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N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry
Of the Siberian Branch of Russian Academy of Science

Department of Medical Chemistry


Толстикова Т.Г.


Head - Professor, Dr. Sci. Tatiana Genrikhovna Tolstikova

Phone: (383) 330-07-31
internal phone: 2-49
email:This email address is being protected from spambots. You need JavaScript enabled to view it.

 

The laboratory of pharmacological investigations was founded in 2000. From that moment more than 1000 novel compounds were tested by 60 experimental animal models, among them perspective opioid analgesic, antidepressant, nootropic, anxiolytic, anticonvulsant, muscle relaxant, hepatoprotector, cytostatic toxic effects corrector, antihypertensive, antiarrhythmic, antiulcer, anti-inflammatory, anti- hypercholesterolemia and antioxidant compounds were disclosed. Also compounds for the MR-tomography and nano-aerosol forms of water insoluble drugs were developed.

Resercher ares
 

Research areas:

The toxic-pharmacological investigation of low-molecular plant metabolites and their synthetic derivatives with the goal of original medications creation.

Plant metabolites chemistry. Medicinal chemistry. Pharmacological properties and mechanism of action investigation of novel drug agents of natural or synthetic origin.

 Pharmacological properties and mechanism of action investigation of novel drug agents derived by clathration with glycosides and polysaccharides.

Cytoprotective and antitumoral agents search among triterpenoids.

In vivo and in vitro investigation of analgesic, psychotropic and cardiotropic agent’s properties.

Pharmacological screening of novel biologically active plant and synthetic compounds.   

 

Main scientific results:

  • More than 1000 new compounds were investigated
  • More than 200 articles and 4 books were published
  •  12 PhD theses and 2 doctoral theses were defended
  • Next promising agents were found: “BETAMID”, “GLYCIDIPIN”, “FLUOGLISIN”, “DIOL”, “RNA-sin”, “BISULFAMIN”, “METILAN”, “FURALANIN”. 

 

STAFF

Staff

Employee Position Room Phone Phone in. email Publications
by years
1 Tolstikova Tatyana Genrikhovna Lab's Head (Doct. Biol.) М-3 330-07-31 2-49 This email address is being protected from spambots. You need JavaScript enabled to view it.
2 Sorokina Irina Vasilievna Leading Researcher (Doct.Biology) М-5, М-25 330-36-63 3-55 This email address is being protected from spambots. You need JavaScript enabled to view it.
3 Zhukova Natalia Anatolievna Leading Researcher (Doct. Med.) М-7 330-36-63 2-50 This email address is being protected from spambots. You need JavaScript enabled to view it.
4 Khvostov Mikhail Vladimirovich М-24 330-36-63 4-34 This email address is being protected from spambots. You need JavaScript enabled to view it.
5 Baev Dmitry Sergeevich Senior Researcher (Cand. Biol.) М-25а 330-36-63 3-55 This email address is being protected from spambots. You need JavaScript enabled to view it.
6 Bryzgalov Arkady Olegovich Senior Researcher (Cand. Biol.) М-4 330-36-63 This email address is being protected from spambots. You need JavaScript enabled to view it.
7 Morozova Ekaterina Aleksandrovna Senior Researcher (Cand. Biol.) М-24 330-36-63 4-34 This email address is being protected from spambots. You need JavaScript enabled to view it.
8 Pavlova Alla Viktorovna Senior Researcher (Cand. Biol.) М-24 330-36-63 4-34 This email address is being protected from spambots. You need JavaScript enabled to view it.
9 An'kov Sergey Vladimirovich Researcher (Cand. Biol.) М-25 330-36-63 3-55
10 Borisov Sergey Alkisovich Researcher (Cand. Biol.) М-25 330-36-63 3-55
11 Borisova Marina Sergeevna Researcher (Cand. Biol.) М-6 330-36-63 2-26 This email address is being protected from spambots. You need JavaScript enabled to view it.
12 Kotlyarova Anastasiya Anatolievna Researcher (Cand. Biol.) М-23, M-24 330-36-63 4-34
13 Dumchenko Natalia Borisovna Junior Researcher
14 Simakova Olga Vladimirovna Junior Researcher
15 Marenina Mariya Konstantinovna Junior Researcher (Cand. Biol.) М-23 330-36-63 4-34
16 Dolgikh Margarita Petrovna Leading Engineer М-6 330-36-63 2-26 This email address is being protected from spambots. You need JavaScript enabled to view it.
17 Kosinova Ul'yana Vladimirovna engineer М-19, М-9 330-36-63 2-14, 2-62 This email address is being protected from spambots. You need JavaScript enabled to view it.
18 Nizomov Sirozhiddin Ashuralievich engineer М-5 330-36-63 3-55
19 Khodakov Anton Anatolievich engineer М-5 330-36-63 3-55
20 Zarembina Marina Fedorovna Senior Laboratory Assistant М-19 330-36-63 2-14
21 Sazonova Lyudmila Vyacheslavovna Senior Laboratory Assistant М-19 330-36-63 2-14
22 Shmakova Ekaterina Sergeevna Senior Laboratory Assistant
23 Savchenko Elena Aleksandrovna technicist М-19 330-36-63 2-14
Students
24 Tverdokhlebov Gleb Aleksandrovich laboratory assistant
PHD Students
25 Zaigraev Vladimir Yurievich engineer М-5 330-36-63 3-55
26 Meshkova Yuliya Vladimirovna engineer



PUBLICATIONS
 
Publications over the past years

 

Laboratory staff publications (DB NIOCh)

Reviews, Articles


2020
  1. E.F. Khusnutdinova, A.V. Petrova, A.N. Lobov, O.S. Kukovinets, D.S. Baev, O.B. Kazakova
    Synthesis of C17-[5-methyl-1,3]-oxazoles by N-propargylation of triterpenic acids and evaluation of their cytotoxic activity
    Natural Product Research (Formerly Natural Product ), Published online: 28 Mar 2020 doi:10.1080/14786419.2020.1744139, IF=2.158
  2. O.I. Brusentseva, Yu.V. Kharitonov, M.P. Dolgikh, T.G. Tolstikova, E.E. Shul'ts
    Synthesis and Analgesic Activity Assessment of Furanolabdanoid Conjugates with Glucuronic Acid
    Chemistry of Natural Compounds, Published: 26 July 2020 doi:10.1007/s10600-020-03119-7, IF=0.653
  3. B.M. Urbagarova, E.E. Shults, V.V. Taraskin, L.D. Radnaeva, T.N. Petrova, T.V. Rybalova, T.S. Frolova, A.G. Pokrovskii, Ja. Ganbaatar
    Chromones and coumarins from Saposhnikovia divaricata (Turcz.) Schischk. Growing in Buryatia and Mongolia and their cytotoxicity
    Journal of Ethnopharmacology, 2020, V. 261, 1125170 doi:10.1016/j.jep.2019.112517, IF=3.69
  4. S.A. Popov, M. D. Semenova, D. S. Baev, T. S. Frolova, E. E.Shults,Ch.Wang, M.Turkse
    Synthesis of cytotoxic urs-12-ene- and 28-nor-urs-12-ene- type conjugates with amino- and mercapto-1,3,4-oxadiazoles and mercapto-1,2,4-triazoles
    Steroids, 2020, V. 153, 108524 doi:10.1016/j.steroids.2019.108524, IF=1.948
  5. Yu.I. Glazachev, A.A. Schlotgauer, V.A. Timoshnikov, P.A. Kononova, O.Yu. Selyutina, E.A. Shelepova, M.V. Zelikman, M.V. Khvostov, N.E. Polyakov
    Effect of Glycyrrhizic Acid and Arabinogalactan on the Membrane Potential of Rat Thymocytes Studied by Potential-Sensitive Fluorescent Probe
    The Journal of Membrane Biology, 2020, V. 253, Pp 343-356 doi:10.1007/s00232-020-00132-3, IF=1.876
  6. V.A. Demina, S.V. Krasheninnikov, A.I. Buzin, R.A. Kamyshinsky, N.V. Sadovskaya, N.Goncharov. Evgeny, N.A. Zhukova, M.V. Khvostov, A.V. Pavlova, T.G. Tolstikova, N.G. Sedush, S.N. Chvalun
    Biodegradable poly(l-lactide)/calcium phosphate composites with improved properties for orthopedics: Effect of filler and polymer crystallinity
    Materials Science and Engineering: C, 2020, V. 112, 110813 doi:10.1016/j.msec.2020.110813, IF=5.88
  7. T.S. Khlebnicova, Yu.A. Piven, F.A. Lakhvich, I.V. Sorokina, T.S. Frolova, D.S. Baev, T.G. Tolstikova
    Betulinic Acid-Azaprostanoid Hybrids: Synthesis and Pharmacological Evaluation as Anti-inflammatory Agents
    Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, (Formerly Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents), 2020, V. 19, N 3, Pp 254-267 doi:10.2174/1871523018666190426152049
  8. NEW APPROACHES TO INCREASING THE EFFECTIVENESS OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS USING NANOSCALE DELIVERY SYSTEMS/ POLYAKOV N. E., VALIULIN S. V., ONISCHUK A. A., TOLSTIKOVA T. G.//
  9. I.А. Novakov, L.L. Brunilina, I.А. Kirillov, M.B. Nawrozkij, M.D. Robinovich, E.S. Titova, D.S. Sheikin, E.А. Ruchko, A.V. Pavlova, A.А. Kotlyarova, T.G. Tolstikova
    The synthesis of new acyclic analogs of 3-phenacyluridine and comparative evaluation of their in vivo biological activity
    Chemistry of Heterocyclic Compounds, Published: 18 July 2020 doi:10.1007/s10593-020-02729-x, IF=1.519
  10. А.А. Бажина, С.В. Валиулин, А М. Бакланов, С.Н. Дубцов, С.В. Аньков, М.Е. Плохотниченко, Т.Г. Толстикова, А.А. Онищук
    Метод генерации аэрозоля антибактериального лекарственного вещества цефазолина
    Оптика атмосферы и океана. 2020. Т. 33. № 6 (377). С. 459-462. doi:10.15372/AOO20200607
  11. N.S. Sirazhetdinova, V.A. Savelyev, T.S. Frolova, D.S. Baev, L.S. Klimenko, I.V. Chernikov, O.S. Oleshko, T.A. Sarojan, A.G. Pokrovskii, E.E. Shults
    1-Hydroxyanthraquinones Containing Aryl Substituents as Potent and Selective Anticancer Agents
    Molecules 2020, 25(11), 2547 doi:10.3390/molecules25112547, IF=3.267
  12. I. Il'ina, E. Morozova, A. Pavlova, D. Korchagina, T. Tolstikova, K. Volcho, N. Salakhutdinov
    Synthesis and analgesic activity of aliphatic ketones-derived chiral hexahydro-2H-chromenes
    Medicinal Chemistry Research, 2020, V. 29, N 4, pp 738-747 doi:10.1007/s00044-020-02518-3, IF=1.783
  13. Study of Plant Coumarins. 18. Coumarin Conjugates with Lupane Triterpenoidsand 1,2,3-triazoles: Synthesis and Anti-inflammatory Activity/ Lipeeva A. V., Dolgikh М. Р., Tolstikova T. G., Shults E. E// Russian Journal of Bioorganic Chemistry, 2010, V. 46, N 2, Pp125-132 doi:10.1134/S1068162020010161, IF=0.682
  14. Study of Plant Coumarins. 18. Coumarin Conjugates with Lupane Triterpenoidsand 1,2,3-triazoles: Synthesis and Anti-inflammatory Activity/ Lipeeva A. V., Dolgikh М. Р., Tolstikova T. G., Shults E. E// Russian Journal of Bioorganic Chemistry, 2010, V. 46, N 2, Pp125-132 doi:10.1134/S1068162020010161, IF=0.682
  15. Synthesis and analgesic activity of 1,3,5-trisubstituted pyrazoles containing a diterpenoid moiety/ M.E. Mironov, A.I. Poltanovich , T.V., Rybalova, M.P. Dolgikh, T.G. Tolstikova, E.E Shults// Russian Chemical Bulletin, 2020, V. 69, Pp 537–546 doi:10.1007/s11172-020-2795-6, IF=1.061
  16. A.A. Kotlyarova, K.Yu. Ponomarev, E.A. Morozova, D.V. Korchagina, E.V. Suslov, A.V. Pavlova, T.G. Tolstikova, K.P. Volcho, N.F. Salakhutdinov
    The effect of 3,7-diazabicyclo[3.3.1]nonanes containing monoterpenoid moieties on the physical activity of mice
    Journal of research in pharmacy, 2020, V. 24, N 2, Pp 196-204 doi:10.35333/jrp.2020.136
  17. Prostatotropic action of glycyrrhizic acid disodium salt in modeling benign prostatic hyperplasia/ Nizomov S.A., Sorokina I.V., Zhukova N.A., Borisov S.A., Tolstikova T.G., Semenov D.E., Bakarev M.A.// Bulletin of Experimental Biology and Medicine doi:10.1007/s10517-020-04836-3, IF=0.775
  18. I. Il'ina, E. Morozova, D. Korсhagina, K. Volсho, T. Tolstikova, N. Salakhutdinov
    Synthesis and Analgesic Activity of Monoterpenoid Aldehyde-derived Hydro-2H-chromeneols
    Letters in Drug Design & Discovery, 2020, V. 17, N 1, Pp 68-78 doi:10.2174/1570180816666181114131220, IF=1.169
  19. A.A. Okhina, A.D. Rogachev, O.I. Yarovaya, M.V. Khvostov, T.G. Tolstikova, A.G. Pokrovsky, V.A. Khazanov, N.F. Salakhutdinov
    Development and validation of an LC-MS/MS method for the quantitative analysis of the anti-influenza agent camphecene in rat plasma and its application to study the blood-to-plasma distribution of the agent
    Journal of Pharmaceutical and Biomedical Analysis, 2020, V. 180, 113039 doi:10.1016/j.jpba.2019.113039, IF=3.209

