.Yu. Sidorenko, I.V. Il'ina, A.V. Kravtsova, A. Aho, O.V. Ardashov, N.S. Li-Zhulanov, K.P. Volcho, N.F. Salakhutdinov, D.Yu. Murzin, V.E. Agabekov
    Preparation of chiral isobenzofurans from 3-carene in the presence of modified clays
    Molecular Catalysis, 2018, V. 459, Pp 38-45 doi:10.1016/j.mcat.2018.07.025
  6. Antimetastatic Activity of Combined Topotecan and Tyrosyl-DNA Phosphodiesterase-1 Inhibitor on Modeled Lewis Lung Carcinoma/ E. V. Koldysheva, A. P. Men'shchikova, E. L. Lushnikova, N. A. Popova, V. I. Kaledin, V. P. Nikolin, A. L. Zakharenko, O. A. Luzina, N. F. Salakhutdinov, O. I. Lavrik// Bulletin of Experimental Biology and Medicine, March 2019, V. 166, N 5, pp 661-666 doi:10.1007/s10517-019-04413-3, IF=0.546
  7. V.I. Anikeev, V.P. Sivcev, K.R. Valeev, K.P. Volcho, V.A. Sadykov, N.F. Salakhutdinov
    Highly selective reduction of nitroarenes by sc-isopropanol in the presence of zirconia in a flow reactor
    The Journal of Supercritical Fluids, V. 140, October 2018, Pp 233-237 doi:10.1016/j.supflu.2018.06.021, IF=3.122
  8. Molecular and Supramolecular Structure of 8-(Trifluoromethyl)Benzo[f][1,2,3,4,5] Pentathiepin-6-Amine - A Representative of Condensed Arene Pentathiepines/ T. V. Rybalova, A. D. Rogachev, T. M. Khomenko, K. P. Volcho, N. F. Salakhutdinov// Journal of Structural Chemistry, 2018, V. 59, N 7, pp 1753-1758 doi:10.1134/S0022476618070326, IF=0.521
  9. A.S. Sokolova, O.I. Yarovaya, N.I. Bormotov, L.N. Shishkina, N.F. Salakhutdinov
    Synthesis and antiviral activity of camphor-based 1,3-thiazolidin-4-one and thiazole derivatives as Orthopoxvirus-reproduction inhibitors
    Med. Chem. Commun,, 2018, V. 9, N 10, Pp 1746-1753 doi:10.1039/C8MD00347E, IF=2.342
  10. N.S. Li-Zhulanov, A.L. Zakharenko, A.A. Chepanova, Ji. Patel, A. Zafar, K.P. Volcho, N.F. Salakhutdinov, J. Reynisson, I.K. H. Leung, O.I. Lavrik
    A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2H-chromen-4-ol Scaffold
    Molecules 2018, 23(10), 2468; doi:10.3390/molecules23102468, IF=3.098
  11. A. Sidorenko, A. Kravtsova, A. Aho, I. Heinmaa, V. Agabekov, K. Volcho, N. Salakhutdinov, D. Murzin
    Acid-modified Halloysite Nanotubes as a Stereoselective Catalyst for Synthesis of 2H-Chromene Derivatives by the Reaction of Isopulegol with Aldehydes
    ChemCatChem, 2018, V. 10, N 18, Pp 3950-3954 doi:10.1002/cctc.201800974, IF=4.674
  12. А.В. Ластовка, Е.Ю. Яковлева, В.Ф. Коллегов, В.П. Фадеева, Н.Ф. Салахутдинов
    Определение остаточных органических растворителей методом газовой хроматографии в субстанции (2R,4R,4AR,7R, 8AR)-4,7-диметил-2-(тиофен-2-ил)октагидро-2H-хромен-4-ол, обладающей анальгетической активностью
    Заводская лаборатория. Диагностика материалов. 2018. Т. 84. № 9. С. 13-20. doi:10.26896/1028-6861-2018-84-9-13-20
  13. A.S. Sokolova, O.I. Yarovaya, N.I. Bormotov, L.N. Shishkina, N.F. Salakhutdinov
    Discovery of a new class of inhibitors of Vaccinia virus based on (-)-borneol from Abies sibirica and (+)-camphor
    Chemistry & Biodiversity, 2018, V. 15, N 9, e1800153 doi:10.1002/cbdv.201800153, IF=1.617
  14. O. Zakharov, O. Luzina, A. Zakharenko, D. Sokolov, A. Filimonov, N. Dyrkheeva, A. Chepanova, E. Ilina, A. Ilyina, K. Klabenkova, B. Chelobanov, D. Stetsenko, A. Zafar, Ch. Eurtivong, J. Reynisson, K. Volcho, N. Salakhutdinov, O. Lavrik
    Synthesis and evaluation of aryliden- and hetarylidenfuranone derivatives of usnic acid as highly potent Tdp1 inhibitors
    Bioorganic & Medicinal Chemistry, 2018, V. 26, N 15, Pp 4470-4480 doi:10.1016/j.bmc.2018.07.039, IF=2.881
  15. S.O. Kuranov, I.P. Tsypysheva, M.V. Khvostov, L.F. Zainullina, S.S. Borisevich, Yu.V. Vakhitova, O.A. Luzina, N.F. Salakhutdinov
    Synthesis and evaluation of camphor and cytisine-based cyanopyrrolidines as DPP-IV inhibitors for the treatment of type 2 diabetes mellitus
    Bioorganic & Medicinal Chemistry, 2018, V. 26, N 15, Pp 4402-4409 doi:10.1016/j.bmc.2018.07.018, IF=2.881
  16. Synthesis of oxygen-containing heterocyclic compounds based on monoterpenoids/ O S Patrusheva, K P Volcho, N F Salakhutdinov// RUSS CHEM REV, 2018, V. 87, N 8, Pp 771-796 doi:10.1070/RCR4810, IF=3.991
  17. A.Yu. Sidorenko, A.V. Kravtsova, J. Warna, A. Aho, I. Heinmaa, I.V. Il'ina, O.V. Ardashov, K.P. Volcho, N.F. Salakhutdinov, D.Yu. Murzin, V.E. Agabekov
    Preparation of octahydro-2H-chromen-4-ol with analgesic activity from isopulegol and thiophene-2-carbaldehyde in the presence of acid-modified clays
    Molecular Catalysis, 2018, V. 453, Pp. 139-148 doi:10.1016/j.mcat.2018.05.007
