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N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry
Of the Siberian Branch of Russian Academy of Science

Mezenkova

Head -  Dr. Sci. (Chem) Tatyana Vladimirovna Mezenkova

Phone: (383) 330-69-43, internal phone: 2-90
email:This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Laboratory was founded in 1960 by Corresponding Member, Prof. N.N. Vorozhtsov and Dr. G.G. Yakobson. Up to the middle of 2015 Laboratory was headed by prof. V.E. Platonov

 The major scientific trends


  • development of the scientific principles of the synthesis and functionalization of polyfluoroarenes, investigation of their reactivity and the mechanistic details, including observations of intermediates and study of their properties, looking for the areas of practical applications of polyfluoroarenes;
  • investigation of the processes of functionalization of polyfluoroarenes on the basis of organometallic compounds;
  • transformations of fluoroalkyl, fluorovinyl, nitrogen-, oxygen-, and sulfur-containing functional groups.
 

Staff

Employee Position Room Phone Phone in. email Publications
by yearsby tipeby If
1 Mezhenkova Tatyana Vladimirovna Lab's Head (Doct. Chem) 203, 404 НТК 330-69-43 2-90, 3-65 This email address is being protected from spambots. You need JavaScript enabled to view it.
2 Karpov Viktor Mikhailovich Chief Researcher (Doct. Chem.) 203 330-69-43 2-90 This email address is being protected from spambots. You need JavaScript enabled to view it.
3 Platonov Вячеслав Evdokimovich Chief Researcher (Doct. Chem.) 316 НТК 330-94-37 2-87 This email address is being protected from spambots. You need JavaScript enabled to view it.
4 Bardin Vadim Viktorovich Leading Researcher (Doct. Chem) 211 330-94-32 2-98 This email address is being protected from spambots. You need JavaScript enabled to view it.
5 Zonov Yaroslav Viktorovich Senior Researcher (Cand. Chem.) 203 330-69-43 2-90 This email address is being protected from spambots. You need JavaScript enabled to view it.
6 Kovtonyuk Vladimir Nikolaevich Senior Researcher (Cand. Chem.) 229 330-69-43 3-94 This email address is being protected from spambots. You need JavaScript enabled to view it.
7 Maksimov Alexander Mikhailovich Senior Researcher (Cand. Chem.) 228 330-69-43 2-23 This email address is being protected from spambots. You need JavaScript enabled to view it.
8 Bredikhin Roman Andreevich Researcher (Cand. Chem.) 317, 230 330-78-60, 330-69-43 2-71, 3-97 This email address is being protected from spambots. You need JavaScript enabled to view it., This email address is being protected from spambots. You need JavaScript enabled to view it.
9 Vinogradov Andrey Sergeevich Researcher (Cand. Chem.) 326 330-69-43 3-85 This email address is being protected from spambots. You need JavaScript enabled to view it.
10 Nikul'shin Pavel Viktorovich Researcher (Cand. Chem.) 230 330-69-43 3-97 This email address is being protected from spambots. You need JavaScript enabled to view it.
11 Sinyakov Vladimir Рейнович Leading Engineer 203 330-69-43 2-90 This email address is being protected from spambots. You need JavaScript enabled to view it.
12 Tarasova Nadezhda Pavlovna Senior Laboratory Assistant 230 330-69-43 3-97
Students
13 Golokhvostova Darya Sergeevna laboratory assistant 203 330-69-43 2-90 This email address is being protected from spambots. You need JavaScript enabled to view it.
14 Komarov Vladislav laboratory assistant 203 330-69-43 2-90 This email address is being protected from spambots. You need JavaScript enabled to view it.
 

Scientific achievements (recent)


 
  • New area of the chemistry of aromatic compounds – the chemistry of polyfluoroarenes and their analogs has been created;
  • General method for the synthesis of the key polyfluoroaromatic compounds and their functional derivatives, based on the high-temperature exchange the chlorine atoms of polychlorinated arenes for fluorine ones by the action of potassium fluoride has been developed;
  • The common reaction regularities of polyfluoroarenes with electrophilic, nucleophilic and radical reagents and carbenes have been studied;
  • Original methods for the synthesis of polyfluoroaromatic derivatives and new approaches for polyfluoroarene synthesis, based on transformations with the rearrangement of the molecular skeleton as a result of thermal intramolecular radical cyclization, and also cycle contraction, expansion or opening in the course of cationic transformations of polyfluorinated benzocycloalkenes and their carbonyl derivatives have been developed;
  • Modifications and transformations of the polyfluorinated ring, including the subsequent rearomatisation, and involving synthesis and transformartions of reactive polyfluorocyclohexadienones in chemical and photochemical processes have been studied;
  • On the basis of the co-pyrolysis of polyfluoroarenethiols with chlorine or bromine at 400-500°С in a flow system new method of synthesis of a wide variety of chloro- and bromopolyfluoroarenes has been developed;
  • Original method of synthesis of polyfluoroaromatic organozinc compounds has been developed, their chemistry is being investigated.
  •  

Nowadays our research activities are focused on the following fields:


 
  • Priority direction V.36. “Theoretical chemistry and development of the methodology of organic and inorganic synthesis, new physical-chemical methods of investigations”;
  • Program V.36.6 “The development of the scientific basis of organic, elementorganic and inorganic synthesis for elaboration of racional methods for the synthesis of biologically active compounds, synthones, monomers and polymers of high-technological products”.
 

Current projects


 

Laboratory investigations were partly supported by grants of Presidium RAS, Presidium SB RAS, Russian Foundation of Basic Research, Russian noncommercial partnership “ASGL – investigation laboratories”, DFG, Volkswagen-Stiftung (Germany) and also by different contracts.
At present time the investigations are supported by RFBR grant.

Recent publications (main)


  1. N.N. Vorozhtsov-Junior, V.E. Platonov, G.G. Yakobson. The synthesis of hexafluorobenzene from hexachlorobenzene. Russ. Chem. Bull. Chemical Series, 1524 (1963).
  2. N.G. Malyuta, V.E. Platonov, G.G. Furin, G.G. Yakobson. Copyrolysis of pentafluorosubstituted derivatives of benzenes with sources of difluorocarbene. Formation of perfluoroindan. Tetrahedron, 31, 1201 (1975).
  3. V.M. Karpov, V.E. Platonov, G.G. Yakobson. The generation of polyfluoroindenyl cations. On the aromaticity of polyfluoroindenyl cations. Tetrahedron, 34, 3215 (1978).
  4. The reactivity of polyfluoroaromatic compounds (Ed. G.G. Yakobson). Novosibirsk, Nauka, 1983 // Реакционная способность полифторароматических соединений (Под ред. Г.Г. Якобсона). Изд-во «Наука», Новосибирск, 1983.
  5. V.I. Krasnov, V.E. Platonov, I.V. Beregovaya, L.N. Shchegoleva. Transformation of perfluoroxylenes and perfluoro-p-cumene under the action of Zn(Cu)-DMF-H2O. Tetrahedron, 53, 1797 (1997).
  6. L.S. Kobrina. Fluorinated cyclohexadienones – the universal synthones for obtaining of fluororganic compounds. Russ. Chem. Bull. Chemical Series, 1629 (2002).
  7. T.D. Petrova, V.E. Platonov. Polyfluoroaromatic compounds with a –N=CClR group – a reactive type of polyfluoroarenes. J. Fluorine Chem. 126, 860 (2005).
  8. Krasnov V.I., Vinogradov A.S., Platonov V.E. Preparation of organozinc compounds from 3-chloroheptafluorotoluene and zinc: the participation of C-F bonds. Mendeleev Commun., 168 (2006).