2019
  1. S.A. Popov, M.D. Semenova, D.S. Baev, T.S. Frolova, M.A. Shestopalov, Ch. Wang, Zh. Qi, E.E. Shults, M. Turks
    Synthesis and cytotoxicity of hybrids of 1,3,4- or 1,2,5-oxadiazoles tethered from ursane and lupane core with 1,2,3-triazole
    Steroids, Available online 17 July 2020, 108698 doi:10.1016/j.steroids.2020.108698, IF=2.135
  2. S.A. Kremis, D.S. Baev, A.V. Lipeeva, E.E. Shults, T.G. Tolstikova, O.I. Sinitsyna, A.V. Kochetov, T.S. Frolova
    Genotoxic activity of 1,2,3-triazolyl modified furocoumarins and 2,3-dihydrofurocoumarins
    Journal of biochemical and molecular toxicology, 2019, V. 33, N 11, e22396 doi:10.1002/jbt.22396, IF=2.965
  3. Application of Natural Polysaccharides in Pharmaceutics/ M.V. Khvostov, T.G. Tolstikova, S.A. Borisov, A.V. Dushkin// Russian Journal of Bioorganic Chemistry, 2019, V. 45, N 6, Pp 438-450 doi:10.1134/S1068162019060219, IF=0.794
  4. O.V. Ardashov, A.V. Pavlova, A.K. Mahato, Yu. Sidorova, E.A. Morozova, D.V. Korchagina, G.E. Salnikov, A.M. Genaev, O.S. Patrusheva, N. Li-Zhulanov, T.G. Tolstikova, K.P. Volcho, N. Salakhutdinov
    A novel small molecule supports the survival of cultured dopamine neurons and may restore the dopaminergic innervation of the brain in the MPTP mouse model of Parkinson's disease
    ACS Chemical Neuroscience, 2019, V. 10, N 10, Pp 4337-4349 doi:10.1021/acschemneuro.9b00396, IF=3.861
  5. S.A. Popov, M.D. Semenova, D.S. Baev, I.V. Sorokina, N.A. Zhukova, T.S. Frolova, T.G. Tolstikova, E.E. Shults, M. Turks
    Lupane-type conjugates with aminoacids, 1,3,4- oxadiazole and 1,2,5-oxadiazole-2-oxide derivatives: synthesis, anti-inflammatory activity and in silico evaluation of target affinity
    Steroids, 2019, V.150, 108443 doi:10.1016/j.steroids.2019.108443, IF=2.136
  6. O. Zakharova, G. Nevinsky, L. Politanskaya, D. Baev, L. Ovchinnikova, E. Tretyakov
    Evaluation of antioxidant activity and cytotoxicity of polyfluorinated diarylacetylenes and indoles toward human cancer cells
    Journal of Fluorine Chemistry, V. 226, October 2019, 109353 doi:10.1016/j.jfluchem.2019.109353, IF=2.055
  7. A. Predtetchinski, E. Predtechenskaya, I. Sorokina, A. Guzev, S. Aydagulov
    Morphologic changes and protective role of prolactin in experimental multiple sclerosis animal model
    MULTIPLE SCLEROSIS JOURNAL, 2019, V.25, S2, Pp 435-435 (P845) (35th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS Местоположение: Stockholm, SWEDEN публ.: SEP 11-13, 2019 Конференция: 35th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS) / 24th Annual MULTIPLE SCLEROSIS JOURNAL Том: 25 Специальный выпуск: SI Приложение: 2 Стр.: 435-435 Аннотация к встрече: P845 Conference of Rehabilitation in MS Местоположение: Stockholm, SWEDEN публ.: SEP 11-13, 2019, IF=5.649
  8. Ultrastructure of the liver exposed to cyclophosphamide and triterpenoids/ O.P. Molodykh, I.V. Sorokina, E.V. Vinogradova, V.I. Kapustina, A.A. Khodakov// Bulletin of Experimental Biology and Medicine, 2020, V. 168, N 3, Pp 400-405 doi:10.1007/s10517-020-04718-8, IF=0.567
  9. Synthesis and Hypoglycemic Activity of Aryl(Hetaryl)Propenoic Cyanopyrrolidine Amides/ S. O. Kuranov, M. E. Blokhin, S. A. Borisov, M. V. Khvostov, O. A. Luzina, N. F. Salakhutdinov// Russian Journal of Bioorganic Chemistry, 2019, V. 45, N 5, pp 374-380 doi:10.1134/S1068162019050078, IF=0.794
  10. Cardioprotective Effect of p-Tyrosol in the Acute Period of Cardiovascular and Cerebral Ischemia/ A.P Krysin, I.V. Sorokina, E.E. Shults// Chemistry for Sustainable Development, 2019, V. 27, N 4, Pp 365-372 (in Russian) doi:10.15372/KhUR2019147
  11. T.S. Khlebnicova, Yu.A. Piven, A.V. Baranovsky, F.A. Lakhvich, I.V. Sorokina, T.G. Tolstikova
    Fluorine-containing lupane triterpenoid acid derivatives: Design, synthesis and biological evaluation as potential anti-inflammatory agents
    Steroids, V.147, July 2019, Pp 62-69 doi:10.1016/j.steroids.2018.10.001, IF=2.136
  12. Supramolecular systems for the delivery of the molecules of medicinal substances based on water-soluble plant metabolites. physicochemical, pharmacological properties and the features of mechanochemical preparation/ Dushkin A.V., Meteleva E.S., Tolstikova T.G., Khvostov M.V., Polyakov N.E., Lyakhov N.Z.// Chemistry for Sustainable Development, 2019. V. 27, № 3. P. 233-244. (in Russian) doi:10.15372/KhUR2019129
  13. D. Avgustinovich, M. Tsyganov, G. Vishnivetskaya, А. Кovner, I. Sorokina, I. Orlovskaya, L. Toporkova, E. Goiman, T. Tolstikova, A. Dushkin, N. Lyakhov, V. Mordvinov
    Effects of supramolecular complexation of praziquantel with disodium glycyrrhizinate on the liver fluke Opisthorchis felineus: an in vitro and in vivo study
    Acta Tropica, 2019, V.194, Pp 1-12 doi:10.1016/j.actatropica.2019.03.017, IF=2.629
  14. T.S. Frolova, A.V. Lipeeva, D.S. Baev, S.I. Baiborodin, К.E. Orishchenko, A.V. Kochetov, O.I. Sinitsyna
    Fluorescent labeling of ursolic acid with FITC for investigation of its cytotoxic activity using confocal microscopy
    Bioorganic Chemistry, 2019, V. 87, Pp 876-887 doi:10.1016/j.bioorg.2018.11.052, IF=3.929
  15. Morphological analysis of prostatotropic activity of (3,5-dimethyl-4-hydroxy) benzyltiodyododecan in the model of benign prostatic hyperplasia in rats/ S.A. Nizomov, I.V. Sorokina, N.A. Zhukova, T.G. Tolstikova, D.E. Semenov, A.E. Prosenko// Bulletin of Experimental Biology and Medicine, 2019, V. 167, N 6, pp 809-812 doi:10.1007/s10517-019-04628-4, IF=0.567
  16. S.V. Valiulin, A.A. Onischuk, A.M. Baklanov, S.N. Dubtsov, S.V. An'kov, T.G. Tolstikova, M.E. Plokhotnichenko, G.G. Dultseva, P.S. Mazunina
    Excipient-free isoniazid aerosol administration in mice: Evaporation-nucleation particle generation, pulmonary delivery and body distribution
    International Journal of Pharmaceutics, 2019, V. 563, Pp 101-109 doi:10.1016/j.ijpharm.2019.03.050, IF=4.213
  17. T.M. Khomenko, D.V. Korchagina, D.S. Baev, P.M. Vassiliev, K.P. Volcho, N.F. Salakhutdinov
    Antimicrobial Activity of Substituted Benzopentathiepin-6-amines
    Journal of Antibiotics, 2019, V. 72, pp 590-599 doi:10.1038/s41429-019-0191-y, IF=2.446
  18. Q. Zhang, L. Suntsova, Yu.S. Chistyachenko, V. Evseenko, M.V. Khvostov, N.E. Polyakov, A.V. Dushkin, W. Su
    Preparation, physicochemical and pharmacological study of curcumin solid dispersion with an arabinogalactan complexation agent
    International Journal of Biological Macromolecules, V. 128, 1 May 2019, Pp 158-166 doi:10.1016/j.ijbiomac.2019.01.079, IF=4.784
  19. A.V. Lipeeva, A.O. Brysgalov, T.G. Tolstikova, E.E. Shults
    Synthesis, Transformations and Characterization of 8 Aminomethyl Substituted Umbelliferones as Probable Anti-Arrhythmic Agents
    Current Bioactive Compounds, 2019, V. 15 , N 1, Pp 71-82 Volume 15 , Issue 1 , 2019 doi:10.2174/1573407213666171030152601
  20. A.V. Lipeeva, D.O. Zakharov, L.G. Burova, T.S. Frolova, D.S. Baev, I.V. Shirokikh, A.N. Evstropov, O.I. Sinitsyna, T.G. Tolsikova, E.E. Shults
    Design, Synthesis and Antibacterial Activity of Coumarin-1,2,3-triazole Hybrids Obtained from Natural Furocoumarin Peucedanin
    Molecules 2019, 24(11), 2126 doi:10.3390/molecules24112126, IF=3.06
  21. Synthesis and analgesic activity of octahydro-2H-chromenols, derivatives of aliphatic ketones/ I. V. Il'ina, D. V. Korchagina, E. A. Morozova, T. G. Tolstikova, K. P. Volcho, N. F. Salakhutdinov// Russian Chemical Bulletin, 2019, V. 68, N 5, pp 1061-1066 doi:10.1007/s11172-019-2520-5, IF=1.014
  22. Synthesis, hypolipidemic and antifungal activity of tetrahydroberberrubine sulfonates/ I. V. Nechepurenko, E. D. Shirokova, M. V. Khvostov, T. S. Frolova, O. I. Sinitsyna, A. M. Maksimov, R. A. Bredikhin, N. I. Komarova, D. S. Fadeev, O. A. Luzina, T. G. Tolstikova, N. F. Salakhutdinova// Russian Chemical Bulletin, 2019, V. 68, N 5, pp 1052-1060 doi:10.1007/s11172-019-2519-y, IF=1.014
  23. Synthesis of (1S)-(+)-camphor-10-sulfonic acid derivatives and investigations in vitro and in silico of their antiviral activity as the inhibitors of fi lovirus infections/ A. S. Sokolova, D. V. Baranova, O. I. Yarovaya, D. S. Baev, O. A. Polezhaeva, A. V. Zybkina, D. N. Shcherbakov, T. G. Tolstikova, N. F. Salakhutdinov// Russian Chemical Bulletin, 2019, V 68, N 5, pp 1041-1046 doi:10.1007/s11172-019-2517-0, IF=1.014
  24. E.S. Meteleva, Yu.S. Chistyachenko, L.P. Suntsova, M.V. Khvostov, N.E. Polyakov, O. YuSelyutina, T.G. Tolstikova, T.S. Frolova, V.A. Mordvinov, Al.V. Dushkin, N.Z. Lyakhov
    Disodium salt of glycyrrhizic acid - A novel supramolecular delivery system for anthelmintic drug praziquantel
    Journal of Drug Delivery Science and Technology, V. 50, April 2019, Pp 66-77 doi:10.1016/j.jddst.2019.01.014, IF=2.606
  25. K.P. Cheremnykh, V.A. Savelyev, M.A. Pokrovskii, D.S. Baev, T.G. Tolstikova, A.G. Pokrovskii, E.E. Shults
    Design, synthesis, cytotoxicity, and molecular modeling study of 2,4,6-trisubstituted pyrimidines with anthranilate ester moiety
    Medicinal Chemistry Research, 2019, V. 28, N 4, pp 545–558 doi:10.1007/s00044-019-02314-8, IF=1.72
  26. D.O. Prima, A.G. Makarov, I.Yu. Bagryanskaya, A.E. Kolesnikov, L.V. Zargarova, D.S. Baev, T.F. Eliseeva, L.V. Politanskaya, A.Yu. Makarov, Yu.G. Slizhov, A. V. Zibarev
    Fluorine-Containing n-6 and Angulaand Linear n-6-n' (n, n' = 5, 6, 7) Diaza-Heterocyclic Scaffolds Assembled on Benzene Core in Unified Way
    ChemistrySelect, 2019, V. 4, N 8, Pp 2383-2386 doi:10.1002/slct.201803970, IF=1.716
  27. I.S. Merenkov, M.S. Myshenkov, Yu.M. Zhukov, Yo. Sato, T.S. Frolova, D.V. Danilov, I.A. Kasatkin, O.S. Medvedev, R.V. Pushkarev, O.I. Sinitsyna, M. Terauchi, I.A. Zvereva, M.L. Kosinova, K. Ostrikov
    Orientation-controlled, low-temperature plasma growth and applications of h-BN nanosheets
    Nano Research, 2019, V. 12, N 1, pp 91-99 doi:10.1007/s12274-018-2185-7, IF=8.515