  18. A.L. Zakharenko, E.S. Mozhaitsev, E.V. Suslov, D.V. Korchagina, K.P. Volcho, N.F. Salakhutdinov, O.I. Lavrik
    Synthesis and Inhibitory Properties of Imines Containing Monoterpenoid and Adamantane Fragments Against DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1 (Tdp1)
    Chemistry of Natural Compounds, 2018, V. 54, N 4, pp 672-676 doi:10.1007/s10600-018-2443-7, IF=0.449
  19. I.V. Ilyina, V.V. Zarubaev, I.N. Lavrentieva, A.A. Shtro, I.L. Esaulkova, D.V. Korchagina, S.S. Borisevich, K.P. Volcho, N.F. Salakhutdinov
    Highly potent activity of isopulegol-derived substituted octahydro-2H-chromen-4-ols against influenza A and B viruses
    Bioorganic & Medicinal Chemistry Letters, 2018, V. 28, N 11, Pp 2061-2067 doi:10.1016/j.bmcl.2018.04.057, IF=2.371
  20. Study of the level of fatty acids in erythrocyte membranes and serum of patients with colorectal cancer in Novosibirsk/ M.V. Kruchinina, V.N. Kruchinin, Ya.I. Prudnikova, A.A. Gromov, M.V. Shashkov, A.S. Sokolova// doi:10.17650/2313-805X-2018-5-2-50-61
  21. O.A. Luzina, N.F. Salakhutdinov
    Usnic acid and its derivatives for pharmaceutical use: a patent review (2000–2017)
    Expert Opinion on Therapeutic Patents, 2018, V.28, N 6, Pp 477-491 doi:10.1080/13543776.2018.1472239, IF=2.867
  22. А.С. Донченко, В.В. Фоменко, В.Г. Васильев, В.Н. Афонюшкин, Н.А. Донченко, Ю.Н. Козлова, В.Ю. Коптев
    Изучение антагонистической активности бактерий, подавляющей синтез феназинов Pseudomonas aereginosa
    Сибирский вестник сельскохозяйственной науки, 2018. Т. 48. №.5. С. 23-29. doi: 10.26898/0370-8799-2018-5-3 doi:10.26898/0370-8799-2018-5-3
  23. Yu.S. Demidova, E.V. Suslov, I.L. Simakova, E.S. Mozhajcev, D.V. Korchagina, K.P. Volcho, N.F. Salakhutdinov, A. Simakov, D.Yu. Murzin
    One-pot monoterpene alcohol amination over Au/ZrO2 catalyst: Effect of the substrate structure
    Journal of Catalysis, 2018, V. 360, Pages 127-134 doi:10.1016/j.jcat.2018.01.020, IF=6.759
  24. V.Yu. Krukov, O.G. Tomilova, O.A. Luzina, O.N. Yaroslavtseva, Yu.B. Akhanaev, M.V. Tyurin, B.A. Duisembekov, N.F. Salakhutdinov, V.V. Glupov
    Effects of fluorine-containing usnic acid and fungus Beauveria bassiana on the survival and immune-physiological reactions of Colorado potato beetle larvae
    Pest Management Science, 2018, V. 74, N 3, Pp 598-606 doi:10.1002/ps.4741, IF=3.249
  25. Antiulcer and anti-inflammatory activity of the campholenic aldehyde-derived thiazolidinone/ BORISOVA Marina Sergeevna, SOKOLOV Dmitriy Nikolaevich, ZHUKOVA Natalya Anatolevna, TOLSTIKOVA Tatyana Genrikhovna, SALAKHUTDINOV Nariman Faridovich// doi:10.15372/SSMJ20180201
  26. O.V. Salomatina, I.I. Popadyuk, A.L. Zakharenko, O.D. Zakharova, D.S. Fadeev, N.I. Komarova, J. Reynisson, H.J. Arabshahi, R. Chand, K.P. Volcho, N.F. Salakhutdinov, O.I. Lavrik
    Novel semisynthetic derivatives of bile acids as effective tyrosyl-DNA phosphodiesterase 1 inhibitors
    Molecules, 2018, V. 23, N 3, art. number 679 doi:10.3390/molecules23030679, IF=3.098
  27. Antiulcerogenic activity of borneol derivatives/ M. S. Borisova, O. I. Yarovaya, M. D. Semenova, T. G. Tolstikova, N. F. Salakhutdinov// Russian Chemical Bulletin, 2018, V. 67, N 3, Pp 558-561 doi:10.1007/s11172-018-2110-y, IF=0.781
  28. D.S. Sergeevichev, A.A. Krasilnikova, A.G. Strelnikov, V.V. Fomenko, N.F. Salakhutdinov, A.B. Romanov, A.M. Karaskov, E.A. Pokushalov, J.S. Steinberg
    Globular chitosan prolongs the effective duration time and decreases the acute toxicity of botulinum neurotoxin after intramuscular injection in rats
    Toxicon, 2018, V. 143, Pp 90-95 doi:10.1016/j.toxicon.2018.01.013, IF=2.352
  29. K.Yu. Ponomarev, E.V. Suslov, A.L. Zakharenko, O.D. Zakharova, A.D. Rogachev, D.V. Korchagina, A. Zafar, J. Reynisson, A.A. Nefedov, K.P. Volcho, N.F. Salakhutdinov, O.I. Lavrik
    Aminoadamantanes Containing Monoterpene-derived Fragments as Potent Tyrosyl-DNA phosphodiesterase 1 Inhibitors
    Bioorganic Chemistry, V.76, February 2018, Pp. 392-399 doi:10.1016/j.bioorg.2017.12.005, IF=3.929
  30. A.A. Krasilnikova, D.S. Sergeevichev, V.V. Fomenko, A.A. Korobeynikov, M.B. Vasilyeva, A.S. Yunoshev, A.M. Karaskov, E.A. Pokushalov
    Globular chitosan treatment of bovine jugular veins: Evidence of anticalcification efficacy in the subcutaneous rat model
    Cardiovascular Pathology, V. 32, January-February 2018, Pp 1-7 doi:10.1016/j.carpath.2017.08.003, IF=2.496
  31. K.P. Volcho, S.S. Laev, G.M. Ashraf, G. Aliev, N.F. Salakhutdinov
    Application of monoterpenoids and their derivatives for treatment of neurodegenerative disorders.
