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N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry
Siberian Branch of Russian Academy of Science





Description and properties

 A  new antiviral agent applicable in HIV-1 therapy has been developed in N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry in collaboration with the Institute of Chemical-Energy Technologies of Siberian Branch of RAS, Institute of Petrochemistry and Catalysis of RAS and Vektor StateScientific Center of Virology and Biotechnology. The compound is synthesized from natural triterpene  betuline – available metabolite of birch bark. Anti-HIV activity of the agent is substantially higher than that of azidothimidine.


Technical-Economic Advantages

  • Low-toxic inhibitor of embedding the virus into the cell
  • Technologically simple. Obtained on the basis of available plant material, which provides at least fivefold decrease in the cost of the annual therapy 


  • Anti-HIV agent
  • Immunostimulant
  • Antiherpetic


Patent of RF № 2211843 of 25.01.2002. “N`-{N-[3-oxo-20(29)-lupene-28-oyl]-9-aminononanoyl}-3-amino-3-phenylpropionic acid with immunopotentiating and antiviral activity.

Practical realization

  • The main part of pre-clinical testing is completed
  • Pilot plant schedule is developed


N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry,
Siberian Branch of the Russian Academy of Sciences
9, Acad. Lavrentiev Ave,  630090, Novosibirsk, 90, Russsia
PhD< E.E. Shults , Head of the Laboratory
Tel.: (383) 330-85-33          E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.