2018
  1. S. Khlebnikova, Yu.A. Piven', F.A. Lakhvich, T.S. Frolova, I.V. Sorokina, T.G. Tolstikova
    Synthesis and Cytotoxicity of Conjugates of Betulinic Acid and F-Containing 2-Acylcycloalkane-1,3-Diones
    Chemistry of Natural Compounds, 2018, V. 54, N 6, pp 1100-1105 doi:10.1007/s1060, IF=0.449
  2. Synthesis and Anti-Inflammatory Activity of Tyrosol and Its Structural Analogs/ A.P. Krysin, T.G. Tolstikova, M.P., E.E. Shul'ts , L.M. Pokrovskii// Pharmaceutical Chemistry Journal, 2019, V. 52, N 11, pp 907-911 doi:10.1007/s11094-019-01924-1, IF=0.679
  3. I.A. Orlovskaya, L.B. Toporkova, M.N. Lvova, I.V. Sorokina, A.V. Katokhin, G.B. Vishnivetskaya, E.V. Goiman, E.V. Kashina, T.G. Tolstikova, V.A. Mordvinov, D.F. Avgustinovich
    Social Defeat Stress Exacerbates the Blood Abnormalities in Opisthorchis felineus-infected mice
    Experimental Parasitology, 2018, V. 193, Pages 33-44 doi:10.1016/j.exppara.2018.08.004, IF=1.82
  4. R.Kong X. Zhu, E.S. Meteleva, N.E. Polyakov, M.V. Khvostov, D.S. Baev, T.G. Tolstikova, A.V. Dushkin, W. Su
    Atorvastatin calcium inclusion complexation with polysaccharide arabinogalactan and saponin disodium glycyrrhizate for increasing of solubility and bioavailability
    Drug Delivery and Translational Research, 2018, V 8, N 5, pp 1200-1213 doi:10.1007/s13346-018-0565-x, IF=3.394
  5. Studyng the effects of Cantharellus cibarius fungi on Opisthorchis felineus trematode and on parasite host-C57BL/6 inbred mice/ M.A. Tsyganov, G.B. Vishnivetskaya, T.P. Kukina, I.V. Sorokina, M.N. Lvova, M.A. Protsenko, N.E. Kostina, D.F. Avgustinovich// VAVILOVSKII ZHURNAL GENETIKI I SELEKTSII, , 2018, V. 22, N 7, Pp. 856-864 doi:10.18699/VJ18.426
  6. S.O. Kuranov, I.P. Tsypysheva, M.V. Khvostov, L.F. Zainullina, S.S. Borisevich, Yu.V. Vakhitova, O.A. Luzina, N.F. Salakhutdinov
    Synthesis and evaluation of camphor and cytisine-based cyanopyrrolidines as DPP-IV inhibitors for the treatment of type 2 diabetes mellitus
    Bioorganic & Medicinal Chemistry, 2018, V. 26, N 15, Pp 4402-4409 doi:10.1016/j.bmc.2018.07.018, IF=2.881
  7. Physicochemical Properties and Anti-Opisthorchosis Effect of Mechanochemically Synthesized Solid Compositions of Praziquantel with Glycyrrhizic Acid Disodium Salt/ E.S. Meteleva, Yu.S. Chistyachenko, L.P. Suntsova, M.A. Tsyganov, G.B. Vishnivetskaya, D.F. Avgustinovich, M.V. Khvostov, N.E. Polyakov, T.G. Tolstikova, V.A. Mordvinov, A.V. Dushkin, N.Z. Lyakhov// Doklady Biochemistry and Biophysics, 2018, V. 481, N 1, pp 228-231 doi:10.1134/S1607672918040142, IF=0.61
  8. Accessible Metabolites from Siberian Plants for Development and Production of Innovative Drugs/ T.G. Tolstikova, I.V. Sorokina, N.A. Zukova, E.A. Morosova, YU.V. Kharitonov, M.E. Mironov, S.A. Popov, E.E. Shults// doi:10.15372/KhUR20180308
  9. Differentially expressed neurotransmitter genes in the dorsal striatum of male mice with psychomotor disturbances/ D.A. Smagin, A.G. Galyamina, I.L. Kovalenko, V.N. Babenko, N.V. Tamkovich, S.A. Borisov, T.G. Tolstikova, N.N. Kudryavtseva// Zhurnal vysshei nervnoi deyatelnosti imeniI I P Pavlova, 2018, V. 68, N 2, Pp 227-249 doi:10.7868/S0044467718020089, IF=0.31
  10. Antiulcer and anti-inflammatory activity of the campholenic aldehyde-derived thiazolidinone/ BORISOVA Marina Sergeevna, SOKOLOV Dmitriy Nikolaevich, ZHUKOVA Natalya Anatolevna, TOLSTIKOVA Tatyana Genrikhovna, SALAKHUTDINOV Nariman Faridovich// doi:10.15372/SSMJ20180201
  11. Т.С. Фролова, С.Ж. Шарапов, О.И. Синицина, Т.Г. Толстикова, И.А. Григорьев, С.В. Морозов, Ю.В. Юшкова
    Новые ионные конъюгаты на основе a-токоферилсукцината как потенциальные цитотоксические агенты1
    Биоорганическая химия. 2018. Т. 44. № 3. С. 325-332. doi:10.7868/S0132342318030089, IF=0.838
  12. Antiulcerogenic activity of borneol derivatives/ M. S. Borisova, O. I. Yarovaya, M. D. Semenova, T. G. Tolstikova, N. F. Salakhutdinov// Russian Chemical Bulletin, 2018, V. 67, N 3, Pp 558-561 doi:10.1007/s11172-018-2110-y, IF=0.781
  13. A.O. Bryzgalov, T.G. Tolstikova, E.E. Shults, K.O. Petrova
    Natural Products as a Source of Antiarrhythmic Drugs
    Mini-Reviews in Medicinal Chemistry, 2018, V. 18, N 4, Pp 345 - 362 doi:10.2174/1389557516666161104144815, IF=2.645
  14. Q. Zhang, N.E. Polyakov, Yu.S. Chistyachenko, M.V. Khvostov, T.S. Frolova, T.G. Tolstikova, A.V. Dushkin, W. Su
    Preparation of curcumin self-micelle solid dispersion with enhanced bioavailability and cytotoxic activity by mechanochemistry
    Drug Delivery, 2018, V. 25, N 1, P. 198-209 doi:10.1080/10717544.2017.1422298, IF=3.095
  15. Avgustinovich D.F., Katokhin A.V., Kontsevaya G.V., Lvova M.N., Vishnivetskaya G.B., Kashina E.V., Marenina M.K., Maksimova G.A., Zav'yalov E.L., Mordvinov V.A.
    A comparative study of opistrorchis felineus (RIVOLTA, 1884) infection in inbred C57BL/6 AND outbred CD-1 mice
    Паразитология. 2018. Т. 52. № 1. С. 19-31