    Curr Med Chem., 2018, V. 25, N 39, Pp 5327 - 5346 doi:10.2174/0929867324666170112101837, IF=3.469
  32. CHANGES OF LIPIDOM IN COLORECTAL CANCER/ Kruchinina M.V., Gromov A.A., Prudnikova Ia.I., Kruchinin V.N., Shashkov M.V., Sidelnikov V.N., Sokolova A.S., Salakhutdinov N.F.// doi:10.15372/ATER20180107
  33. D.N. Sokolov, O.A. Luzina, N.F. Salakhutdinov
    Synthesis of Sulfones and Sulfoxides Based on (+)-usnic Acid
    Chemistry of Natural Compounds, 2018, V. 54, N 1, pp 46-49 doi:10.1007/s10600-018-2256-8, IF=0.45

2017
  1. A. Kononova, A. Sokolova, S. Cheresiz, O. Yarovara, R. Nikitina, A. Chepurnov, A.G. Pokrovsky, N. Salakhutdonov
    N-Heterocyclic borneol derivatives as the inhibitors of Marburg virus glycoprotein-mediated VSIV pseudotype entry
    Med. Chem. Commun., 2017, V. 8, N 12, Pp 2233-2237 doi:10.1039/C7MD00424A, IF=2.608
  2. K.Yu. Ponomarev, E.A. Morozova, E.V. Suslov, D.V. Korchagina, T.G. Tolstikova, K.P. Volcho, N.F. Salakhutdinov
    Synthesis and Analgesic Activity of 5,7- and 6-Substituted Diazaadamantanes Containing Monoterpene Moieties
    Chemistry of Natural Compounds, 2017, V. 53, N 6, Pp 1131-1136 doi:10.1007/s10600-017-2216-8, IF=0.46
  3. O.S. Patrusheva, A.V. Pavlova, D.V. Korchagina, T.G. Tolstikova, K.P. Volcho, N.F. Salakhutdinov
    Synthesis and Analgesic Activity of 4,7-Dimethyl-3,4,4a,5,8,8a-Hexahydro-2-Chromen-4,8-Diols Containing Alkyl-Substituted Aromatic Moieties
    Chemistry of Natural Compounds, 2017, V. 53, N 6, Pp 1066-1071 doi:10.1007/s10600-017-2202-1, IF=0.46
  4. Development and Validation of a Method for Determination of a New Effective Inhibitor of Influenza Virus H1N1 in Blood Plasma/ A. S. Sokolova, O. I. Yarovaya, A. A. Nefedov, N. F. Salakhutdinov// Pharmaceutical Chemistry Journal, 2018, V. 51, N 12, pp 1102-1105 doi:10.1007/s11094-018-1748-y, IF=0.444
  5. A.V. Markov, A.V. Sen'kova, D. Warszycki, O.V. Salomatina, N.F. Salakhutdinov, M.A. Zenkova, E.B. Logashenko
    Soloxolone methyl inhibits influenza virus replication and reduces virus-induced lung inflammation
    Scientific Reports, 2017, V. 7, Номер статьи 13968 doi:10.1038/s41598-017-14029-0, IF=4.258
  6. I.I. Popadyuk, A.V. Markov, E.A. Morozova, V.O. Babich, O.V. Salomatina, E.B. Logashenko, M.A. Zenkova, T.G. Tolstikova, N.F. Salakhutdinov
    Synthesis and evaluation of antitumor, anti-inflammatory and analgesic activity of novel deoxycholic acid derivatives bearing aryl- or hetarylsulfanyl moieties at the C-3 position
    Steroids, 2017, V. 127, Pp 1-12 doi:10.1016/j.steroids.2017.08.016, IF=2.282
  7. M.V. Trushin, R.G. Khamidullina, O.V. Ardashov, K.P. Volcho, N.F. Salakhutdinov
    The action of monoterpenoids with promising antiparkinsonian activity on fertility of Drosophila melanogaster
    Marmara Pharmaceutical Journal, 2017, V. 21, N 4, 2017, Pp 987-991 doi:10.12991/mpj.2017.29
  8. E.A. Kulikova, N.B. Illarionova, K.P. Volcho, T.A. Khomenko, N.F. Salakhutdinov, N.V. Khotskin, E.Y. Bazhenova, A.V. Kulikov
    The effect of TC-2153, an inhibitor of striatal-enriched protein tyrosine phosphatase, on the 5-HT2A receptors
    European Neuropsychopharmacology, 2017, V. 27, pp S654-S654, S4 (30th Congress of the European-College-of-Neuropsychopharmacology (ECNP), Paris, France, Sep 02-05, 2017) doi:10.1016/S0924-977X(17)31224-5, IF=4.238
  9. А. В. Ластовка, В. П. Фадеева, И. В. Ильина, С. Ю. Курбакова, К. П. Волчо, Н. Ф. Салахутдинов
    Исследование физико-химических свойств и разработка методики определения (2R,4R,4aR,7R,8aR)-4,7-диметил-2- (тиофен-2-ил)октагидро-2H-хромен-4-ола, обладающего высокой анальгетической активностью
    Заводская лаборатория, 2017, Т. 83, № 10, С. 11-17 doi:10.26896/1028-6861-2017-83-11-17
  10. E. Suslov, V.V. Zarubaev, A.V. Slita, K. Ponomarev, D. Korchagina, D.M. Ayine-Tora, J. Reynisson, K. Volcho, N. Salakhutdinov
    Anti-Influenza Activity of Diazaadamantanes Combined with Monoterpene Moieties
    Bioorganic & Medicinal Chemistry Letters, 2017, V. 27, N 19, Pp 4531-4535 doi:10.1016/j.bmcl.2017.08.062, IF=2.453
  11. A. Romanov, A. Strelnikov, D. Sergeevichev, N. Salakhutdinov, V. Fomenko, V. Shabanov, D. Losik, I. Mikheenko, A. Karaskov, E. Pokushalov
    The influence of the new pharmaceutical composition containing botulinum toxin on different pharmacological models of heart rhythm disorders
    European Heart Journal. 38 (Supplement). 2017. P1711 (ESC Congress 2017, 26-30 August, Barcelona, Spain) doi:10.1093/eurheartj/ehx502.P1711, IF=0.896
  12. М.В. Кручинина, М.В. Паруликова, С.А. Курилович, А.А. Громов, В.М. Генералов, В.А. Рихтер, Д.В. Семенов, С.В. Морозов, А.С. Соколова, Н.Ф. Салахутдинов, М.В. Шашков, В.Н. Сидельников, В.Н. Кручинин
    Ассоциации функциональных параметров эритроцитов со структурой их мембран у мужчин г. новосибирска с атерогенными дислипидемиями и алкогольным поражением печени
    Атеросклероз. 2017. Т. 13. № 3. С. 5-13.
  13. I.I. Popadyuk, A.V. Markov, V.O. Babich, O.V. Salomatina, E.B. Logashenko, M.A. Zenkova, N.F. Salakhutdinov
    Novel derivatives of deoxycholic acid bearing aliphatic or cyclic diamine moieties at the C-3 position: synthesis and evaluation of anti-proliferative activity
    Bioorganic & Medicinal Chemistry Letters, 2017, V. 27, N 16, Pp 3755-3759 doi:10.1016/j.bmcl.2017.06.072, IF=2.453
  14. K. Ponomarev, E. Morozova, A. Pavlova, E. Suslov, D. Korchagina, A. Nefedov, T. Tolstikova, K. Volcho, N. Salakhutdinov
    Synthesis and Analgesic Activity of Amines Combining Diazaadamantane and Monoterpene Fragments
    Medicinal Chemistry, 2017, V. 13 , N 8, Pp 773 - 779 doi:10.2174/1573406413666170525124316, IF=2.331
  15. Catalytic epoxidation of β-pinene with aqueous hydrogen peroxide/ V. V. Fomenko, O. V. Bakhvalov, V. F. Kollegov, N. F. Salakhutdinov// Russian Journal of General Chemistry, 2017, V.87, N 8, pp 1675-1679 doi:10.1134/S1070363217080059, IF=0.552
  16. E.A. Kulikova, K.P. Volcho, N.F. Salakhutdinov, A.V. Kulikov
    Benzopentathiepine Derivative, 8-(Trifluoromethyl)-1,2,3,4,5-Benzopentathiepin-6-Amine Hydrochloride (TC-2153), as a Promising Anti-depressant of New Generation
