В журналу ACS Sustainable Chem. Eng. (IF 6,97) опубликована статья с участием сотрудницы Института д.х.н. М.В. Еделевой (снс, ЛМР):
No Catalyst Added Hydrogen Peroxide Oxidation of Dextran: An Environmentally Friendly Route to Multifunctional Polymers
Ekaterina V. Pronina, Yuri A. Vorotnikov, Tatiana N. Pozmogova, Anastasiya O. Solovieva, Svetlana M. Miroshnichenko, Pavel E. Plyusnin, Denis P. Pishchur, Ilia V. Eltsov, Mariya V. Edeleva, Michael A. Shestopalov, Olga A. EfremovaACS Sustainable Chem. Eng. 2020, 8, 13, 5371-5379,
Publication Date:March 16, 2020
https://doi.org/10.1021/acssuschemeng.0c01030
Abstract
The paper demonstrates a “greener” oxidation of dextran polymer of various molecular masses, the component of many industrially and pharmaceutically important materials, by aqueous H2O2 in a no catalyst added setting that produced a multifunctional oxidized dextran. Specifically, on the top of common functional groups (hydroxo, carbonyl, and carboxylic acids), the freshly peroxide oxidized dextran had also a significant number of peroxo-groups, which endowed the polymer with significant cytotoxic properties, as demonstrated on a larynx carcinoma cell line. We also have shown that the peroxo-groups could be easily removed in an alkaline media to yield nontoxic oxidized dextran polymers.
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