2017
  1. R. Kong, X. Zhu, E.S. Meteleva, Yu.S. Chistyachenko, L.P. Suntsova, N.E. Polyakov, M.V. Khvostov, D.S. Baev, T.G. Tolstikova, J. Yu, A.V. Dushkin, W. Su
    Enhanced solubility and bioavailability of simvastatin by mechanochemically obtained complexes
    International Journal of Pharmaceutics, 2017, V. 534, N 1-2, Pp 108-118 doi:10.1016/j.ijpharm.2017.10.011, IF=3.648
  2. K.Yu. Ponomarev, E.A. Morozova, E.V. Suslov, D.V. Korchagina, T.G. Tolstikova, K.P. Volcho, N.F. Salakhutdinov
    Synthesis and Analgesic Activity of 5,7- and 6-Substituted Diazaadamantanes Containing Monoterpene Moieties
    Chemistry of Natural Compounds, 2017, V. 53, N 6, Pp 1131-1136 doi:10.1007/s10600-017-2216-8, IF=0.46
  3. O.S. Patrusheva, A.V. Pavlova, D.V. Korchagina, T.G. Tolstikova, K.P. Volcho, N.F. Salakhutdinov
    Synthesis and Analgesic Activity of 4,7-Dimethyl-3,4,4a,5,8,8a-Hexahydro-2-Chromen-4,8-Diols Containing Alkyl-Substituted Aromatic Moieties
    Chemistry of Natural Compounds, 2017, V. 53, N 6, Pp 1066-1071 doi:10.1007/s10600-017-2202-1, IF=0.46
  4. I.M. Yermak, N.P. Mischchenko, V.N. Davydova, V.P. Glazunov, D.V. Tarbeeva, A.O. Kravchenko, E.A. Pimenova, I.V. Sorokina
    Carrageenans-Sulfated Polysaccharides from Red Seaweeds as Matrices for the Inclusion of Echinochrome
    Marine drugs, 2017, V. 15 , N 11 , Art Number 337 doi:10.3390/md15110337, IF=3.503
  5. I.I. Popadyuk, A.V. Markov, E.A. Morozova, V.O. Babich, O.V. Salomatina, E.B. Logashenko, M.A. Zenkova, T.G. Tolstikova, N.F. Salakhutdinov
    Synthesis and evaluation of antitumor, anti-inflammatory and analgesic activity of novel deoxycholic acid derivatives bearing aryl- or hetarylsulfanyl moieties at the C-3 position
    Steroids, 2017, V. 127, Pp 1-12 doi:10.1016/j.steroids.2017.08.016, IF=2.282
  6. A.V. Lipeeva, D.S. Baev, M.P. Dolgikh, T.G. Tolstikova, E.E. Shults
    Rapid Access to Oxazine Fused Furocoumarins and in vivo and in silico Studies of theirs Biological Activity
    Medicinal Chemistry, 2017, V.13, N 7, Pp 625-632 doi:10.2174/1573406413666170601114527, IF=2.331
  7. A. Predtetchinsk, E. Predtechenskaya, I. Sorokina, A. Guzev
    Gender features of hyperprolactinemia as a protective factor in animal models of multiple sclerosis
    Multiple sclerosis journal, 2017, V. 23, Pp 769-769, Приложение: 3 Аннотация к встрече: EP1463 (7th Joint European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS)-Americas-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ACTRIMS), Paris, FRANCE, Oct 25-28, 2017) doi:10.1177/1352458517731285, IF=4.84
  8. A.G. Galyamina, D.A. Smagin, I.L. Kovalenko, T.G. Tolstikova, N.N. Kudryavtseva
    Psychomotor disturbances and changes in the expression of neurotransmitter genes in the dorsal striatum of aggressive and defeated male mice
    European Neuropsychopharmacology, 2017, V. 27, pp S677-S677, S4 (30th Congress of the European-College-of-Neuropsychopharmacology (ECNP), Paris, France, Sep 02-05, 2017) doi:10.1016/S0924-977X(17)31260-9, IF=4.238
  9. D.O. Prima, D.S. Baev, E.V. Vorontsova, T.S. Frolova, I.Yu. Bagryanskaya, Yu.G. Slizhov, T.G. Tolstikova, A.Yu. Makarov, A.V. Zibarev
    New cancer cells apoptosis agents: Fluorinated aza-heterocycles
    AIP Conference Proceedings, V. 1882, N 1, 020057 (2017) (Proceedings of the International Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17), 23-26 May 2017, Tomsk, Russia) doi:10.1063/1.5001636
  10. Journal of Physics: Conference Series Volume 886, Issue 1, 29 August 2017, Номер статьи 012005/ // doi:10.1088/1742-6596/886/1/012005
  11. G.A. Maksimova, M.Y. Pakharukova, E.V. Kashina, N.A. Zhukova, A.V. Kovner, M.N. Lvova, A.V. Katokhin, T.G. Tolstikova, B. Sripac, V.A. Mordvinov
    Effect of Opisthorchis felineus infection and dimethylnitrosamine administration on the induction of cholangiocarcinoma in Syrian hamsters
    Parasitology International, 2017, V. 66, N 4, Pp 458-463 doi:10.1016/j.parint.2015.10.002, IF=1.743
  12. С.А. Борисов, М.В. Хвостов, Т.Г. Толстикова, А.В. Душкин, Ю.С. Чистяченко
    Фармакодинамические исследования комплекса включения Полисахарида лиственницы арабиногалактана с напроксеном
    Сибирский научный медицинский журнал, ТОМ 37, № 4, 2017,С 19-25
  13. K. Ponomarev, E. Morozova, A. Pavlova, E. Suslov, D. Korchagina, A. Nefedov, T. Tolstikova, K. Volcho, N. Salakhutdinov
    Synthesis and Analgesic Activity of Amines Combining Diazaadamantane and Monoterpene Fragments
    Medicinal Chemistry, 2017, V. 13 , N 8, Pp 773 - 779 doi:10.2174/1573406413666170525124316, IF=2.331
  14. I. Il'ina, A. Pavlova, D. Korchagina, O. Ardashov, T. Tolstikova, K. Volcho, N. Salakhutdinov
    Synthesis and analgesic activity of monoterpenoid-derived alkyl-substituted chiral hexahydro-2H-chromenes
    Medicinal Chemistry Research, 2017, V. 26, N 7, pp 1415-1426 doi:10.1007/s00044-017-1847-4, IF=1.276
  15. M.V. Khvostov, S.A. Borisov, T.G. Tolstikova, A.r V. Dushkin, B.D. Tsyrenova, Yu.S. Chistyachenko, N.E. Polyakov, G.G. Dultseva, A.A. Onischuk, S.V. An’kov
    Supramolecular Complex of Ibuprofen with Larch Polysaccharide Arabinogalactan: Studies on Bioavailability and Pharmacokinetics
    European Journal of Drug Metabolism and Pharmacokinetics, 2017, V. 42, N 3, pp 431-440 doi:10.1007/s13318-016-0357-y, IF=1.399
  16. Т.В. Попова, Н.О. Карабинцева, Л.Н. Рачковская, Т.Г. Толстикова, А.А. Котлярова, А.Ю. Летягин
    Возможности создания полифункционального серебросодержащего препарата с детоксикационным эффектом
    Фармация и фармакология. 2017. Т. 5. № 3. С. 242-253. doi:10.19163/2307-9266-2017-5-3-243-253
  17. Т.В. Попова, Н.О. Карабинцева, Т.Г. Толстикова
    Исследование ассортимента лекарственных средств, применяемых в терапии острых кишечных инфекций
    Журнал научных статей Здоровье и образование в XXI веке. 2017. Т. 19. № 10. С. 356-358.
  18. А.Б. Киселев, А.Ю. Овчинников, Т.Г. Толстикова, В.А. Чаукина, Н.А. Мирошниченко, Н.А. Жукова
    Транскутанная терапия назальной обструкции, сопровождающей интермиттирующий аллергический и острый инфекционный ринит
    Эффективная фармакотерапия. 2017. № 14. С. 8-12.
  19. В.И. Каледин, И.В. Сорокина, Н.А. Жукова, Т.Г. Толстикова, Л.А. Богданова, Т.С. Морозкова, Д.Е. Семенов
    Усиление общетоксического и ослабление гепатотоксического действия диэтилнитрозамина при торможении его метаболизма у мышей
    Российский физиологический журнал им. И.М. Сеченова. 2017. Т. 103. № 5. С. 527-532.
  20. Apoptosis as the basic mechanism of cytotoxic action of ursolic and pomolic acids in glioma cells/ T. S. Frolova, A. V. Lipeeva, D. S. Baev, Y. A. Tsepilov, O. I. Sinitsyna// Molecular Biology, 2017, V. 51, N 5, pp 705-711 doi:10.1134/S0026893317050090, IF=0.799
  21. A. Pavlova, O. Patrusheva, I. Il'ina, K. Volcho, T. Tolstikova, N. Salakhutdinov
    The Decisive Role of Mutual Arrangement of Hydroxy and Methoxy Groups in (3(4)-hydroxy-4(3)-methoxyphenyl)-4,7-dimethyl-3,4,4a,5,8,8ahexahydro- 2H-chromene-4,8-diols in their Biological Activity
    Letters in Drug Design & Discovery, 2017, V. 14, N 5, pp. 508-514 doi:10.2174/1570180813666161102142642, IF=1.169
  22. M. Yu. Khodanovich, I.V. Sorokina, V. Yu. Glazacheva, A.E. Akulov, N.M. Nemirovich-Danchenko, A.V. Romashchenko, T.G. Tolstikova, L.R. Mustafina, V.L. Yarnykh
    Histological validation of fast macromolecular proton fraction mapping as a quantitative myelin imaging method in the cuprizone demyelination model
    Scientific Reports, 2017, 7, Article number: 46686 doi:10.1038/srep46686, IF=4.258
  23. Киселев А.Б., Овчинников А.Ю., Толстикова Т.Г., Чаукина В.А., Мирошниченко Н.А., Жукова Н.А.
    Новый подход к ликвидации назальной обструкции при интермиттирующем аллергическом и остром инфекционном ринитах
    Российская оториноларингология. 2017. № 2 (87). С. 131-136
  24. A.S. Sokolova, O.I. Yarovaya, A.A. Shtro, M.S. Borisova, E.A. Morozova, T.G. Tolstikova, V.V. Zarubaev, N.F. Salakhutdinov
    Synthesis and biological activity of heterocyclic borneol derivatives
    Chemistry of Heterocyclic Compounds, 2017, V. 53, N 3, pp 371-377 doi:10.1007/s10593-017-2063-3, IF=0.893
  25. T.A. Vaganova, A.I. Plekhanov, A.E. Simanchuk, S.L. Mikerin, E.V. Spesivtsev, E.V. Karpova, T.S. Frolova, E.V. Malykhin
    Synthesis and characterization of novel polyhalogenaromatic polyimide material for electro-optic applications
    Journal of Fluorine Chemistry, 2017, V. 195, Pp 70-78 doi:10.1016/j.jfluchem.2017.01.010, IF=2.101
  26. A.S. Sokolova, О.I. Yarovaya, D.S. Baev, А.V. Shernyukov, A.A. Shtro, V.V. Zarubaev, N.F. Salakhutdinov
    Aliphatic and alicyclic camphor imines as effective inhibitors of influenza virus H1N1
    European Journal of Medicinal Chemistry, 2017, V. 127, Pp 661-670 doi:10.1016/j.ejmech.2016.10.035, IF=4.519
  27. Л.Г. Бурова, И.В. Широких, С.С. Патрушев, Т.Г. Толстикова, Э.Э. Шульц
    Взаимосвязь структура-антибактериальная активность в ряду производных изоалантолактона
    Фундаментальная и клиническая медицина. 2017. Т. 2. № 1. С. 28-34.