    Letters in Drug Design & Discovery, 2017, V. 14, N 8, Pp 974-984 doi:10.2174/1570180814666161121112417, IF=1.169
  17. N.F. Salakhutdinov, K.P. Volcho, O.I. Yarovaya
    Monoterpenes as a renewable source of biologically active compounds
    Pure and Applied Chemistry, 2017, V.89, N 8, pp 1105-1118 doi:10.1515/pac-2017-0109, IF=2.625
  18. I. Il'ina, A. Pavlova, D. Korchagina, O. Ardashov, T. Tolstikova, K. Volcho, N. Salakhutdinov
    Synthesis and analgesic activity of monoterpenoid-derived alkyl-substituted chiral hexahydro-2H-chromenes
    Medicinal Chemistry Research, 2017, V. 26, N 7, pp 1415-1426 doi:10.1007/s00044-017-1847-4, IF=1.276
  19. T.M. Khomenko, V.V. Zarubaev, I.R. Orshanskaya, R.A. Kadyrova, V.A. Sannikova, D.V. Korchagina, K.P. Volcho, N.F. Salakhutdinov
    Anti-influenza activity of monoterpene-containing substituted coumarins
    Bioorganic & Medicinal Chemistry Letters, 2017, V. 27, N 13, Pp 2920-2925 doi:10.1016/j.bmcl.2017.04.091, IF=2.453
  20. O.I. Artyushin, E.V. Sharova, N.M. Vinogradova, G.K. Genkina, A.A. Moiseeva, Z.S. Klemenkova, I.R. Orshanskaya, A.A. Shtro, R.A. Kadyrova, V.V. Zarubaev, O.I. Yarovaya, N.F. Salakhutdinov, V.K. Brel
    Synthesis of Camphecene Derivatives using Click Chemistry Methodology and Study of their Antiviral Activity
    Bioorganic & Medicinal Chemistry Letters, 2017, V.27, N 10, Pp 2181-2184 doi:10.1016/j.bmcl.2017.03.051, IF=2.453
  21. Yu.S. Demidova, E.V. Suslov, I.L. Simakova, K.P. Volcho, E. Smolentseva, N.F. Salakhutdinov, A. Simakov, D.Yu. Murzin
    Promoting effect of alcohols and formic acid on Au-catalyzed one-pot myrtenol amination
    Molecular Catalysis, 2017, V. 433, Pp 414-419 (Formerly known as Journal of Molecular Catalysis A: Chemical) doi:10.1016/j.mcat.2017.02.040, IF=4.211
  22. A.S. Sokolova, O.I. Yarovaya, M.D. Semenova, A.A. Shtro, I.R. Orshanskaya, V.V. Zarubaev, N.F. Salakhutdinov
    Synthesis and in vitro study of novel borneol derivatives as potent inhibitors of the influenza A virus
    Med. Chem. Commun., 2017, 8(5), 960-963 doi:10.1039/C6MD00657D, IF=2.608
  23. S.S. Laev, N.F. Salakhutdinov, O.I. Lavrik
    Inhibitors of nuclease and redox activity of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1)
    Bioorganic & Medicinal Chemistry, 2017, V. 25, N 9, Pp 2531-2544 doi:10.1016/j.bmc.2017.01.028, IF=2.93
  24. Modern approaches to modification of bile acids for the synthesis of compounds possessing valuable physicochemical and biological properties/ I.I. Popadyuk, O.V. Salomatina, N. F. Salakhutdinov// Russian Chemical Reviews, 2017, V. 86, N 5, Pp 388-443 doi:10.1070/RCR4683, IF=4.58
  25. A. Pavlova, O. Patrusheva, I. Il'ina, K. Volcho, T. Tolstikova, N. Salakhutdinov
    The Decisive Role of Mutual Arrangement of Hydroxy and Methoxy Groups in (3(4)-hydroxy-4(3)-methoxyphenyl)-4,7-dimethyl-3,4,4a,5,8,8ahexahydro- 2H-chromene-4,8-diols in their Biological Activity
    Letters in Drug Design & Discovery, 2017, V. 14, N 5, pp. 508-514 doi:10.2174/1570180813666161102142642, IF=1.169
  26. K.S. Kovaleva, O.I. Yarovaya, D.S. Fadeev, N.F. Salakhutdinov
    One-pot synthesis of 1,5,3-oxathiazepanes via the three-component condensation of primary amines, formaldehyde and 2-mercaptoethanol
    Tetrahedron Letters, 2017, V. 58, N 19, Pp 1868-1870 doi:10.1016/j.tetlet.2017.03.090, IF=2.193
  27. М.В. Кручинина, Я.И. Прудникова, В.Н. Кручинин, В.А. Володин, М.В. Шашков, А.С. Соколова
    Возможности неинвазивной диагностики колоректального рака методами хроматографии и RAMAN-спектроскопии
    Гастроэнтерология Санкт-Петербурга, 2017. № 1. С. 86-86
  28. A.S. Sokolova, O.I. Yarovaya, A.A. Shtro, M.S. Borisova, E.A. Morozova, T.G. Tolstikova, V.V. Zarubaev, N.F. Salakhutdinov
    Synthesis and biological activity of heterocyclic borneol derivatives
    Chemistry of Heterocyclic Compounds, 2017, V. 53, N 3, pp 371-377 doi:10.1007/s10593-017-2063-3, IF=0.893
  29. K.S. Kovaleva, O.I. Yarovaya, A.V. Shernyukov, V.V. Zarubaev, A.A. Shtro, Ya.R. Orshanskaya, N.F. Salakhutdinov
    Synthesis of new heterocyclic dehydroabietylamine derivatives and their biological activity
    Chemistry of Heterocyclic Compounds, 2017, V. 53, N 3, pp 364-370 doi:10.1007/s10593-017-2058-0, IF=0.893
  30. E.V. Nazimova, A.A. Shtro, V.B. Anikin, O.S. Patrusheva, I.V. Il'ina, D.V. Korchagina, V.V. Zarubaev, K.P. Volcho, N.F. Salakhutdinov
    Influenza Antiviral Activity of Br-Containing [2R,4R(S),4aR,7R,8aR]-4,7-Dimethyl-2-(Thiophen-2-YL)Octahydro-2H-Chromen-4-Ols Prepared from (–)-Isopulegol
    Chemistry of Natural Compounds, 2017, V. 53, N 2, pp 260-264 doi:10.1007/s10600-017-1966-7, IF=0.46
  31. A.S. Sokolova, О.I. Yarovaya, D.S. Baev, А.V. Shernyukov, A.A. Shtro, V.V. Zarubaev, N.F. Salakhutdinov
    Aliphatic and alicyclic camphor imines as effective inhibitors of influenza virus H1N1
    European Journal of Medicinal Chemistry, 2017, V. 127, Pp 661-670 doi:10.1016/j.ejmech.2016.10.035, IF=4.519
  32. A.S. Kuzmich, T.M. Khomenko, S.N. Fedorov, T.N. Makarieva, L.K. Shubina, N.I. Komarova, D.V. Korchagina, T.V. Rybalova, K.P. Volcho, N.F. Salakhutdinov
    Cytotoxic and cancer preventive activity of benzotrithioles and benzotrithiole oxides, synthetic analogues of varacins
    Medicinal Chemistry Research, 2017, V. 26, N 2, pp 397-404 doi:10.1007/s00044-016-1759-8, IF=1.276
  33. I.L. Simakova, Yu.S. Demidova, M. Estrada, S. Beloshapkin, E.V. Suslov, K.P. Volcho, N.F. Salakhutdinov, D.Yu. Murzin, A. Simakov
    Gold catalyzed one-pot myrtenol amination: Effect of catalyst redox activationOriginal Research Article
    Сatalysis Today, V. 279, Part 1, 1 January 2017, Pages 63-70 doi:10.1016/j.cattod.2016.01.044, IF=4.636
  34. M. Stekrova, P. Maki-Arvela, E. Leino, K.M. Valkaj, K. Eranen, A. Aho, A. Smeds, N. Kumar, K.P. Volcho, N.F. Salakhutdinov, D.Yu. Murzin
    Two-step synthesis of monoterpenoid dioxinols exhibiting analgesic activity from isopulegol and benzaldehyde over heterogeneous catalysts
    Catalysis Today, Catalysis Today, V. 279, Part 1, 1 January 2017, Pp 56-62 doi:10.1016/j.cattod.2016.03.046, IF=4.636
  35. А.Г. Стрельников, Н.Ф. Салахутдинов
    Ботокс для сердца
    Наука из первых рук. 2017. Т. 73. № 1. С. 66-71.