2016
  1. T.S. Khlebnicova, Y.A. Piven, F.A. Lakhvich, I.V. Sorokina, T.G. Tolstikova
    Fluorine-containing lupane triterpenoid acid derivatives: synthesis and biological evaluation as potential anti-inflammatory agents
    Известия Национальной академии наук Беларуси. Серия химических наук. Минск. “Беларуская навука.” 2016. C. 81-82.
  2. S.I. Zhivetyeva, O.D. Zakharova, L.P. Ovchinnikova, D.S. Baev, I.Yu. Bagryanskaya, V.D. Shteingarts, T.G. Tolstikova, G.A. Nevinsky, E.V. Tretyakov
    Phosphonium betaines derived from hexafluoro-1,4-naphthoquinone: Synthesis and cytotoxic and antioxidant activities
    Journal of Fluorine Chemistry, V. 192, Part A, December 2016, Pp 68-77 doi:10.1016/j.jfluchem.2016.10.014, IF=2.213
  3. A.D. Rogachev, O.I. Yarovaya, S.V. Ankov, M.V. Khvostov, T.G. Tolstikova, A.G. Pokrovsky, N.F. Salakhutdinov
    Development and validation of ultrafast LC–MS/MS method for quantification of anti-influenza agent camphecene in whole rat blood using dried blood spots and its application to pharmacokinetic studies
    Journal of Chromatography B, Volumes 1036-1037, 15 November 2016, Pages 136-141 doi:10.1016/j.jchromb.2016.10.009, IF=2.687
  4. M.A. Gilinsky, T.P. Johnston, N.A. Zhukova, N.I. Dubrovina, T.V. Latysheva, S.E. Naumenko, R.A. Sukhovershina
    Methylated arginine analogues: their potential role in atherosclerosis and cognition using the poloxamer-407-induced mouse model of dyslipidemia
    Canadian Journal of Physiology and Pharmacology, 2016, V. 94, N 11, Pp 1122-1131 doi:10.1139/cjpp-2016-0104, IF=1.703
  5. DOI: 10.2174/1573406412666160129105115/ http://benthamscience.com/journals/medicinal-chemistry/article/138908/// doi:10.2174/1573406412666160129105115 , IF=1.457
  6. O.D. Zakharova, T.S. Frolova, Yu.V. Yushkova, E.I. Chernyak, A.G. Pokrovsky, M.A. Pokrovsky, S.V. Morozov, O.I. Sinitsina, I.A. Grigor'ev, G.A. Nevinsky
    Antioxidant and antitumor activity of trolox, trolox succinate, an α-tocopheryl succinate conjugates with nitroxides
    European Journal of Medicinal Chemistry, 2016, V. 122, Pages 127-137 doi:10.1016/j.ejmech.2016.05.051, IF=3.901
  7. I.V. Sorokina, T.G. Tolstikova, A.V. Volod'ko, I.M. Yermak
    Modification of Biological Properties of k-Carrageenan in Polyionic Complexes with Chitosan
    Achievements in the Life Sciences,2016, V. 10, Supplement, Page S51 (http://www.sciencedirect.com/science/article/pii/S2078152016301900) doi:10.1016/j.als.2016.12.050
  8. A.A. Onischuk, T.G. Tolstikova, S.V. An'kov, A.M. Baklanov, S.V. Valiulin, M.V. Khvostov, I.V. Sorokina, G.G. Dultseva, N.A. Zhukovа
    Ibuprofen, Indomethacin and Diclofenac Sodium Nanoaerosol: Generation, Inhalation Delivery and Biological Effects in Mice and Rats
    Journal of Aerosol Science, V. 100, October 2016, Pp 164-177 doi:10.1016/j.jaerosci.2016.05.005, IF=2.278
  9. Dihydropyrimidin-2(1H)-one and its analogues as a platform for the design and synthesis of new biologically active compounds/ P Shkurko, T G Tolstikova, V F Sedova// RUSS CHEM REV, 2016, , 2016, 85 (10), 1056-1096 doi:10.1070/RCR4586, IF=3.687
  10. Т.С. Фролова, Д.С. Баев, О.И. Синицына
    ИССЛЕДОВАНИЕ ЦИТОТОКСИЧЕСКИХ СВОЙСТВ ТРИТЕРПЕНОВЫХ КИСЛОТ ПРОТИВ КЛЕТОК ГЛИОМЫ
    Успехи современной науки и образования. 2016. Т. 4. № 9. С. 14-18.
  11. A.V. Pavlova, E.V. Nazimova, O.S. Mikhal'chenko, I.V. Il'ina, D.V. Korchagina, O.V. Ardashov, E.A. Morozova, T.G. Tolstikova, K.P. Volcho, N.F. Salakhutdinov
    Synthesis and Analgesic Activity of 4,7-Dimethyl-3,4,4a,5,8,8a-Hexahydro-2H-Chromen-4,8-Diols Containing Thiophene Substituents
    Chemistry of Natural Compounds, , 2016, V. 52, N 5, pp 813-820 doi:10.1007/s10600-016-1785-2, IF=0.472
  12. A. Sokolova, A. Pavlova, N. Komarova, O. Ardashov, A. Shernyukov, Yu. Gatilov, O. Yarovaya, T. Tolstikova, N. Salakhutdinov
    Synthesis and analgesic activity of new α-truxillic acid derivatives with monoterpenoid fragments
    Medicinal Chemistry Research, 2016, V. 25, N 8, pp 1608-1615 doi:10.1007/s00044-016-1593-z, IF=1.435
  13. Cardiotoxic and Dyslipidemic Effects of Doxorubicin and Betulinic Acid Amide/ M. G. Klinnikova, E. L. Lushnikova, E. V. Koldysheva, T. G. Tolstikova, I. V. Sorokina, E. I. Yuzhik, M. M. Mzhelskaya// Bulletin of Experimental Biology and Medicine,, 2016, V. 162, N 2, pp 277-282 doi:10.1007/s10517-016-3594-9, IF=0.448
  14. T.G. Tolstikova, M.V. Khvostov, N.A. Zhukova, N.V. Shikina, Ismagilov
    Synthesis and safety evaluation of gold nanoparticles in the in vivo experiment
    Химия в интересах устойчивого развития. 2016. Т. 24. № 4. С. 555-560. doi:10.15372/KhUR20160416
  15. E. Nazimova, A. Pavlova, O. Mikhalchenko, I. Il'ina, D. Korchagina, T. Tolstikova, K. Volcho, N. Salakhutdinov
    Discovery of highly potent analgesic activity of isopulegol-derived (2R,4aR,7R,8aR)-4,7-dimethyl-2-(thiophen-2-yl)octahydro-2H-chromen-4-ol
    Medicinal Chemistry Research, 2016, V. 25, N 7, pp 1369-1383 doi:10.1007/s00044-016-1573-3, IF=1.435
  16. Genotoxicity assessment of low-level doses of gamma radiation with the SOS chromotest and the Ames test/ A. Ya. Bolsunovsky, O. I. Sinitsyna, T. S. Frolova, E. A. Vasyunina, D. V. Dementyev// Doklady Biochemistry and Biophysics, July 2016, V. 469, N 1, pp 309-312 doi:10.1134/S1607672916040190, IF=0.393
  17. L.N. Rachkovskaya, T.V. Popova, A. Yu Letyagin, T.G. Tolstikova, M.A. Korolyov, N. Bogdanchikova, A.N. Pestryakov, A.A. Kotlyarova, V. Burmistrov, V.I. Konenkov
    Silver containing sorbents: Physicochemical and biological properties
    Resource-Efficient Technologies, 2016, V. 2, N 2, Pages 43-49 doi:10.1016/j.reffit.2016.06.001
  18. DOI: 10.2174/1567201812666150605104944/ http://benthamscience.com/journals/current-drug-delivery/article/132016/// doi:10.2174/1567201812666150605104944, IF=1.445
  19. Amide of Lambertian Acid Suppresses Hyperactivation of Inotropic Glutamate Receptors, but not Synaptic Potentiation in Hippocampal Sections/ S. O. Vechkapova, T. A. Zapara, E. A. Morozova, A. L. Proskura, E. E. Schul'ts, T. G. Tolstikova, A. S. Ratushnyak// Bulletin of Experimental Biology and Medicine doi:10.1007/s10517-016-3509-9, IF=0.448
  20. The effect of a lithium-containing composition on ethanol-induced changes in liver and brain within the experiments on mice/ Kotlyarova, A.Yu. Letyagin, T.G. Tolstikova, N.P. Bgatova, L.N. Rachkovskaya// The Siberian Scientific Medical Journal, 2015, V.. 35, № 2, 2015, Pp 29-34
  21. Research of the allergenic properties of new silver containing finely particulate sorbent/ T.V. Popova, T.G. Tolstikova, A.Yu. Letyagin, L.N. Rachkovskaya// The Siberian Scientific Medical Journal, 2015, V.. 35, № 2, 2015, Pp 24-28
  22. И.П. Жураковский, Т.Г. Толстикова, И.В. Сорокина, Н.А. Жукова, М.П. Борисова, И.О. Маринкин, А.И. Аутеншлюс
    Эффективность применения β-аланинамида бетулоновой кислоты при стафиллококковом остеомиелите у крыс Вистар
    Современные проблемы науки и образования. -2016. - № 5. (Электронный журнал) URL: https://www.science-education.ru/ru/article/view?id=25172.
  23. Specific Features of Progression of the Parasitic Invasion, caused by Opisthorchis felineus, in Golden Hamsters/ D. E. Semenov, N. A. Zhukova, T. G. Tolstikova, I. V. Sorokina, E. L. Lushnikova// Bulletin of Experimental Biology and Medicine, 2016, V. 161, N 4, Pp 481-486 doi:10.1007/s10517-016-3443-x, IF=0.448
  24. D.F. Avgustinovich, M.K. Marenina, S.Ya. Zhanaeva, M.V. Tenditnik, A.V. Katokhin, K.S. Pavlov, A.Yu. Sivkov, G.B. Vishnivetskaya, M.N. Lvova, T.G. Tolstikova, V.A. Mordvinov
    Combined effects of social stress and liver fluke infection in a mouse model
    Brain, Behavior, and Immunity, 2016, V. 53, Pp 262-272 doi:10.1016/j.bbi.2016.01.012, IF=5.874
  25. Experimental Study of the Biocompatibility of Soft Tissues and a Finely Dispersed Sorbent Containing Silver/ T. V. Popova, T. G. Tolstikova, A. Yu. Letyagin, L. N. Rachkovskaya, V. A. Burmistrov// Pharmaceutical Chemistry Journal, 2016, V. 50, N 3, pp 152-155, IF=0.46
  26. И.В. Сорокина, Н.А. Жукова, Т.Г. Толстикова, С.А. Попов, Э.Э. Шульц
    Бетамид - средство с противоопухолевой активностью, снижающее гепато- и нефротоксические эффекты цитостатической полихимиотерапии
    Российский биотерапевтический журнал. 2016. Т. 15. № 1. С. 103-104.
  27. M.K. Fomina, D.F. Avgustinovich, T.G. Tolstikova
    Studies of the Effects of a Complex of Buspirone with Glycyrrhyzic Acid on the Behavior of Mice during Formation of an Anxious-Depressive State
    Neuroscience and Behavioral Physiology, 2016, V. 46, N 2, pp 153-159 doi:10.1007/s11055-015-0212-7
  28. Synthesis, properties, and application of 4-nitrosemicarbazones/ V. S. Glukhacheva,S. G. Il'yasov, G. V. Sakovich, T. G. Tolstikova, A. O. Bryzgalov, N. V. Pleshkova// Russian Chemical Bulletin, February 2016, V. 65, N 2, pp 550-560 doi:10.1007/s11172-016-1336-9, IF=0.578
  29. T.A. Korolenko, T.P. Johnston, F.V. Tuzikov, N.A. Tuzikova, A.B. Pupyshev, V.K. Spiridonov, N.V. Goncharova, I.V. Maiborodin, N.A. Zhukova
    Early-stage atherosclerosis in poloxamer 407-induced hyperlipidemic mice: pathological features and changes in the lipid composition of serum lipoprotein fractions and subfractions
    Lipids in Health and Disease, 15:16, 22 January 2016 doi:10.1186/s12944-016-0186-7, IF=2.137
  30. Т.В. Попова, Т.Г. Толстикова, Л.Н. Рачковская
    Исследование нового пористого носителя в серебросодержащей композиции на модели фарминдуцированных язв желудка и двенадцатиперстной кишки
    Интер-медикал 2016, Т..17, N 1 , с.56-59
  31. V.A. D'yakonov, L.U. Dzhemileva, A.A. Makarov, A.R. Mulyukova, D.S. Baev, E.K. Khusnutdinova, T.G. Tolstikova, U.M. Dzhemilev
    nZ,(n + 4)Z-Dienoic fatty acids: a new method for the synthesis and inhibitory action on topoisomerase I and IIα
    Medicinal Chemistry Research, 2016, V. 25, N 1, pp 30-39 doi:10.1007/s00044-015-1446-1, IF=1.435
  32. EFFECT OF NOVEL OINTMENT COMPOSITION AG/TAGA: CHITOSAN-GEL ON HEALING OF EXPERIMENTAL WOUNDS WITH DIFFERENT ORIGINS/ Popova T.V., Tolstikova T.G., Letyagin A.Yu., Zhukova N.A., Bgatova N.P., Rachkovskaya L.N., Kotlyrova A.A., Burmistrov V.A.// Byulleten Sibirskoy Meditsiny, 2016, Т. 15, № 1, С. 47-54 doi:10.20538/1682-0363-2016-1-47-54
  33. Effects of the lithium - containing sorbent on terms of behavioral reactions under chronic alcohol intoxication model/ A.A. Kotlyarova, A.Yu. Letyagin, T.G. Tolstikova, T.V. Popova, L.N. Rachkovskaya EFFECT OF NOVEL OINTMENT COMPOSITION AG/TAGA: CHITOSAN-GEL ON HEALING OF EXPERIMENTAL WOUNDS WITH DIFFERENT ORIGINS Popova T.V.1, Tolstikova T.G.2, Letyagin A.Yu.1, Zhukova N.A.2, Bgatova N.P.1, Rachkovskaya L.N.1, Kotlyrova A.A.1, Burmistrov V.A.1// Бюллетень сибирской медицины, 2016, Т. 15, № 1, С. 30-36. doi:10.20538/1682-0363-2016-1-30-36

2015
  1. Yu.S. Chistyachenko, E.S. Meteleva, M.Y. Pakharukova, A.V. Katokhin, M.V. Khvostov, A.I. Varlamova, I.I. Glamazdin, S.S. Khalikov, N.E. Polyakov, I.A. Arkhipov, T.G. Tolstikova, V.A. Mordvinov, A.V. Dushkin, N.Z. Lyakhov
    A Physicochemical and Pharmacological Study of the Newly Synthesized Complex of Albendazole and the Polysaccharide Arabinogalactan from Larch Wood
    Current Drug Delivery, 2015, V. 12, N 5, Pp 477-490 doi:10.2174/1567201812666150518094739, IF=1.478
  2. K. Ponomarev, A. Pavlova, E. Suslov, O. Ardashov, D. Korchagina, A. Nefedov, T. Tolstikova, K. Volcho, N. Salakhutdinov
    Synthesis and analgesic activity of new compounds combining azaadamantane and monoterpene moieties
    Medicinal Chemistry Research, 2015, V. 24, N 12, pp 4146-4156 doi:10.1007/s00044-015-1464-z, IF=1.401
  3. A. Pavlova, O. Mikhalchenko, A. Rogachev, I. Il'ina, D. Korchagina, Yu. Gatilov, T. Tolstikova, K. Volcho, N. Salakhutdinov
    Synthesis and analgesic activity of stereoisomers of 2-(3(4)-hydroxy-4(3)-methoxyphenyl)-4,7-dimethyl-3,4,4a,5,8,8a-hexahydro-2H-chromene-4,8-diols
    Medicinal Chemistry Research, 2015, V 24, N 11, pp 3821-3830 doi:10.1007/s00044-015-1426-5, IF=1.401
  4. Siberian Opisthorchosis. Biology, Distribution and Development of New Preparations for Its Treatment/ MORDVINOV V.A., PAKHARUKOVA M. YU., KATOKHIN A.V., DUSHKIN A.V., CHISTYACHENKO YU. S., BELOUSOV A.I., KHVOSTOV M.V., ZHUKOVA N.A., KHALIKOV S.S., TOLSTIKOVA T.G., LYAKHOV N.Z.// doi:10.15372/KhUR20150511
  5. Investigation of degenerative processes in the femoral head of rats with prolonged alcohol intoxication/ A.G. Shusharin, M.S. Biruykova, M.P. Polovinka, N.A. Zhukova, T.G. Tolstikova// The Siberian Scientific Medical Journal, 2015, V. 35, № 4, Pp 4-8
  6. Investigation of degenerative processes in the femoral head of rats with prolonged alcohol intoxication/ A.G. Shusharin, M.S. Biruykova, M.P. Polovinka, N.A. Zhukova, T.G. Tolstikova// The Siberian Scientific Medical Journal, 2015, V. 35, № 4, Pp 4-8
  7. The morphofunctional and biochemical characteristics of opisthorchiasis-associated cholangiocarcinoma in a Syrian hamster model/ G. A. Maksimova , M. Y. Pakharukova, E. V. Kashina, N. A. Zhukova, M. N. Lvova, M. V. Khvostov, D. S. Baev, A. V. Katokhin, T. G. Tolstikova, V. A. Mordvinov// Russian Journal of Genetics: Applied Research, June 2016, V. 6, N 4, pp 454-462, doi:10.1134/S2079059716040134 doi:10.1134/S2079059716040134
  8. Д.Е. Семенов, Н.А. Жукова, Т.Г. Толстикова, И.В. Сорокина, М.С. Бирюкова, Е.П. Иванова
    Патоморфогенез токсических поражений печени, индуцированных полихимиотерапией и тетрахлорметаном и их коррекция тритерпеновыми производными
    В книге: ФУНДАМЕНТАЛЬНЫЕ АСПЕКТЫ КОМПЕНСАТОРНО-ПРИСПОСОБИТЕЛЬНЫХ ПРОЦЕССОВ МОЛЕКУЛЯРНО-КЛЕТОЧНЫЕ И МЕДИКО-ЭКОЛОГИЧЕСКИЕ ПРОБЛЕМЫ КОМПЕНСАЦИИ И ПРИСПОСОБЛЕНИЯ. Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт экспериментальной и клинической медицины». Ответственный редактор: академик РАН, доктор медицинских наук, профессор В.А. Шкурупий. Новосибирск, 2015. С. 259-260.
  9. Е.А. Морозова, Т.Г. Толстикова, А.А. Старостенко, Т.Н. Быстрова
    Исследование хронической токсичности декстразида
    В книге: ФУНДАМЕНТАЛЬНЫЕ АСПЕКТЫ КОМПЕНСАТОРНО-ПРИСПОСОБИТЕЛЬНЫХ ПРОЦЕССОВ МОЛЕКУЛЯРНО-КЛЕТОЧНЫЕ И МЕДИКО-ЭКОЛОГИЧЕСКИЕ ПРОБЛЕМЫ КОМПЕНСАЦИИ И ПРИСПОСОБЛЕНИЯ. Федеральное государственное бюджетное научное учреждение «Научно-исследовательский институт экспериментальной и клинической медицины». Ответственный редактор: академик РАН, доктор медицинских наук, профессор В.А. Шкурупий. Новосибирск, 2015. С. 176-177.
  10. I.V. Nechepurenko, U.A. Boyarskikh, M.V. Khvostov, D.S. Baev, N.I. Komarova, M.L. Filipenko, T.G. Tolstikova, N.F. Salakhutdinov
    Hypolipidemic Berberine Derivatives with a Reduced Aromatic Ring C
    Chemistry of Natural Compounds, 2015, V 51, N 5, pp 916-922 doi:10.1007/s10600-015-1447-9, IF=0.509
  11. Analgesic Effect of Several Nonsteroidal Anti-Inflammatory Drug Nanoaerosols/ S. V. An'kov, T. G. Tolstikova , A. A. Onishchuk, M. V. Khvostov, I. V. Sorokina, A. M. Baklanov, V. M. Fomin, V. V. Boldyrev// Pharmaceutical Chemistry Journal, 2016, V. 49, N 10, pp 680-682 doi:10.1007/s11094-016-1352-y, IF=0.451
  12. V.A. D'yakonov, L.U. Dzhemileva, A.A. Makarov, A.R. Mulyukova, D.S. Baev, E.K. Khusnutdinova, T.G. Tolstikova, U.M. Dzhemilev
    11-Phenylundeca-5Z,9Z-dienoic Acid: Stereoselective Synthesis and Dual Topoisomerase I/IIα Inhibition
    CURRENT CANCER DRUG TARGETS, 2015, V. 15, N 6, Pp 504-510 doi:10.2174/1568009615666150506093155, IF=3.522
  13. A.V. Lipeeva, M.A. Pokrovsky, D.S. Baev, M.M. Shakirov, I.Y. Bagryanskaya, T.G. Tolstikova, A.G. Pokrovsky, E.E. Shults
    Synthesis of 1H-1,2,3-triazole linked aryl(arylamidomethyl) - dihydrofurocoumarin hybrids and analysis of their cytotoxicity
    European Journal of Medicinal Chemistry, V.100, 2015, Pp 119-128 doi:10.1016/j.ejmech.2015.05.016, IF=3.447
  14. Magnetoelectric system for stimulation of hematopoiesis at decrease in quantity of blood cells and age changes of volume of red marrow Magnetoelectric system for stimulation of hematopoiesis at decrease in quantity of blood cells and age changes of volume of red marrow/ Belik D.V., Emtsev A.S., Schumeyko A.V., Khvostov M.V.//
  15. O. B. Shevelev, A.E. Akulov, A. S. Dotsenko, G. V. Kontsevaya, M. A. Zolotykh, L.A. Gerlinskaya, S. G. Veprev, T. N. Goryachkovskaya., N. A. Zhukova, N. A. Kolchanov, S. E. Pel'tek,M. P. Moshkin
    Neurometabolic Effect of Altaian Fungus Ganoderma lucidum (Reishi Mushroom) in Rats Under Moderate Alcohol Consumption
    Alcoholism: Clinical and Experimental Research, 2015, V. 39, N 7, pp 1128-1136. doi:10.1111/acer.12758, IF=3.205
  16. М.С. Бирюкова, Н.А. Жукова, И.В. Сорокина, Т.Г. Толстикова
    Противоопухолевая и гепатопротекторная активность морфолиниламида дигидробетулоновой кислоты
    В сборнике: НОВЫЕ ИНФОРМАЦИОННЫЕ ТЕХНОЛОГИИ В МЕДИЦИНЕ, БИОЛОГИИ, ФАРМАКОЛОГИИ И ЭКОЛОГИИ материалы Международной конференции: Весенняя сессия. Под редакцией Е.Л. Глориозова. 2015. С. 302-311.
  17. Н.А. Жукова, Т.Г. Толстикова, И.В. Сорокина, М.П. Бирюкова, Д.Е. Семенов
    Патоморфология поражений печени различного генеза и их коррекция бетулоновой кислотой и ее амидом
    В сборнике: НОВЫЕ ИНФОРМАЦИОННЫЕ ТЕХНОЛОГИИ В МЕДИЦИНЕ, БИОЛОГИИ, ФАРМАКОЛОГИИ И ЭКОЛОГИИ материалы Международной конференции: Весенняя сессия. Под редакцией Е.Л. Глориозова. 2015. С. 251-263.
  18. С.В. Аньков, Т.Г. Толстикова, А.А. Онищук, Н.А. Жукова, М.В. Хвостов
    Токсико-фармакологические свойства наноаэрозольной формы нестероидных противовоспалительных средств
    В сборнике: НОВЫЕ ИНФОРМАЦИОННЫЕ ТЕХНОЛОГИИ В МЕДИЦИНЕ, БИОЛОГИИ, ФАРМАКОЛОГИИ И ЭКОЛОГИИ материалы Международной конференции: Весенняя сессия. Под редакцией Е.Л. Глориозова. 2015. С. 239-244.
  19. Acetylenic derivatives of betulonic acid amide as a new type of compounds possessing spasmolytic activity/ A. I. Govdi, I. V. Sorokina, D. S. Baev, A. O. Bryzgalov, T. G. Tolstikova, G. A. Tolstikov, S. F. Vasilevsky// Russian Chemical Bulletin, 2015, V. 64, N 6, pp 1327-1334 doi:10.1007/s11172-015-1013-4, IF=0.481
  20. V. A. D'yakonov, L.U. Dzhemileva , A.A. Makarov, A. R. Mulukova, D. S. Baev, E. K. Khusnutdinova., T. G. Tolstikova , U. M. Dzhemilev
    Stereoselective synthesis of 11-phenylundeca-5Z,9Z-dienoic acid and investigation of its human topoisomerase I and II alpha inhibitory activity
    Bioorganic & Medicinal Chemistry Letters, V. 25, N 11, 2015, Pp 2405-2408 doi:10.1016/j.bmcl.2015.04.011, IF=2.42
  21. Yu.S. Chistyachenko, A.V. Dushkin, N.E. Polyakov, M.V. Khvostov, T.G. Tolstikova, G.A. Tolstikov, N.Z. Lyakhov
    Polysaccharide arabinogalactan from larch Larix sibirica as carrier for molecules of salicylic and acetylsalicylic acid: preparation, physicochemical and pharmacological study
    Drug Delivery, 2015, Vol. 22, No. 3 , Pages 400-407 doi:10.3109/10717544.2014.884655, IF=2.558
  22. Role of cAMP- and IKK-2-Dependent Signaling Pathways in Functional Stimulation of Mesenchymal Progenitor Cells with Alkaloid Songorine/ G. N. Zyuz’kov , V. V. Zhdanov, E. V. Udut, L. A. Miroshnichenko, A. V. Chaikovskii, E. V. Simanina, T. Yu. Polyakova, M. Yu. Minakova, V. V. Udut, T. G. Tolstikova, E. E. Shul’ts, L. A. Stavrova, Ya. V. Burmina, N. I. Suslov, A. M. Dygai// Bulletin of Experimental Biology and Medicine, September 2015, V. 159, N 5, pp 642-645 doi:10.1007/s10517-015-3036-0, IF=0.358
  23. Г.А. Толстиков, А.Г. Толстиков, Т.Г. Толстикова
    Берёза лечила и будет лечить
    В сборнике: Береза Сборник статей. РОССИЙСКАЯ АКАДЕМИЯ НАУК; Институт лингвистических исследований; Санкт-Петербургский научный центр. Санкт-Петербург, 2015. С. 83-126.
  24. Д.В. Белик, А.В. Шумейко, А.С. Емцев, М.В. Хвостов
    Биотехническая система для стимуляции гемопоэза при сниженном количестве клеток крови и возрастных изменениях объема красного костного мозга
    Научные исследования и разработки молодых ученых. 2015. № 4. С. 78-83.
  25. Curare-like camphor derivatives and their biological activity/ A. S. Sokolova, E. A. Morozova, V. G. Vasilev, O. I. Yarovaya, T. G. Tolstikova, N. F. Salakhutdinov// Russian Journal of Bioorganic Chemistry, March 2015, Volume 41, Issue 2, pp 178-185 doi:10.1134/S1068162015020156, IF=0.535
  26. Yu.P. Bogza, A.L. Katsiel’, A.N. Sharypova, T.G. Tolstikova, A.S. Fisyuk
    Synthesis and Biological Activity of 4H-Thieno[3,2-c]Chromene Derivatives
    Chemistry of Heterocyclic Compounds, March 2015, Volume 50, Issue 12, pp 1712-1718 doi:10.1007/s10593-015-1642-4, IF=0.621
  27. Г.А. Максимова, Н.А. Жукова, Е.В. Кашина, М.Н. Львова, А.В. Катохин, Т.Г. Толстикова, В.А. Мордвинов
    Роль opisthorchis felineus в индукции рака желчных протоков
    Паразитология. 2015. Т. 49. № 1. С. 3-11.
  28. A.I. Govdi, N.V. Sokolova, I.V. Sorokina, D.S. Baev, T.G. Tolstikova, V.I. Mamatyuk, D.S. Fadeev, S.F. Vasilevsky, V.G. Nenajdenko
    Synthesis of new betulinic acid–peptide conjugates and in vivo and in silico studies of the influence of peptide moieties on the triterpenoid core activity
    MedChemComm, 2015, V.6, N 1, pp. 230-238. doi:10.1039/c4md00236a, IF=2.495
  29. About the mechanism of membrane permeability enhancement by substances in their intermolecular complexes with polysaccharide arabinogalactan from larches Larix sibirica and Larix gmelinii/ A. V. Dushkin, Yu. S. Chistyachenko, D. A. Komarov, M. V. Khvostov, T. G. Tolstikova, I. F. Zhurko, I. A. Kirilyuk, I. A. Grigor’ev, N. Z. Lyakhov// Doklady Biochemistry and Biophysics, January 2015, Volume 460, Issue 1, pp 9-12 doi:10.1134/S1607672915010020, IF=0.343
  30. Involvement of PI3K, MAPK ERK1/2 and p38 in Functional Stimulation of Mesenchymal Progenitor Cells by Alkaloid Songorine/ G. N. Zyuz’kov, V. V. Zhdanov, L. A. Miroshnichenko, E. V. Udut, A. V. Chaikovskii, E. V. Simanina, M. G. Danilets, M. Yu. Minakova, V. V. Udut, T. G. Tolstikova, E. E. Shults, L. A. Stavrova, Ya. V. Burmina, A. M. Dygai// Bulletin of Experimental Biology and Medicine, 2015, V. 159, N 1, pp 58-61 doi:10.1007/s10517-015-2889-6, IF=0.358
  31. The synthesis and anti-inflammatory activity of propargylamino derivatives of naphthoquinonlevopimaric acid/ S. F. Vasilevsky, D. S. Baranov, A. I. Govdi, I. V. Sorokina, T. G. Tolstikova// Russian Journal of Bioorganic Chemistry, January 2015, Volume 41, Issue 1, pp 83-86 doi:10.1134/S1068162015010148, IF=0.535
  32. Synthesis of new combretastatin A-4 analogues and study of their anti-inflammatory activity/ M. P. Davydova, I. V. Sorokina, T. G. Tolstikova, V. I. Mamatyuk, D. S. Fadeev, S. F. Vasilevsky// Russian Journal of Bioorganic Chemistry, January 2015, Volume 41, Issue 1, pp 70-76 doi:10.1134/S1068162015010033, IF=0.535