  36. Usnic acid derivatives are effective inhibitors of tyrosyl-DNA phosphodiesterase 1/ A.L. Zakharenko, O.A. Luzina, D.N. Sokolov, O.D. Zakharova, M.E. Rakhmanova, A.A. Chepanova, N.S. Dyrkheeva, O.I. Lavrik, N.F. Salakhutdinov// Russian Journal of Bioorganic Chemistry, January 2017, Volume 43, Issue 1, pp 84-90 doi:10.1134/S1068162017010125, IF=0.689
  37. Yu.S. Demidova, E.V. Suslov, I.L. Simakova , E.S. Mozhajcev, D.V. Korchagina, K.P. Volcho, N.F. Salakhutdinov, A. Simakov, D.Yu. Murzin
    Selectivity control in one-pot myrtenol amination over Au/ZrO2 by molecular hydrogen addition
    Journal of Molecular Catalysis A: Chemical, V. 426, Part A, January 2017, Pages 60–67 doi:10.1016/j.molcata.2016.10.034, IF=3.957
  38. E. Valdman, I. Kapitsa, Е. Ivanova, T. Voronina, O. Ardashov, K. Volcho, V. Khazanov, N. Salakhutdinov
    Evolution of anti-parkinsonian activity of monoterpenoid (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in various in vivo models
    European Journal of Pharmacology, 2017, V. 815, Pp 351-363 doi:10.1016/j.ejphar.2017.09.022, IF=2.895

2016
  1. A.A. Shtro, V.V. Zarubaev, O.A. Luzina, D.N. Sokolov, N.F. Salakhutdinov
    Derivatives of usnic acid inhibit broad range of influenza viruses and protect mice from lethal influenza infection
    Antivir Chem Chemotherapy, V.24, N 3-4, August 2015, pp. 92-98, Published March 27, 2016 doi:10.1177/2040206616636992
  2. D. Sergeevichev, V. Fomenko, A. Dokuchaeva, E. Chepeleva, A. Korobeynikov, N. Salakhutdinov, E. Pokushalov, A. Karaskov
    Preventing Calcification and Improving Biomechanical Issues of Vein Tissues Using Chitosan
    Tissue Engineering: Part A. 2016. Vol.22, Suppl.1, S.141 DOI: 10.1089/ ten.tea.2016.5000.abstracts (conference TERMIS - Americas Conference and Exhibition, San Diego, CA, DEC 11-14, 2016), IF=3.891
  3. Sergeevichev, V. Fomenko, A. Strelnikov, A. Dokuchaeva, A. Korobeynikov, E. Chepeleva, N. Salakhutdinov, E. Pokushalov, A. Karaskov
    Denervation Properties of Botullinum Neurotoxin Type A in Complex with Chitozan
    Tissue Engineering: Part A. 2016. Vol.22, Suppl.1, S.46 DOI: 10.1089/ ten.tea.2016.5000.abstracts (conference TERMIS - Americas Conference and Exhibition, San Diego, CA, DEC 11-14, 2016), IF=3.891
  4. Chemical approach to the design of effective antidiabetic agents/ A D Rogachev, ab S O Kuranov, a N F Salakhutdinov// RUSS CHEM REV, 2016, V. 85, N 12, Pp 1313-1337 doi:10.1070/RCR4624, IF=3.687
  5. A.D. Rogachev, O.I. Yarovaya, S.V. Ankov, M.V. Khvostov, T.G. Tolstikova, A.G. Pokrovsky, N.F. Salakhutdinov
    Development and validation of ultrafast LC–MS/MS method for quantification of anti-influenza agent camphecene in whole rat blood using dried blood spots and its application to pharmacokinetic studies
    Journal of Chromatography B, Volumes 1036-1037, 15 November 2016, Pages 136-141 doi:10.1016/j.jchromb.2016.10.009, IF=2.687
  6. A.Zakharenko, O. Luzina, O.Koval, D. Nilov, I. Gushchina, N. Dyrkheeva, V. Svedas, N. Salakhutdinov, O. Lavrik
    Tyrosyl-DNA phosphodiesterase 1 inhibitors: usnic acid enamines enhance the cytotoxic effect of camptothecin
    J. Nat. Prod., 2016, 79 (11), pp 2961-2967 doi:10.1021/acs.jnatprod.6b00979, IF=3.661
  7. T. Khomenko, A. Zakharenko, T. Odarchenko, H.J. Arabshahic, V. Sannikova, O. Zakharova, D. Korchagina, J. Reynisson, K. Volcho, N. Salakhutdinov, O. Lavrik
    New inhibitors of tyrosyl-DNA phosphodiesterase I (Tdp 1) combining 7-hydroxycoumarin and monoterpenoid moieties
    Bioorganic & Medicinal Chemistry, 2016, V. 24, N 21, Pp 5573-5581 doi:10.1016/j.bmc.2016.09.016, IF=2.923
  8. O.S. Patrusheva, V.V. Zarubaev, A.A. Shtro, Ya.R. Orshanskaya, S.A. Boldyrev, I.V. Ilyina, S.Yu. Kurbakova, D.V. Korchagina, K.P. Volcho, N.F. Salakhutdinov
    Anti-influenza activity of monoterpene-derived substituted hexahydro-2H-chromenes
    Bioorganic & Medicinal Chemistry, 2016, V. 24, N 21, Pages 5158-5161 doi:10.1016/j.bmc.2016.08.037, IF=2.923
  9. S.S. Laev, N.F. Salakhutdinov, O.I. Lavrik
    Tyrosyl-DNA phosphodiesterase inhibitors: Progress and potential
    Bioorganic & Medicinal Chemistry, 2016, V. 24, N 21, Pp 5017-5027 doi:10.1016/j.bmc.2016.09.045, IF=2.923
  10. A.V. Pavlova, E.V. Nazimova, O.S. Mikhal'chenko, I.V. Il'ina, D.V. Korchagina, O.V. Ardashov, E.A. Morozova, T.G. Tolstikova, K.P. Volcho, N.F. Salakhutdinov
    Synthesis and Analgesic Activity of 4,7-Dimethyl-3,4,4a,5,8,8a-Hexahydro-2H-Chromen-4,8-Diols Containing Thiophene Substituents
    Chemistry of Natural Compounds, , 2016, V. 52, N 5, pp 813-820 doi:10.1007/s10600-016-1785-2, IF=0.472
  11. Effect of New Antiviral Agent Camphecin on Behavior of Mice/ A. V. Babina, V. A. Lavrinenko, O. I. Yarovaya, N. F. Salakhutdinov// Bulletin of Experimental Biology and Medicine, January 2017, V. 162, N 3, pp 346-348 doi:10.1007/s10517-017-3612-6, IF=0.448
  12. P. Maki-Arvela, M. Barsukova, I. Winberg, A. Smeds, J. Hemming, K. Eranen, A. Torozova, A. Aho, K. Volcho, D.Yu. Murzin
    Unprecedented Selective Heterogeneously Catalysed “Green” Oxidation of Betulin to Biologically Active Compounds using Synthetic Air and Supported Ru Catalysts
    CHEMISTRYSELECT, V. 1, N 13, August 16, 2016, Pp 3866-3869 doi:10.1002/slct.201600731
  13. A. Sokolova, A. Pavlova, N. Komarova, O. Ardashov, A. Shernyukov, Yu. Gatilov, O. Yarovaya, T. Tolstikova, N. Salakhutdinov
    Synthesis and analgesic activity of new α-truxillic acid derivatives with monoterpenoid fragments
    Medicinal Chemistry Research, 2016, V. 25, N 8, pp 1608-1615 doi:10.1007/s00044-016-1593-z, IF=1.435