2014
  1. A.A. Onischuk, T.G. Tolstikova, A.M. Baklanov, M.V. Khvostov, I.V. Sorokina, N.A. Zhukova, S.V. An’kov, O.V. Borovkova, G.G. Dultseva, V.V. Boldyrev, V.M. Fomin, G. Steven Huang
    Generation, inhalation delivery and anti-hypertensive effect of nisoldipine nanoaerosol
    J. Aerosol Science, 2014 , V. 78, P. 41-54. doi:10.1016/j.jaerosci.2014.08.004, IF=2.704
  2. Ю.С. Чистяченко, А.В. Душкин, М.В. Хвостов, Н.А. Жукова, Т.Г. Толстикова, А.И. Белоусов, М.Ю. Пахарукова, А.В. Катохин, В.А. Мордвинов, С.С. Халиков
    Перспективный противоописторхозный препарат на основе албендазола
    Теория и практика борьбы с паразитарными болезнями. 2014. № 15. С. 339-342., 2014, 15, 339-342
  3. I. Il’ina, O. Mikhalchenko, A. Pavlova, D. Korchagina, T. Tolstikova, K. Volcho, N. Salakhutdinov, E. Pokushalov
    Highly potent analgesic activity of monoterpene-derived (2S,4aR,8R,8aR)-2-aryl-4,7-dimethyl-3,4,4a,5,8,8a-hexahydro-2H-chromene-4,8-diols
    Medicinal Chemistry Research, 2014, V. 23, N 12, pp 5063-5073 doi:10.1007/s00044-014-1071-4, IF=1.402
  4. PT/Y Mice Are Sensitive to the Inhibitory Effect of o-Aminoazotoluene on Glucocorticoid Induction of Tyrosine Aminotransferase and Its Hepatocarcinogenic Effect/ T. S. Morozkova, L. A. Bogdanova, D. E. Semenov, N. A. Zhukova, N. A. Popova// Bulletin of Experimental Biology and Medicine, April 2015, V. 158, N 6, pp 789-793 doi:10.1007/s10517-015-2863-3, IF=0.365
  5. Betamid influence on remyelination in cuprizone-induced demyelination in mice/ A.N. Korablev, N.A. Popova, T.G. Tolstikova, A.A. Khodakov, E.V. Predtechenskaya// Вестник Уральской медицинской академической науки. 2014. № 3. С. 31-32.(In Russian)
  6. Role of NF-κB/IKK-Dependent Signaling in Functional Stimulation of Mesenchymal Progenitor Cells by Alkaloid Songorine/ G. N. Zyuz’kov, V. V. Zhdanov, E. V. Udut, L. A. Miroshnichenko, A. V. Chaikovskii, E. V. Simanina, M. G. Danilets, M. Yu. Minakova, V. P. Demkin, V. V. Udut, T. G. Tolstikova, E. E. Shults, V. I. Agafonov, A. M. Dygai// Bulletin of Experimental Biology and Medicine, March 2015, V. 158, N 5, pp 624-627 doi:10.1007/s10517-015-2822-z, IF=0.365
  7. В.С. Глухачева, С.Г. Ильясов, Т.Г. Толстикова
    Новые биологически активные вещества на основе арилнитропроизводных мочевин
    Южно-Сибирский научный вестник. 2014. № 4 (8). С. 15-17.
  8. Hepatoprotective Properties of Betulonic Acid Amide and Heptral in Toxic Liver Injury Induced by Carbon Tetrachloride in Combination with Ethanol/ D. E. Semenov, N. A. Zhukova, E. P. Ivanova, I. V. Sorokina, D. S. Baiev, G. I. Nepomnyashchikh, T. G. Tolstikova, M. S. Biryukova// Bulletin of Experimental Biology and Medicine, January 2015, V. 158, N 3, pp 336-341 doi:10.1007/s10517-015-2756-5, IF=0.365
  9. About the Mechanism of Analgesic Activity of Highly Efficient Analgesics of the New Structural Type: in vitro Experiments/ E.A. Morozova, T.A. Zapara, A.S.Ratushnyak, S.O.Vechkapova, T.G. Tolstikova, E.E. Shults// Chemistry for Sustainable Development, 2014. Т. 22. № 3. С. 289-293. (in russian)
  10. Effect of 2-Aminoadamantane Derivatives on Behavior of Mice in a Modified Light/Dark Test/ D. F. Avgustinovich, M. K. Fomina, E. V. Suslov, T. G. Tolstikova, K. P. Volcho, N. F. Salakhutdinov// Bulletin of Experimental Biology and Medicine, December 2014, V. 158, N 2, pp 213-218 doi:10.1007/s10517-014-2725-4, IF=0.365
  11. Effects of buspirone complex with glycyrrhizic acid on behavior of mice with anxious-depressive state/ М.К. Fomina, В.А. Avgustinovich, T.G. Tolstikova//
  12. Effect of the Nanoaerosol Form of Medical Products on Their Basic Activity/ S.V. Ankov, T.G. Tolstikova, M.V. Khvostov, A.A. Onischuk, A.M. Baklanov, V.V. Boldyrev// Chemistry for Sustainable Development. 2014. Т. 22. N 3. С. 223-227. (in russian)
  13. A.V. Pavlova, I.V. Il'ina, E.A. Morozova, D.V. Korchagina, S.Yu. Kurbakova, I.V. Sorokina, T.G. Tolstikova, K.P. Volcho, N.F. Salakhutdinov
    Potent Neuroprotective Activity of Monoterpene Derived 4-[(3aR,7aS)-1,3,3a,4,5,7a-Hexahydro-3,3,6-trimethylisobenzofuran-1-yl]-2-methoxyphenol in MPTP Mice Model
    Letters in Drug Design & Discovery, 2014, V. 11 N 5 pp. 611-617. doi:10.2174/1570180811666131210000316, IF=0.961
  14. S.F. Vasilevsky, D.S. Baranov, A.I. Govdi, I.V. Sorokina, T.G. Tolstikova, G.A. Tolstikov, I.V. Alabugin
    Click chemistry on diterpenes: anti-inflammatory activity of the acetylenic derivatives of levopimaric acid and products of their transformations
    ARKIVOС, 2014, V. 2014, Part (v), pp. 145 - 147. doi:10.3998/ark.5550190.p008.471, IF=1.75
  15. Complex Investigation of the Effects of Lambertianic Acid Amide in Female Mice under Conditions of Social Discomfort/ D. F. Avgustinovich, M. K. Fomina, I. V. Sorokina, T. G. Tolstikova// Bulletin of Experimental Biology and Medicine, 2014, V. 157, N 5, pp 583-587. doi:10.1007/s10517-014-2621-y, IF=0.365
  16. S. Kurbakova, I. Il'ina, A. Pavlova, D. Korchagina, O. Yarovaya, T. Tolstikova, K. Volcho, N. Salakhutdinov
    Synthesis and analgesic activity of monoterpenoid-derived 2-aryl-4,4,7-trimethyl-4a,5,8,8a-tetrahydro-4H-benzo[d][1,3]dioxin-8-ols
    Medicinal Chemistry Research, 2014, V. 23, N 4, pp 1709-1717. doi:10.1007/s00044-013-0772-4
  17. Ю.С. Чистяченко, М.В. Хвостов, А.И. Белоусов, Н.А. Жукова, М.Ю. Пахарукова, А.В. Катохин, С.С. Халиков, Т.Г. Толстикова, А.В. Душкин, В.А. Мордвинов, Н.З. Ляхов
    Физико-химические свойства и противоописторхозное действие механохимически синтезированных супрамолекулярных комплексов албендазола и полисахарида арабиногалактана из лиственниц Larix Sibirica и Larix gmelinii
    Доклады АН, Общая биология, 2014, Т.456, №6, p.741-744. doi:10.7868/S0869565214180273
  18. A.V. Volod'ko, V.N. Davydova, E. Chusovitin, I.V. Sorokina, M.P. Dolgikh, T.G. Tolstikova, S.A. Balagan, N.G. Galkin, I.M. Yermak
    Soluble chitosan–carrageenan polyelectrolyte complexes and their gastroprotective activity
    Carbohydrate Polymers, 2014, V. 101, Pp 1087-1093. doi:10.1016/j.carbpol.2013.10.049, IF=3.915