  14. Yu.S. Demidova, E.V. Suslov, O.A. Simakova, K.P. Volcho, N.F. Salakhutdinov, I.L. Simakova, D.Yu. Murzin
    Selective one-pot carvone oxime hydrogenation over titania supported gold catalyst as a novel approach for dihydrocarvone synthesis
    Journal of Molecular Catalysis A: Chemical, V. 420, August 2016, Pp 142-148 doi:10.1016/j.molcata.2016.04.013, IF=3.957
  15. E. Nazimova, A. Pavlova, O. Mikhalchenko, I. Il'ina, D. Korchagina, T. Tolstikova, K. Volcho, N. Salakhutdinov
    Discovery of highly potent analgesic activity of isopulegol-derived (2R,4aR,7R,8aR)-4,7-dimethyl-2-(thiophen-2-yl)octahydro-2H-chromen-4-ol
    Medicinal Chemistry Research, 2016, V. 25, N 7, pp 1369-1383 doi:10.1007/s00044-016-1573-3, IF=1.435
  16. E.V. Sharova, G.K. Genkina, N.M. Vinogradova, O.I. Artyushin, O.I. Yarovaya, V.K. Brel
    Phosphorylation of natural productsCytisine, anabasine, and camphor using click chemistry methodology
    Phosphorus, Sulfur, and Silicon and the Related Elements, 2016, V. 191, N 11-12, Pp 1556-1557 (21st International Conference on Phosphorus Chemistry (ICPC-2016),Kazan, RUSSIA, JUN 05-10, 2016 doi:10.1080/10426507.2016.1213257, IF=0.722
  17. Biological activity of usnic acid and its derivatives: Part 2. effects on higher organisms. Molecular and physicochemical aspects/ O. A. Luzina , N. F. Salakhutdinov// Russian Journal of Bioorganic Chemistry, 2016, V. 42, N 3, pp 249-268 doi:10.1134/S1068162016030109, IF=0.66
  18. I.V. Il'ina, K.P. Volcho, D.V. Korchagina, N.F. Salakhutdinov
    The Convenient Way for Obtaining Geranial by Acid-Catalyzed Kinetic Resolution of Citral
    Helvetica Chimica Acta, 2016, V. 99, N 5, Pp 373-377 doi:10.1002/hlca.201500266, IF=1.87
  19. O.S. Mikhalchenko, D.V. Korchagina, K.P. Volcho, N.F. Salakhutdinov
    A practical way to synthesize chiral fluoro-containing polyhydro-2H-chromenes from monoterpenoids
    Beilstein J. Org. Chem. 2016, 12, 648-653 doi:10.3762/bjoc.12.64, IF=2.697
  20. M.N. Timofeeva, V.N. Panchenko, K.P. Volcho, S.V. Zakusin, V.V. Krupskaya, A. Gil, O.S. Mikhalchenko, M.A. Vicente
    Effect of acid modification of kaolin and metakaolin on Bronsted acidity and catalytic properties in the synthesis of octahydro-2H-chromen-4-ol from vanillin and isopulegol
    Journal of Molecular Catalysis A: Chemical, , V. 414, April 2016, Pp 160-166 doi:10.1016/j.molcata.2016.01.010, IF=3.957
  21. Biological activity of usnic acid and its derivatives: Part 1. Activity against unicellular organisms/ O. A. Luzina , N. F. Salakhutdinov// Russian Journal of Bioorganic Chemistry, March 2016, V. 42, N 2, pp 115-132 doi:10.1134/S1068162016020084, IF=0.66
  22. Synthesis and cytotoxic activity of usnic acid cyanoethyl derivatives/ M. E. RakhmanovaO. A. LuzinaEmail authorM. A. PokrovskiiA. G. PokrovskiiN. F. Salakhutdinov// Russian Chemical Bulletin, February 2016, V. 65, N 2, pp 566-569 doi:10.1007/s11172-016-1338-7, IF=0.578
  23. V.P. Sivcev, K.P. Volcho, N.F. Salakhutdinov, V.I. Anikeev
    Unusual transformations of aliphatic nitro compounds in a flow reactor in high-pressure isopropanol on alumina. Part 2. Formation of esters
    The Journal of Supercritical Fluids, V. 107, January 2016, Pages 179-181 doi:10.1016/j.supflu.2015.08.007, IF=2.578
  24. K.S. Kovaleva, A.A. Kononova, V.A. Korobeynikov, S.V. Cheresiz, V.V. Zarubaev, A.A. Shtro, Ya.R. Orshanskaya, O.I. Yarovaya, A.G. Pokrovsky, N.F. Salakhutdinov
    Cytotoxic and Antiviral Properties of Novel Dehydroabietylamine Salts
    Med Chem (Los Angeles) 6:10, 642-646 doi:10.4172/2161-0444.1000408

2015
  1. M. Stekrova, P. Maki-Arvela, N. Kumar, E. Behravesh, A. Aho, Q. Balme, K.P. Volcho, N.F. Salakhutdinov, D.Yu. Murzin
    Prins cyclization: Synthesis of compounds with tetrahydropyran moiety over heterogeneous catalysts
    Journal of Molecular Catalysis A: Chemical, V. 410, 15 December 2015, P 260-270 doi:10.1016/j.molcata.2015.09.021, IF=3.615
  2. A. Torozova, P. Maki-Arvela, N. Kumar, A. Aho, A. Smeds, M. Peurla, R. Sjoholm, I. Heinmaa, K.P. Volcho, N.F. Salakhutdinov, D.Y. Murzin
    Isomerization of verbenol oxide to a diol with para-menthane structure exhibiting anti-Parkinson activity
    Reaction Kinetics, Mechanisms and Catalysis, 2015, V. 116, N 2, pp 299-314 doi:10.1007/s11144-015-0903-7, IF=1.169
  3. K. Ponomarev, A. Pavlova, E. Suslov, O. Ardashov, D. Korchagina, A. Nefedov, T. Tolstikova, K. Volcho, N. Salakhutdinov
    Synthesis and analgesic activity of new compounds combining azaadamantane and monoterpene moieties
    Medicinal Chemistry Research, 2015, V. 24, N 12, pp 4146-4156 doi:10.1007/s00044-015-1464-z, IF=1.401
  4. Synthesis and cytotoxic activity of substituted hexahydro-2H-4,6-(epoxymethano)chromen-8(5H)-ones obtained from (-)-verbenone/ I. V. Il'ina, M. A. Pokrovsky, O. S. Mikhalchenko, D. V. Korchagina, K. P. Volcho, A. G. Pokrovsky, N. F. Salakhutdinov// Russian Chemical Bulletin, 2018, V. 64, N 9, pp 2257-2260 doi:10.1007/s11172-015-1148-3, IF=0.481
  5. E.A. Kulikova, E.Y. Bazhenova, N.K. Popova, T.M. Khomenko, K.P. Volcho, N.F. Salakhutdinov, A.V. Kulikov
    Effect of Acute Administration of 8-(Trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine Hydrochloride (TC-2153) on Biogenic Amines Metabolism in Mouse Brain
    Letters in Drug Design & Discovery, 2015, V. 12, N 10, Pp 833 - 836 doi:10.2174/1570180812666150522221634, IF=0.769
  6. A.S. Sokolova, О.I. Yarovaya, А.V. Shernyukov, Yu.V. Gatilov, Yu.V. Razumova, V.V. Zarubaev, T.S. Tretiak, А.G. Pokrovsky, O.I. Kiselev, N.F. Salakhutdinov
    Discovery of a new class of antiviral compounds: Camphor imine derivatives
    European Journal of Medicinal Chemistry, V. 105, 13 November 2015, Pp 263-273 doi:10.1016/j.ejmech.2015.10.010, IF=3.447
  7. H.J. Arabshahi, M. Rensburg, L.I. Pilkington, C.Y. Jeon, M. Song, L. Gridel, E. Leung, D. Barker, M. Vuica-Ross, K.P. Volcho, A.L. Zakharenko, O.I. Lavrikef, J. Reynisson
    A synthesis, in silico, in vitro and in vivo study of thieno[2,3-b]pyridine anticancer analogues
    MedChemComm, 2015, V. 6, N 11, Pp 1987-1997 doi:10.1039/c5md00245a, IF=2.494
  8. A. Pavlova, O. Mikhalchenko, A. Rogachev, I. Il'ina, D. Korchagina, Yu. Gatilov, T. Tolstikova, K. Volcho, N. Salakhutdinov
    Synthesis and analgesic activity of stereoisomers of 2-(3(4)-hydroxy-4(3)-methoxyphenyl)-4,7-dimethyl-3,4,4a,5,8,8a-hexahydro-2H-chromene-4,8-diols
    Medicinal Chemistry Research, 2015, V 24, N 11, pp 3821-3830 doi:10.1007/s00044-015-1426-5, IF=1.401
  9. E.V. Suslov, K.Yu. Ponomarev, A.D. Rogachev, M.A. Pokrovsky, A.G. Pokrovsky, M.B. Pykhtina, A.B. Beklemishev, D.V. Korchagina, K.P. Volcho, N.F. Salakhutdinov
    Compounds Combining Aminoadamantane and Monoterpene Moieties: Cytotoxicity and Mutagenic Effects
    Medicinal Chemistry, V. 11, N 7, Pp 629 - 635 doi:10.2174/1573406411666150518110053, IF=1.363
  10. Inhibitory properties of nitrogen-containing adamantane derivatives with monoterpenoid fragments against tyrosyl-DNA phosphodiesterase 1/ A.L. Zakharenko, K.U. Ponomarev, E.V. Suslov, D.V. Korchagina, K.P. Volcho, I.A. Vasil'eva, N.F. Salakhutdinov, O.I. Lavrik// Russian Journal of Bioorganic Chemistry, November 2015, V. 41, N 6, pp 657-662 doi:10.1134/S1068162015060199, IF=0.535
  11. CATALYTIC SYNTHESIS OF DIOXINOL WITH ANTICONVULSANT ACTIVITY/ A.S. Torozova, E.M. Sulman, P.V. Sinitsyna, P. Maki-Arvela, K.P. Volcho, D.Yu., Murzin, I. Yu. Tiamina// Научно-технический вестник Поволжья. 2015. № 5. С. 88-90.
  12. O.V. Ardashov Yu. S. Demidova, D.V. Korchagina, K.P. Volcho, I.L. Simakova, N.F. Salakhutdinov
    The First Synthesis of (4S,5R,6R)-5,6-Dihydroxy-4-(prop-1-en-2-yl)cyclohex-1-ene-1-carboxylic Acid
    Helvetica Chimica Acta, V. 98, N 10, Pp 1442-1455 doi:10.1002/hlca.201500125, IF=1.138
  13. M.N. Timofeeva, V.N. Panchenko, A. Gil, S.V. Zakusin, V. V. Krupskaya, K.P. Volcho, M.A. Vicente
    Effect of structure and acidity of acid modified clay materials on synthesis of octahydro-2H-chromen-4-ol from vanillin and isopulegol
    Catalysis Communications, 2015, V. 69, , Pp 234-238 doi:10.1016/j.catcom.2015.07.005, IF=3.698
  14. I.V. Nechepurenko, U.A. Boyarskikh, M.V. Khvostov, D.S. Baev, N.I. Komarova, M.L. Filipenko, T.G. Tolstikova, N.F. Salakhutdinov
    Hypolipidemic Berberine Derivatives with a Reduced Aromatic Ring C
    Chemistry of Natural Compounds, 2015, V 51, N 5, pp 916-922 doi:10.1007/s10600-015-1447-9, IF=0.509
  15. V.V. Zarubaev, A.V. Garshinina, T.S. Tretiak, V.A. Fedorova, A.A. Shtro, A.S. Sokolova, O.I. Yarovaya, N.F. Salakhutdinov
    Broad range of inhibiting action of novel camphor-based compound with anti-hemagglutinin activity against influenza viruses in vitro and in vivo
    Antiviral Research, V. 120, 2015, Pp 126-133 doi:10.1016/j.antiviral.2015.06.004, IF=3.938
  16. I.I. Popadyuk, A.V. Markov, O.V. Salomatina, E.B. Logashenko, A.V. Shernyukov, M.A. Zenkova, N.F. Salakhutdinov
    Synthesis and biological activity of novel deoxycholic acid derivatives
    Bioorganic & Medicinal Chemistry, V. 23, N 15, 2015, Pp 5022-5034 doi:10.1016/j.bmc.2015.05.012, IF=2.792
  17. V.P. Sivcev, K.P. Volcho, N.F. Salakhutdinov, V.I. Anikeev
    Unique shortening of carbon chain during reduction of aliphatic nitro compounds to amines in the presence of supercritical isopropanol on alumina
    The Journal of Supercritical Fluids, V.103, 2015, Pp 101-104 doi:10.1016/j.supflu.2015.04.029, IF=2.371
  18. O.B. Bekker, D.N. Sokolov, O.A. Luzina, N.I. Komarova, Yu.V. Gatilov, S.N. Andreevskaya, T.G. Smirnova, D.A. Maslov, L.N. Chernousova, N.F. Salakhutdinov, V.N. Danilenko
    Synthesis and activity of (+)-usnic acid and (-)-usnic acid derivatives containing 1,3-thiazole cycle against Mycobacterium tuberculosis
    Medicinal Chemistry Research, 2015, V. 24, N 7, pp 2926-2938 doi:10.1007/s00044-015-1348-2, IF=1.401
  19. S.S. Laev, N.F. Salakhutdinov
    Anti-arthritic agents: Progress and potential
    Bioorganic & Medicinal Chemistry, 2015, V. 23, N 13, Pp. 3059-3080 doi:10.1016/j.bmc.2015.05.010, IF=2.793
  20. O.A. Luzina, D.N. Sokolov, M.A. Pokrovskii, A.G. Pokrovskii, O.B. Bekker, V.N. Danilenko, N.F. Salakhutdinov
    Synthesis and Biological Activity of Usnic Acid Enamine Derivatives
    Chemistry of Natural Compounds, July 2015, V. 51, N 4, pp 646-651 doi:10.1007/s10600-015-1376-7, IF=0.509
  21. O. V. Ardashov, D. V. Korchagina, K. P. Volcho, N. F. Salakhutdinov
    Synthesis of 10-Carbonyl and 10-Carboxylic Derivatives of para -Mentha-1,8-Diene-5,6-Diol
    Chemistry of Natural Compounds, 2015, V. 51, N 3, pp 483-487 doi:10.1007/s10600-015-1320-x, IF=0.509
  22. A. Zakharenko, T.Khomenko, S. Zhukova, O. Koval, O. Zakharova, R. Anarbaev, N. Lebedeva, D.Korchagina, N. Komarova, V.Vasiliev, J.Reynisson, K. Volcho, N. Salakhutdinov, O. Lavrik
    Synthesis and biological evaluation of novel tyrosyl-DNA phosphodiesterase 1 inhibitors with a benzopentathiepine moiety
    Bioorganic & Medicinal Chemistry, V. 23, N 9, 2015, Pp 2044-2052 doi:10.1016/j.bmc.2015.03.020, IF=2.793
  23. INFLUENCE OF simvaglyzin ON expression AND INHIBITION of HMG-CoA reductase in rats liver/ Yu.I. Ragino, V.A. Vavilin, E.M. Stakhneva, N.F. Salakhutdinov, O.G. Safronova, A.B. Shintyapina, V.V. Lyakhovich, Yu.P. Nikitin// Атеросклероз. 2015. Т. 11. № 2. С. 14-19.