2013
  1. M. V. Khvostov, A. A. Chernonosov, T.G. Tolstikova, M. F. Kasakin, O. S. Fedorova, A. V. Dushkin
    Effect of Complexation with Arabinogalactan on Pharmacokinetics of “Guest” Drugs in Rats: For Example, Warfarin
    BioMed Research International, Volume 2013 (2013), Article ID 156381, 4 pages. doi:10.1155/2013/156381, IF=2.88
  2. В.С. Глухачева, С.Г. Ильясов, А.О. Брызгалов, Т.Г. Толстикова
    Синтез и антиаритмическая активность калиевой соли нитросемикарбазон камфанона
    Ползуновский вестник, 2013, N 3, С. 140-143.
  3. Hepatoprotective Activity of Betulonic Acid Amides Containing Piperidine or Pyrrolidine Nitroxide Moieties/ I. V. Sorokina, D. S. Baev, N. A. Zhukova, T. G. Tolstikova, A. N. Antimonova, N. I. Petrenko, E. E. Shults, and I. A. Grigor’ev// Russian Journal of Bioorganic Chemistry, 2013, V. 39, N 6, pp. 668–670. doi:10.1134/S1068162013060083, IF=0.523
  4. A.I. Govdi, S.F. Vasilevsky, N.V. Sokolova, I.V. Sorokina, T.G. Tolstikova, V.G. Nenajdenko
    Betulonic acid–peptide conjugates: synthesis and evaluation of anti-inflammatory activity
    Mendeleev Communications, 2013, V. 23, N 5, P.260-261. doi:10.1016/j.mencom.2013.09.007, IF=1.52
  5. O.V. Ardashov, A.V. Pavlova, D.V. Korchagina, K.P. Volcho, T.G. Tolstikova, N.F. Salakhutdinov
    3-Methyl-6-(prop-1-en-2-yl) cyclohex-3-ene-1,2-diol: the Importance of Functional Groups for Antiparkinsonian Activity
    Medicinal Chemistry, 2013, V. 9, N 5, P. 731-739. doi:10.2174/1573406411309050013, IF=1.373
  6. G. Maksimova, N.A. Zhukova, E.V. Kashina, M.N. Lvova, T.G. Tolstikova, A.V. Katokhin, V.A. Mordvinov
    Role of Opisthorchis felineus in the induction of bile duct cancer in experimental opisthorchiasis
    FEBS Journal, 2013, V. 280, Special Issue: SI Supplement: 1, P. 395-395. doi:10.1111/febs.12340, IF=4.25
  7. Pharmacological and physicochemical properties of mechanochemically synthesized supramolecular complexes of acetylsalicylic acid and polysaccharide arabinogalactan from lrches Larix sibirica and Larix gmelinii/ A. V. Dushkin, Yu. S. Chistyachenko, T. G. Tolstikova, M. V. Khvostov, N. E. Polyakov, N. Z. Lyakhov, G. A. Tolstikov// Doklady Biochemistry and Biophysics, 2013, V. 451, N 1, pp 180-182 doi:10.1134/S1607672913040030, IF=0.321
  8. A.O. Bryzgalov, V.E. Romanov, T.G. Tolstikova, E.E. Shults
    Lappaconitine: Influence of Halogen Substituent on the Antiarrhythmic Activity
    Cardiovascular & Hematological Agents in Medicinal Chemistry., 2013, V. 11 N 3, P. 211 - 217. doi:10.2174/18715257113119990083
  9. O. Mikhalchenko, I. Il’ina, A. Pavlova, E. Morozova, D. Korchagina, T. Tolstikova, E. Pokushalov, K. Volcho, N.Salakhutdinov
    Synthesis and analgesic activity of new heterocyclic compounds derived from monoterpenoids
    Medicinal Chemistry Research, 2013, V. 22, N 6, P. 3026-3034. doi:10.1007/s00044-012-0310-9, IF=1.611
  10. Synthesis of aminopropylamino derivatives of betulinic and oleanolic acids/ G. V. Giniyatullina, O. B. Kazakova, N. I. Medvedeva, I. V. Sorokina, N. A. Zhukova, T. G. Tolstikova, G. A. Tolstikov// Russian Journal of Bioorganic Chemistry, 2013, V. 39, N 3, pp 329-337 doi:10.1134/S1068162013020064, IF=0.523
  11. O.V. Ardashov, A.V. Pavlova, D.V. Korchagina, K.P. Volcho, T.G. Tolstikova, N.F. Salakhutdinov
    Antiparkinsonian activity of some 9-N-, O-, S- and C-derivatives of 3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol
    Bioorganic & Medicinal Chemistry, 2013, V. 21, N 5, P. 1082-1087. doi:10.1016/j.bmc.2013.01.003, IF=2.903
  12. Antitumor activity of amides of dihydrobetulonic acid in vitro and in vivo/ I. V. Sorokina, I. Ya. Mainagashev, N. A. Zhukova, D. V. Korchagina, T. G. Tolstikova, V. P. Nikolin, N. A. Popova, M. A. Pokrovskii, A. G. Pokrovskii, N. F. Salakhutdinov// Russian Journal of Bioorganic Chemistry, 2013, V. 39, N 2, pp 194-201 doi:10.1134/S106816201302012X, IF=0.523
  13. Cytotoxic and Immunomodulating Properties of Gold Nanoparticles/ M.V. Kharkova, A.V. Cherepanova, E.S. Morozkin, I.A. Zaporozhchenko, P.P. Laktionov, A.A. Strunov, E.V. Kiseleva, T.G. Tolstikova, N.V. Shikina, Z.R. Ismagilov, V.V. Vlasov// Chemistry for Sustainable Development, 2013, Т. 21,. № 2, pp. 179-188. (in russian).
  14. Cytotoxic and Immunomodulating Properties of Silver and Platinum Nanocomposites/ E.S. Morozkin, I.A. Zaporozhchenko, M.V. Kharkova, A.V. Cherepanova, P.P. Laktionov, V.V. Vlasov, B.G. Sukhov, G.F. Prozorova, B.A. Tofimov, M.V. Khvostov, T.G. Tolstikova// Chemistry for Sustainable Development, 2013, Т. 21,. № 2, pp. 155-163. (in russian).
  15. Efficient and safe medicines developed by Siberian scientists/ N. Z. Lyakhov, A. V. Dushkin, T. G. Tolstikova// Russian Chemical Bulletin, 2013, V. 62, N 1, pp: 235-241. doi:10.1007/s11172-013-0036-y, IF=0.423

2012
  1. Correction of Drug-Induced Hepatotoxicity with New Triterpene Derivatives in Transplanted RLS Lymphoma/ N. A. Zhukova, D. E. Semenov, E. P. Bessergeneva, I. V. Sorokina, T. G. Tolstikova// B EXP BIOL MED+, 2012, V. 154, N 3, pp 370-374. doi:10.1007/s10517-013-1953-3
  2. Gel chromatographic and toxicological studies of the mechanochemical transformations of water-soluble polysaccharides/ A. V. Dushkin, E. S. Meteleva, T. G. Tolstikova, A. V. Pavlova, M. V. Khvostov// PHARM CHEM J+, 2012, V. 46, N 10, pp. 630-633. doi:10.1007/s11094-013-0859-8, IF=0.372
  3. Joint effect of phenibut AND buspirone: experimental study/ D.F. Avgustinovich, T.G. Tolstikova// Вопросы биологической медицинской и фармацевтической химии. - 2012. - №12. - C. 59-63., IF=0.305
  4. M.V. Khvostov, T.G. Tolstikova, A.A. Chernonosov, O.S. Fedorova, G.I. Lifshits
    Pharmacokinetic Alterations of Warfarin in its clathrate With Arabinogalactan
    Asian J. Pharm. Clin. Res., 2012, V. 5, Suppl. 4, 251-252.
  5. Effect of Triterpene Derivatives on the Total Hepatocyte Count in the Liver of Rats with Toxic Hepatitis/ D. E. Semenov, N. A. Zhukova, E. P. Bessergeneva, I. V. Sorokina, D. S. Baev, B. M. Glukhov, G. I. Nepomnyaschikh, T. G. Tolstikova// B EXP BIOL MED+, 2012, V.153, N 6, pp 859-862. doi:10.1007/s10517-012-1844-z, IF=0.305
  6. Yu. Chen, Y.C. Hung, M.Y. Hong, A.A. Onischuk, J.C. Chiou, I.V. Sorokina, T. Tolstikova, G.S. Huang
    Control of In Vivo Transport and Toxicity of Nanoparticles by Tea Melanin
    Journal of Nanomaterials, 2012, V. 2012, Article ID 746960, 11 pages. doi:10.1155/2012/746960
  7. А.Э. Сазонов, В.А. Мордвинов, Г.А. Максимова, Н.А. Жукова, Е.В. Кашина, М.Н. Львова, А.В. Катохин, Т.Г. Толстикова, И.П. Каминский
    Экспериментальная модель описторхоза на хомяках (Mesocricetus auratus)
    Бюлл. Сибирской медицины, 2012, № 6, C.59-65
  8. T.G. Tolstikova, A.V. Pavlova, E.A. Morozova, T.M. Khomenko, K.P. Volcho, N.F. Salakhutdinov
    The analgesic activity of 8- ( trifluoromethyl)-1,2,3,4,5-benzopentathiepine-6-amine and its hydrochloride
    Lett. Drug Des. Discov., 2012, V. 9, N 5, 513-516. doi:10.2174/157018012800389296, IF=0.871
  9. E.A. Khatuntseva, V.M. Men’shov, A.S. Shashkov, Y.E. Tsvetkov, R.N. Stepanenko, R.Ya. Vlasenko, E.E. Shults, G.A. Tolstikov, T.G. Tolstikova, D.S. Baev, V.A. Kaledin, N.A. Popova, V.P. Nikolin, P.P. Laktionov, A.V. Cherepanova, T.V. Kulakovskaya, E.V. Kulakovskaya, N.E. Nifantiev
    Triterpenoid saponins from the roots of Acanthophyllum gypsophiloides Regel
    Beilstein J. Org. Chem., 2012, V. 8, 763-775. doi:10.3762/bjoc.8.87, IF=2.516
  10. Т.Г. Толстикова, Н.А. Жукова, Д.Е. Семёнов, Е.П. Бессергенева, И.В. Сорокина, Д.С. Баев, Б.М. Глухов
    Биохимические показатели крови и количество гепатоцитов в печени крыс с токсическим гепатитом при действии аланинамида бетулоновой кислоты
    Фундаментальные исследования, 2012, № 5, 120-123.
  11. Study of Skin Anti-Ageing and Anti-Inflammatory Effects of Dihydroquercetin, Natural Triterpenoids, and Their Synthetic Derivatives/ Ch.W. Lee, N.H. Park, J.W. Kim, B.H. Um, A.V. Shpatov, E.E. Shults, I.V. Sorokina, S.A. Popov// RUSS J BIOORG CHEM+, 2012, V. 38, N 3, pp. 328-334. doi:10.1134/S1068162012030028, IF=0.635
  12. О.С. Михальченко, К.П. Волчо, Т.Г. Толстикова, Н.Ф. Салахутдинов
    Синтез гетероциклических соединений взаимодействием альдегидов с монотерпеноидами в присутствии монтмориллонитовых глин
    Известия Уфимского научного центра РАН, 2012, № 4, 53-79.
  13. А.В. Душкин, Т.Г. Толстикова
    Новое "лицо" закомых лекарств
    Наука из первых рук, 2012, № 4 (46), 18-25.

2011
  1. К.Н. Сорокина, А.А. Тулупов, Т.Г. Толстикова, В.Ю. Усов
    Современные подходы к созданию контрастных препаратов для магнитно-резонансной томографической диагностики
    Бюллетень сибирской медицины, 2011, № 6, 79-85.
  2. Glycidipine, a Promising Hypotensive and Cardioprotective Agent/ T.G. Tolstikova, M.V. Khvostov, A.O. Bryzgalov, I.F. Belenichev, S.V. Pavlov// B EXP BIOL MED+, 2011, V.151, N 5, pp 597-600. doi:10.1007/s10517-011-1391-z, IF=0.305
  3. Е.П. Бессергенева, Н.А. Жукова, Т.Г. Толстикова, И.В. Сорокина
    Коррекция лекарственно – индуцированной гепатотоксичности новыми тритерпеновыми производными (экспериментальные исследования)
    Сибирский онкологический журнал, 2011 , № 6, 41-46.
  4. O.V. Ardashov, A.V. Pavlova, I.V. Il'ina, E.A. Morozova, D.V. Korchagina, E.V. Karpova, K.P. Volcho, T.G. Tolstikova, N.F. Salakhutdinov
    Highly potent activity of (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in animal models of Parkinson's disease
    J. Med. Chem., 2011, V. 54, N 11, 3866-74. doi:10.1021/jm2001579, IF=5.206
  5. T.G. Tolstikova, M.V. Khvostov, G.I. Lifshits, A.V. Dushkin, E.S. Meteleva
    Alteration of Warfarin’s Pharmacologic Properties in Clathrates with Glycyrrhizic Acid and Arabinogalactan
    Lett. Drug Des. Discov., 2011, V. 8, N 3, 201-204. doi:10.2174/157018011794578222, IF=0.667
  6. F.Vasilevsky. S, A.I. Govdi, I.V. Sorokina, T.G. Tolstikova, D.S. Baev, G.A. Tolstikov, V.I. Mamatuyk, I.V. Alabugin
    Rapid Access to New Bioconjugates of Betulonic Acid via Click Chemistry
    Bioorg. Med. Chem. Lett., 2011, V. 21, N 1, 62-65. doi:10.1016/j.bmcl.2010.11.072, IF=2.661
  7. Д.Ф. Августинович, М.К. Фомина, И.В. Сорокина, Т.Г. Толстикова
    Эффекты хронического введения комплекса буспирона с глицирризиновой кислотой на биохимические показатели крови тревожно-депрессивных мышей
    Вопр. Биол. Мед. Фарм. Хим., 2011, № 1, 28-30.



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