  24. S. Yu. Kurbakova, I. V. Il'ina, O. S. Mikhalchenko, M. A. Pokrovsky, D. V. Korchagina, K. P. Volcho, A. G. Pokrovsky, N. F. Salakhutdinov
    The short way to chiral compounds with hexahydrofluoreno[9,1-bc]furan framework: Synthesis and cytotoxic activity
    Bioorganic & Medicinal Chemistry, V. 23, N 7, 2015, Pp 1472-1480. doi:10.1016/j.bmc.2015.02.013, IF=2.793
  25. Yu.S. Demidova, E.V. Suslov, O.A. Simakova, I.L. Simakova, K.P. Volcho, N.F. Salakhutdinov, D.Yu. Murzin
    Selective carvone hydrogenation to dihydrocarvone over titania supported gold catalyst
    Catalysis Today, Volume 241, Part B, 1 March 2015, Pages 189-194 doi:10.1016/j.cattod.2014.03.053, IF=3.893
  26. M.N. Timofeeva, K.P. Volcho, O.S. Mikhalchenko, V.N. Panchenko, V.V. Krupskaya, S.V. Tsybulya, A. Gilg, Mi.A. Vicente, N.F. Salakhutdinov
    Synthesis of octahydro-2H-chromen-4-ol from vanillin and isopulegol over acid modified montmorillonite clays: Effect of acidity on the Prins cyclization
    Journal of Molecular Catalysis A: Chemical, V. 398 Pp 26-34 doi:10.1016/j.molcata.2014.11.016, IF=3.615
  27. E.V. Suslov, D.V. Korchagina, M.A. Pokrovskii, A.G. Pokrovskii, K.P. Volcho, N.F. Salakhutdinov
    Synthesis and Cytotoxic Activity of Aza-Michael Reaction Products from Ethyl Sorbate and Heterocyclic Amines
    Chemistry of Natural Compounds, March 2015, Volume 51, Issue 2, pp 296-301 doi:10.1007/s10600-015-1264-1, IF=0.509
  28. Curare-like camphor derivatives and their biological activity/ A. S. Sokolova, E. A. Morozova, V. G. Vasilev, O. I. Yarovaya, T. G. Tolstikova, N. F. Salakhutdinov// Russian Journal of Bioorganic Chemistry, March 2015, Volume 41, Issue 2, pp 178-185 doi:10.1134/S1068162015020156, IF=0.535
  29. Reduction of nitrotoluenes in supercritical isopropanol over Al2O3/ V. P. Sivcev, D. V. Korchagina, K. P. Volcho, N. F. Salakhutdinov, V. I. Anikeev// Russian Journal of Physical Chemistry A, February 2015, Volume 89, Issue 2, pp 202-206 doi:10.1134/S0036024415020314, IF=0.562
  30. А.С. Торозова, Э.М. Cульман, П. Мяки-Арвела, К.П. Волчо, Н.Ф. Салахутдинов, Д.Ю. Мурзин
    Исследование мезопористых структур МСМ-41 и МСМ-48 в синтезе биологически активного вещества для лечения болезни Паркинсона
    Вестник Тверского государственного университета. Серия: Химия. 2015. № 2. С. 31-37.
  31. A. Torozova, P. Maki-Arvela, A. Aho, N. Kuma, A. Smeds, M. Peurla, R. Sjoholm, I. Heinmaa, D.V. Korchagina, K.P. Volcho, N.F. Salakhutdinov, D.Yu. Murzin
    Heterogeneous catalysis for transformation of biomass derived compounds beyond fuels: Synthesis of monoterpenoid dioxinols with analgesic activity
    Journal of Molecular Catalysis A: Chemical, Volume 397, February 2015, Pages 48-55 doi:10.1016/j.molcata.2014.10.023, IF=3.615
  32. A.D. Rogachev, N.F. Salakhutdinov
    Chemical Composition of Pinus sibirica (Pinaceae)
    Chemistry & Biodiversity, 2015, V. 12, N 1, pp 1-53 doi:10.1002/cbdv.201300195, IF=1.515
  33. A. Torozova, P. Maki-Arvela, N.D. Shcherban, N. Kumar, A. Aho, M. Stekrova, K. Maduna Valkaj, P. Sinitsyna, S.M. Filonenko, P.S. Yaremov, V.G. Ilyin, K.P. Volcho, N.F. Salakhutdinov, D.Yu. Murzin
    Effect of acidity and texture of micro-, mesoporous and hybrid micromesoporous materials on the synthesis of paramenthanic diol exhibiting anti-Parkinson activity
    Catalysis, Structure & Reactivity, Volume 1, Issue 3, 2015, pages 146-154 doi:10.1179/2055075815Y.0000000009
  34. Comparison of Behavioral Effects of Fluoxetine, Imipramine and New Psychotropic Drug TC-2153 on Mice with Hereditary Predisposition to Catalepsy/ E. A. Kulikova , M. A.Nikhonova, K.P. Volcho, T.M. Khomenko, N.F. Salakhutdinov, A.V. Kulikov, N.K. Popova// ZHURNAL VYSSHEI NERVNOI DEYATELNOSTI IMENI I P PAVLOVA , 2015, V.65, N 1, Pp. 105-112 doi:10.7868/S0044467715010050
  35. Anti-ulcer agents: chemical aspect of solving the problem/ L N Rogoza and N F Salakhutdinov// Russian Chemical Reviews(2015),84(1):98 doi:10.1070/RCR4430, IF=2.318